Can previously sedentary females use the feeling scale to regulate exercise intensity in a gym environment? an observational study

Background Recent research suggests that the Feeling Scale (FS) can be used as a method of exercise intensity regulation to maintain a positive affective response during exercise. However, research to date has been carried out in laboratories and is not representative of natural exercise environments. The purpose of this study was to evaluate whether sedentary women can self-regulate their exercise intensity using the FS to experience positive affective responses in a gym environment using their own choice of exercise mode; cycling or treadmill. Methods Fourteen females (24.9 years ± 5.2; height 166.7 ± 5.7 cm; mass 66.3 ± 13.4 kg; BMI 24.1 ± 5.5)) completed a submaximal exercise test and each individual’s ventilatory threshold (V˙T) was identified. Following this, three 20 min gym-based exercise trials, either on a bike or treadmill were performed at an intensity that was self-selected and perceived to correspond to the FS value of +3 (good). Oxygen uptake, heart rate (HR) and ratings of perceived exertion (RPE) were measured during exercise at the participants chosen intensity. Results Results indicated that on average participants worked close to their V˙T and increased their exercise intensity during the 20-min session. Participants worked physiologically harder during cycling exercise. Consistency of oxygen uptake, HR and RPE across the exercise trials was high. Conclusion The data indicate that previously sedentary women can use the FS in an ecological setting to regulate their exercise intensity and that regulating intensity to feel ‘good’ should lead to individuals exercising at an intensity that would result in cardiovascular gains if maintained

Centrifuge modelling of screw piles for offshore wind energy foundations

Screw piles (helical piles) can provide a viable, cost-effective and low-noise installation alternative to increasing the size of existing foundation solutions (e.g. monopiles) to meet the demand for the advancement of offshore wind energy into deeper water. Significant upscaling of widely used onshore screw pile geometries will be required to meet the loading conditions of a jacket supported offshore wind turbine. This increase in size will lead to greater installation force and torque. This paper presents preliminary results from centrifuge tests investigating the requirements to install screw piles designed for an offshore wind energy application using specially developed equipment. Results indicate that the equipment is suitable to investigate these screw pile requirements and that significant force is required for such upscaled screw piles, with 19 MN vertical force and 7 MNm torque for the standard design. Optimisation of the screw pile geometry, reduced these forces by 29 and 11% for the vertical and rotational forces respectively

Effects of Folding on Laminated Dough

The purpose of this experiment is to determine the effect on volume, flakiness, and air cell size and amount in basic croissants when the dough is folded less than and more than what’s currently considered standard. The process of dough lamination, or the creation of alternating layers of dough and fat, is a technique used in various pastries. The layer of fat, often butter or margarine, creates an impenetrable barrier to the steam, or water vapor, produced by surrounding dough layers. This facilitates lift within the pastry and while many types don’t contain yeast, lamination becomes crucial to the finalized shape and volume of the product. The more layers of fat, the more supposed lift a pastry can undergo, however, as folds increase, the thinning of each fat layer also increases the likelihood of fracture or pooling together unevenly. Thus, too much fracturing can result in a loss of gas retention and lift as well as decrease the flakiness. Consequently, a balance must be found between too little and too many folds.1 The outlined experiment was performed using a classic French croissant recipe. Croissants with different numbers of folds were produced and analyzed in various ways including a subjective sensory panel to determine possible consumer perceptions. The industry standard of 3 folds, or 27 layers, was determined to be the most desirable. Fewer folds resulted in air cells that were much too big, and more folds resulted in non-uniform air cells and a doughy texture as well as a denser product overall

The strategic impacts of Intelligent Automation for knowledge and service work : An interdisciplinary review

We would like to thank Professor Jarvenpaa and the review team for all the constructive comments and suggestions that were most helpful in revising the paper and in offering a stronger contribution. We would also like to thank Professor Guy Fitzgerald for his constructive comments on earlier versions of the paper. This study was funded by the Chartered Institute of Professional Development (CIPD). The views expressed are those of the authors and not necessarily those of the CIPD.Peer reviewedPublisher PD

The impact of the internet of things on mobile workers

Ongoing developments in digital, computer, and communication technologies are likely to have profound long-term consequences for the nature of work and employment (Brynjolfsson & McAfee 2016). One significant area of development concerns the Internet of Things (IoT). The IoT can be described as everyday objects, such as cars, fridges or watches, having internet connectivity allowing them to send and receive data. The IoT is predicted to be a major IT-enabled business trend over the next 10 years. Peppet (2014) suggests the potential for 200 billion connected devices by 2020 and a trillion by 2025, and Mishra et al. (2016) note that according to McKinsey (2013), IoT has a potential global economic impact of $36 trillion. A recent Computing (2016) report indicates that in the UK, applications of the IoT in work settings are most likely to involve the use of tracking devices for internal deployment to achieve cost optimization. For example, an English county police force are deploying an IoT platform to create connected vehicles and 4G streaming cameras that are lightweight and wearable and can stream high definition video. Internet-connected police cars allow police officers to use laptops, mobile phones and tablet computers in their vehicles giving them access to important information while working remotely (Palmer, 2015). Thus, the IoT has the potential to have significant impacts on the organization and management of mobile workers. This study will examine the impact of IoT technologies on mobile work in UK organizations. The main emphasis of the project is to develop user-centric considerations of digital technologies to counterbalance techno-centric research on this topic: the users in this study are defined as both organizations and individual workers. This is partly because various concerns have been raised regarding surveillance implications of these technologies for workers (O’Connor, 2015). This exploratory study has two aims: 1) to understand organizational drivers for the adoption of IoT for mobile work; 2) to explore how IoT technologies impact on mobile workers

Social isolation and Social Media Consumption among Graduate students during COVID-19: An Examination using Social Comparison Theory.

The COVID-19 crisis transformed the way we communicate with each other. Pre-existing theoretical frameworks can build structure out of the chaos; social-interaction theory is one of these. During our social distancing and prior to the vaccine's arrival, physical distancing was adopted as the primary strategy to 'flatten the curve' of the virus's spread. The human desire to connect, however, led to increasing reliance on social-platform outlets. Yet meaningful communication in these forums is elusive and often results in unsatisfying interactions that lack the natural cadence of in-person communications. There is a need to reflect back on how and why our various styles of social-media consumption often paradoxically increase rather than ameliorate our feelings of social isolation. Following this overview, the authors will recommend ways to recognize and change such counterproductive patterns of online activity

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio

Concert recording 2021-11-07a

[Track 1]. La maniere de Shumann /Jean-Michel Defaye -- [Track 2]. Sang till lotta / Jan Sandstrom -- [Track 3]. Concertino in B♭ / Ernst Sachse -- [Track 4]. Nearer my God to thee for 9 celli / James Stevens -- [Track 5]. Ave Maria / Franz Biebl -- [Track 6]. Soundtrack for trombone / Brian Sadler

Les droits disciplinaires des fonctions publiques : « unification », « harmonisation » ou « distanciation ». A propos de la loi du 26 avril 2016 relative à la déontologie et aux droits et obligations des fonctionnaires

The production of tt‾ , W+bb‾ and W+cc‾ is studied in the forward region of proton–proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98±0.02 fb−1 . The W bosons are reconstructed in the decays W→ℓν , where ℓ denotes muon or electron, while the b and c quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions.The production of $t\overline{t}$, $W+b\overline{b}$ and $W+c\overline{c}$ is studied in the forward region of proton-proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98 $\pm$ 0.02 \mbox{fb}^{-1}. The $W$ bosons are reconstructed in the decays $W\rightarrow\ell\nu$, where $\ell$ denotes muon or electron, while the $b$ and $c$ quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions

Use of an Ethinyl Estradiol/Etonogestrel Vaginal Ring Alters Vaginal Microbial Communities in Women With HIV.

BACKGROUND: Human immunodeficiency virus 1 (HIV-1) antiretroviral therapy (ART) alters hormonal contraceptive levels delivered via intravaginal ring (IVR) in a regimen-specific manner. We explored the role of the IVR on vaginal microbial communities, vaginal short chain fatty acids (SCFAs), vaginal HIV shedding, and the effect of vaginal microbes on hormone concentrations in cisgender women with HIV (WWH). METHODS: Vaginal microbes were assessed by 16S RNA sequencing of weekly vaginal swabs, vaginal SCFA by mass spectrometry, HIV-1 shedding by nucleic acid amplification on vaginal aspirates, and bacterial vaginosis by Nugent scoring from 74 participants receiving an etonogestrel/ethinyl estradiol (ENG/EE) intravaginal ring while on no ART (n = 25), efavirenz-based ART (n = 25), or atazanavir-based ART (n = 24). RESULTS: At baseline, microbial communities of the 64 substudy eligible participants robustly classified as Lactobacillus crispatus-dominant (n = 8), Lactobacillus gasseri-dominant (n = 2), Lactobacillus iners-dominant (n = 17), or mixed anaerobic communities (n = 37). During IVR therapy, there was an increased probability of Lactobacillus-dominant community state types (CSTs) (odds ratio = 1.61, P = .04). Vaginal CSTs were associated with Nugent scores. Bacterial vaginosis-associated bacteria were associated with significantly higher and L. iners with lower Nugent scores (all P adjusted <.1). Lactic acid levels were correlated with the relative abundance of Lactobacillus species (r2 = 0.574; P < .001). Vaginal shedding of HIV-1 was less common in women with L. crispatus-dominant microbiomes (P = .04). Mixed anaerobic vaginal communities modulated EE concentrations in a regimen-specific manner. CONCLUSIONS: Combined ENG/EE IVR therapy was associated with an increase in Lactobacillus-dominant vaginal microbial communities in WWH and may benefit those with bacterial vaginosis. EE levels were altered by the vaginal microbiota