Use of tartaric acid for the production of sustainable Portland-free CSA-based mortars

The purpose of the study is to evaluate the effect of a tartaric acid-based set retarding admixture on rheological, elastic and physical performances of sustainable mortars manufactured with calcium sulfoaluminate, anhydrite and Supplementary Cementitious Materials replacing totally OPC. Experimental results indicated that the tartaric acid acts as superplasticizer and it is effective to extend the pot-life of mortars up to about 2 h. On the other hand, the set-retarding admixture provides a strong retardation of binder hydration resulting in a reduction of initial expansion and compressive strength at early ages. However, this retarding effect disappears at long ages

Pre-packed alkali activated cement-free mortars for repair of existing masonry buildings and concrete structures

This paper is aimed to study a ground granulated blast furnace slag activated with alkali powder to manufacture Portland-free mortars for conservation, restoration and retrofitting of existing masonry buildings and concrete structures. Activator/precursor represents the key parameter – not only for elasto-mechanical performances – influencing the rheological properties and the shrinkage: the higher the activator dosage, the higher the consistency class and shrinkage. Moreover, elastic modulus of slag-based mortars is lower than that of OPC-mortars at the same strength class. AAMs seem to be more promising for a sustainable future in construction since the GER and GWP are reduced by about 80% compared with traditional Portland cement mortars with the same compressive strength

Carba-D,L-allal- and -D,L-galactal-derived vinyl N-nosyl aziridines as useful tools for the synthesis of 4-deoxy-4-(N-nosylamino)-2,3-unsaturated-5a-carbasugars

The novel carba-D,L-allal- and carba-D,L-galactal-derived vinyl N-nosyl aziridines were prepared and the regio- and stereoselective behavior in opening reactions with O- and N-nucleophiles examined. The carbaglycosylating ability of the novel aziridines, as deduced by the amount of 1,4-addition products (1,4-regioselectivity) obtained in the acid-catalyzed methanolysis taken as a model reaction, is similar or superior to that observed with the corresponding carba-D,L-allal- and -D,L-galactal-derived vinyl epoxides, respectively. In all 1,2- and 1,4-addition products obtained, a –(N-nosylamino) group is regio- and stereoselectively introduced at the C(4) carbon of a 1,2- or 2,3-unsaturated carbasugar, susceptible to further elaborations toward aminocyclitol derivatives. The stereoselective synthesis of the corresponding, enantiomerically pure carba-D,L-allal- and -D,L-galactal-derived vinyl N-acetyl aziridines is also described

Città della Conciliazione, Grugliasco, Torino, Italy, 2005-2009

Pubblicazione del progetto Città Universitaria della Conciliazione a Grugliasco (TO) nel numero della rivista World Architecture dedicato ai progetti della Città di Torino

Closest-vector problem and the zero-temperature p-spin landscape for lossy compression

We consider a high-dimensional random constrained optimization problem in which a set of binary variables is subjected to a linear system of equations. The cost function is a simple linear cost, measuring the Hamming distance with respect to a reference configuration. Despite its apparent simplicity, this problem exhibits a rich phenomenology. We show that different situations arise depending on the random ensemble of linear systems. When each variable is involved in at most two linear constraints, we show that the problem can be partially solved analytically, in particular we show that upon convergence, the zero-temperature limit of the cavity equations returns the optimal solution. We then study the geometrical properties of more general random ensembles. In particular we observe a range in the density of constraints at which the system enters a glassy phase where the cost function has many minima. Interestingly, the algorithmic performances are only sensitive to another phase transition affecting the structure of configurations allowed by the linear constraints. We also extend our results to variables belonging to GF(q), the Galois field of order q. We show that increasing the value of q allows to achieve a better optimum, which is confirmed by the replica-symmetric cavity method predictions

Città Universitaria della Conciliazione a Grugliasco (TO)

Pubblicazione e testo critico del progetto della Città Universitaria della Conciliazione contenuto nell'articolo di Davide Tommaso Ferrando," A welcoming space. Sustainability as conciliation between work and family life" nel numero della rivista World Architecture dedicato ai progetti della Città di Torino

Città Universitaria della Conciliazione a Grugliasco

Pubblicazione e commento critico del progetto della Città Universitaria della Conciliazione contenuto nell'editoriale di Zhang Li (vice-direttore) "Soft sustainability: the Torino approach" del numero della rivista World Architecture dedicato alla Città di Torino

Microbial assisted phytodepuration for water reclamation: Environmental benefits and threats

Climate changes push for water reuse as a priority to counteract water scarcity and minimize water footprint especially in agriculture, one of the highest water consuming human activities. Phytodepuration is indicated as a promising technology for water reclamation, also in the light of its economic and ecological sustainability, and the use of specific bacterial inocula for microbial assisted phytodepuration has been proposed as a further advance for its implementation. Here we provided an overview on the selection and use of plant growth promoting bacteria in Constructed Wetland (CW) systems, showing their advantages in terms of plant growth support and pollutant degradation abilities. Moreover, CWs are also proposed for the removal of emerging organic pollutants like antibiotics from urban wastewaters. We focused on this issue, still debated in the literature, revealing the necessity to deepen the knowledge on the antibiotic resistance spread into the environment in relation to treated wastewater release and reuse. In addition, given the presence in the plant system of microhabitats (e.g. rhizosphere) that are hot spot for Horizontal Gene Transfer, we highlighted the importance of gene exchange to understand if these events can promote the diffusion of antibiotic resistance genes and antibiotic resistant bacteria, possibly entering in the food production chain when treated wastewater is used for irrigation. Ideally, this new knowledge will lead to improve the design of phytodepuration systems to maximize the quality and safety of the treated effluents in compliance with the 'One Health' concept

Tryptophan Metabolism as Source of New Prognostic Biomarkers for FAP Patients

Familial adenomatous polyposis (FAP), a common inherited form of colorectal cancer (CRC), causes the development of hundreds to thousands of colonic adenomas in the colorectum beginning in early adolescence. In absence of a prophylactic surgery, FAP patients almost inevitably develop CRC by the age of 40 to 50. The lack of valuable prognostic biomarkers for FAP patients makes it difficult to predict when the progression from adenoma to malignant carcinoma occurs. Decreased tryptophan (TRP) plasma levels and increased indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan hydroxylase 1 (TPH1) enzymatic activities have been associated to tumour progression in CRC. In the present study, we aimed at investigating whether an altered TRP metabolism might also exist in FAP patients. Our results highlighted that plasma levels of TRP and its main catabolites are comparable between FAP patients and healthy subject. On the contrary, FAP patients presented significantly higher TRP levels with respect to high-grade adenoma (ADE) subjects and CRC patients. Obtained data lead us to evaluate IDO1 and TPH1 enzymes activity in the study groups. For both enzymes, it was possible to discriminate correctly between FAP subject and ADE/CRC patients with high sensitivities and specificities. By receiver operating characteristic (ROC) curve analysis, the cut-off values of IDO1 and TPH1 enzymatic activities associated to the presence of an active malignant transformation have been calculated as >38 and >5.5, respectively. When these cut-off values are employed, the area under the curve (AUC) is > 0.8 for both, indicating that TRP metabolism in patients with FAP may be used to monitor and predict the tumorigenic evolution