24 research outputs found

    Reviews

    Get PDF
    Steve McDowell and Phil Race, 500 Computing Tips for Trainers, London: Kogan Page, ISBN: 0–7494–2675–6. Paperback, 160 pages, £15.99

    Animal bones [from Nebelivka]

    Get PDF
    In this book, a team of international authors examines the hypothesis of independent Eastern European urbanism using the evidence gathered from the multi-disciplinary investigation of the Trypillia megasite of Nebelivka

    Reviews

    No full text
    Training in information technology (IT) is becoming a crucial activity for virtually all organizations - a well-worn cliche. Sadly, however, it is all too often the case that training budgets are manipulated and absorbed into other 'worthy' causes. The result is that IT training is hastily passed onto junior members of a team or to postgraduate students who have had little formal training and experience of IT training. It is for these novice trainers that the '500 computer tips' will be particularly useful but it is also a highly worthwhile, accessible reference for more experienced trainers in both academic and non-academic environments. This book (one of a series of '500 Tips' from Kogan Page) does not aim to give technical information about any particular software package but provides readable, understandable generic tips which have a sound pedagogical base (although this is carefully hidden)

    Reviews

    No full text
    As a result of various paradigm shifts, the World Wide Web (the Web) is changing both what we teach and how we teach it. Consequently, from the point of view of distributing resources, we are now experiencing a significant change of emphasis - from instructor push towards student pull. Web-Teaching is a book about teaching, especially interactive teaching, using the Web as a communications medium. It deals with the kinds of hardware, software and networks commonly used on the Web to deliver and support instruction and learning. Overall, it has two basic thrusts: first, it gives descriptions of what is possible on the Web; second, it identifies instructional strategies that are likely to be effective

    Broad HIV epitope specificity and viral inhibition induced by multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults

    Get PDF
    A correlation between in vivo and in vitro virus control mediated by CD8+ T-cell populations has been demonstrated by CD8 T-cell-mediated inhibition of HIV-1 and SIV replication in vitro in peripheral blood mononuclear cells (PBMCs) from infected humans and non-human primates (NHPs), respectively. Here, the breadth and specificity of T-cell responses induced following vaccination with replication-defective adenovirus serotype 35 (Ad35) vectors containing a fusion protein of Gag, reverse transcriptase (RT), Integrase (Int) and Nef (Ad35-GRIN) and Env (Ad35-ENV), derived from HIV-1 subtype A isolates, was assessed in 25 individuals. The vaccine induced responses to a median of 4 epitopes per vaccinee. We correlated the CD8 responses to conserved vs. variable regions with the ability to inhibit a panel of 7 HIV-1 isolates representing multiple clades in a virus inhibition assay (VIA). The results indicate that targeting immunodominant responses to highly conserved regions of the HIV-1 proteome may result in an increased ability to inhibit multiple clades of HIV-1 in vitro. The data further validate the use of the VIA to screen and select future HIV vaccine candidates. Moreover, our data suggest that future T cell-focused vaccine design should aim to induce immunodominant responses to highly conserved regions of the virus
    corecore