Frequency modulation demodulator threshold extension device

Threshold extension device for improving operating performance of frequency modulatioin demodulators by eliminating click-type noise impulse

Electronic device increases threshold sensitivity and removes noise from FM communications receiver

Threshold extension device connected between demodulator output and filter output minimizes clicking noise. Device consists of click-eliminating signal transfer channel with follow-and-hold circuit and detector for sensing click impulses. Final output consists of signal plus low level noise without high amplitude impulses

Cyclotrons as Drivers for Precision Neutrino Measurements

As we enter the age of precision measurement in neutrino physics, improved flux sources are required. These must have a well-defined flavor content with energies in ranges where backgrounds are low and cross section knowledge is high. Very few sources of neutrinos can meet these requirements. However, pion/muon and isotope decay-at-rest sources qualify. The ideal drivers for decay-at-rest sources are cyclotron accelerators, which are compact and relatively inexpensive. This paper describes a scheme to produce decay-at-rest sources driven by such cyclotrons, developed within the DAEdALUS program. Examples of the value of the high precision beams for pursuing Beyond Standard Model interactions are reviewed. New results on a combined DAEdALUS--Hyper-K search for CP-violation that achieve errors on the mixing matrix parameter of 4 degrees to 12 degrees are presented.Comment: This paper was invited by the journal Advances in High Energy Physics for their upcoming special issue on "Neutrino Masses and Oscillations," which will be published on the 100th anniversary of Pontecorvo's birt

Shuttle extravehicular activity signal processor pulse amplitude modulation decommutator

To provide data with long-term stability and accuracy, the pulse amplitude modulation (PAM) decommutator was synchronized to the PAM-return to zero wavetrain, and each channel was sampled with a common sample and hold circuit and digitized sequentially. The digital value of each channel was then scaled by the digital value of the calibration channels. The corrected digital value of each channel was stored for one complete frame and then transferred to the multiplexer-demultiplexer at a high rate in one block of serial digital data. A test model was built to demonstrate this design approach taken for the PAM decom and performance data was provided. The accuracies obtained with various signal to noise ratios are shown

Expression of a catalytically inactive mutant form of glutathione peroxidase 4 (Gpx4) confers a dominant-negative effect in male fertility.

The selenoenzyme Gpx4 is essential for early embryogenesis and cell viability for its unique function to prevent phospholipid oxidation. Recently, the cytosolic form of Gpx4 was identified as an upstream regulator of a novel form of non-apoptotic cell death, called ferroptosis, whereas the mitochondrial isoform of Gpx4 (mGpx4) was previously shown to be crucial for male fertility. Here, we generated and analyzed mice with targeted mutation of the active site selenocysteine (Sec) of Gpx4 (Gpx4_U46S). Mice homozygous for Gpx4_U46S died at the same embryonic stage (E7.5) as Gpx4-/- embryos as expected. Surprisingly, male mice heterozygous for Gpx4_U46S presented subfertility. Subfertility was manifested in a reduced number of litters from heterozygous breedings and an impairment of spermatozoa to fertilize oocytes in vitro. Morphologically, sperm isolated from heterozygous Gpx4_U46S mice revealed many structural abnormalities particularly in the spermatozoan midpiece due to improper oxidation and polymerization of sperm capsular proteins and malformation of the mitochondrial capsule surrounding and stabilizing sperm mitochondria. These findings are reminiscent of sperm isolated from selenium-deprived rodents or from mice specifically lacking mGpx4. Due to a strongly facilitated incorporation of Ser in the polypeptide chain as compared to Sec at the UGA codon, expression of the catalytically inactive Gpx4_U46S was found to be strongly increased. Since the stability of the mitochondrial capsule of mature spermatozoa depends on the moonlighting function of Gpx4 both as an enzyme oxidizing capsular protein thiols and being a structural protein, tightly controlled expression of functional Gpx4 emerges being key for full male fertility

The Zipf law for random texts with unequal probabilities of occurrence of letters and the Pascal pyramid

We model the generation of words with independent unequal probabilities of occurrence of letters. We prove that the probability $p(r)$ of occurrence of words of rank $r$ has a power asymptotics. As distinct from the paper published earlier by B. Conrad and M. Mitzenmacher, we give a brief proof by elementary methods and obtain an explicit formula for the exponent of the power law.Comment: 4 page

The structural properties of the multi-layer graphene/4H-SiC(000-1) system as determined by Surface X-ray Diffraction

We present a structural analysis of the multi-layer graphene-4HSiC(000-1}) system using Surface X-Ray Reflectivity. We show for the first time that graphene films grown on the C-terminated (000-1}) surface have a graphene-substrate bond length that is very short (0.162nm). The measured distance rules out a weak Van der Waals interaction to the substrate and instead indicates a strong bond between the first graphene layer and the bulk as predicted by ab-initio calculations. The measurements also indicate that multi-layer graphene grows in a near turbostratic mode on this surface. This result may explain the lack of a broken graphene symmetry inferred from conduction measurements on this system [C. Berger et al., Science 312, 1191 (2006)].Comment: 9 pages with 6 figure

A combined analysis of short-baseline neutrino experiments in the (3+1) and (3+2) sterile neutrino oscillation hypotheses

We investigate adding two sterile neutrinos to resolve the apparent tension existing between short-baseline neutrino oscillation results and CPT-conserving, four-neutrino oscillation models. For both (3+1) and (3+2) models, the level of statistical compatibility between the combined dataset from the null short-baseline experiments Bugey, CHOOZ, CCFR84, CDHS, KARMEN, and NOMAD, on the one hand; and the LSND dataset, on the other, is computed. A combined analysis of all seven short-baseline experiments, including LSND, is also performed, to obtain the favored regions in neutrino mass and mixing parameter space for both models. Finally, four statistical tests to compare the (3+1) and the (3+2) hypotheses are discussed. All tests show that (3+2) models fit the existing short-baseline data significantly better than (3+1) models.Comment: 16 pages, 15 figures. Added NOMAD data to the analysis, one statistical test, and two figures. References and text added. Version submitted to PR

Climate Variability and the Millennium Development Goal Hunger Target

Climate variability contributes significantly to poverty and food insecurity. Proactive approaches to managing climate variability within vulnerable rural communities and among institutions operating at community, sub-national, and national levels is a crucial step toward achieving the Millennium Development Goal of eradicating extreme poverty and hunger. Climate variability can impact a household's access to food by affecting subsistence production, income from primary production, local food prices, and sometimes the economy of an entire region. The risk of household food insecurity is determined by the success of livelihood strategies in the face of climate and other shocks. Across the economy, climate variability affects food security through its influence on investment, adoption of agricultural technology, aggregate production, market prices and economic development, and hence the ability of individuals, communities and nations to produce and purchase food. The impacts of climate variability are both ex post – losses that follow a climate shock — and ex ante — opportunity costs of conservative risk management responses to climatic uncertainty. The report summarizes the scientific basis, current methodology, and prospects for improving climate prediction at a seasonal time scale. Current forecast methods give modest to moderately-high prediction skill in "hunger hotspots" in East, West and Southern Africa, and other regions in the tropics and subtropics. Applications of climate information contribute to a comprehensive strategy to combat hunger. First is the use of seasonal climate prediction in early warning systems to guide interventions to avert food crises. Second is the use of climate information to manage risk in agricultural systems within vulnerable rural communities and among a range of institutions. This includes smallholder farmers who comprise the largest group of poor and food-insecure; intermediary institutions that interface with farmers, and can provide the information, technical guidance and production inputs required for effective climate risk management; and institutions that make climate-sensitive decisions at a broader scale that influence food security. We also discuss measures to strengthen institutional capacity and coordination to improve management of climate variability. Improved management of climate variability has appealing synergies with other interventions that target hunger, including soil fertility management, small-scale water management, markets, and extension and communication systems