33 research outputs found
Mechanisms of the social control of children and young people: From âstop and searchâ to âstop and engageâ in Police Scotland
Since the implementation of stop and search reform in Scotland, the volume of this tactic has decreased and proportionality has increased. However, little has been published that has detailed the design, communication and implementation of stop and search reform in Scotland. This article traces the policy intentions of this reform programme and demonstrates that these aligned with central tenets of procedural justice theory. This article then examines ethnographic data regarding the dissemination and implementation of reform into police practice between 2016 and 2018, which demonstrates that the procedural justice intentions of reform to improve the policing of Scotlandâs children and young people were not reproduced in practice. Instead, reform paved the way for the emergence of a new and unscrutinised practice that came to be known as âstop and engageâ that has enabled the continued antagonistic and over-policing of young people in the post-reform environment
âFree text is essentially the enemy of what weâre trying to achieveâ: the framing of a national vision for delivering digital police contact
Police organisations in England and Wales, as in many other contexts, are increasingly shifting crime reporting and other public-facing contact online. In this paper we explore the beliefs, motivations, and objectives of those tasked with âdeliveringâ the âvisionâ of digital police contact at the strategic national level. We use Goffmanâs concept of frames â the set of expectations an actor brings to a situation or process â to understand how participants enacted this 'channel shiftâ (Wells et al., 2023), the ends they were seeking to meet, and how different interests came to be designed-in to the contact architecture. We suggest that the primary frame centred around notions of efficiency and demand management. Running alongside this is a secondary frame of customer service, where it is assumed that the public also wish for the efficient delivery of this technologically mediated service. This, we suggest, is likely to be only a partial reflection of what people want when contacting police; but the framing of 'contactâ as a separate deliverable by those delivering this agenda serves to occlude or evade this point. Technology, we argue, imprints itself on the context by appearing to offer a convenient solution to problems of public wants and police needs
âChannel Shiftâ:technologically-mediated policing and procedural justice
In recent years, police forces in the United Kingdom have introduced various technologies that alter the methods by which they interact with the public. In a parallel development, many forces have also begun to embrace the concept of procedural justice as a method through which to secure legitimacy and (in turn) public compliance and cooperation. What has not received sufficient attention, within policing or academia, is the extent to which these two trends are compatible, with the procedural justice literature still predicated on an assumption that policeâpublic âcontactsâ or âencountersâ are in-person. The effect of technologically mediating policeâpublic contacts on âpolicing by consentâ, is therefore unknown. In this article, we focus specifically on the possible implications of the Single Online Home (SOH) (a portal through which the public can report crime, get updates on cases, give feedback and pay fines, among other things, which is currently being rolled out across forces), considering âinteractionsâ between police and public where there is no physical co-presence. Noting the unique context that is policing, we draw on the limited existing research on procedural justice encounters in technologically mediated contexts to explore whether procedural justice theory is âfuture-proofâ for a policing context increasingly reliant on such encounters. We conclude that, through empirical research, we must update our conceptual understanding of what âcontactâ can mean, and accept that current developments may in fact be transforming relationships rather than simply facilitating existing ones
âChannel shiftâ: Technologically mediated policing and procedural justice
In recent years, police forces in the United Kingdom have introduced various technologies that alter the methods by which they interact with the public. In a parallel development, many forces have also begun to embrace the concept of procedural justice as a method through which to secure legitimacy and (in turn) public compliance and cooperation. What has not received sufficient attention, within policing or academia, is the extent to which these two trends are compatible, with the procedural justice literature still predicated on an assumption that policeâpublic âcontactsâ or âencountersâ are in-person. The effect of technologically mediating policeâpublic contacts on âpolicing by consentâ, is therefore unknown. In this article, we focus specifically on the possible implications of the Single Online Home (SOH) (a portal through which the public can report crime, get updates on cases, give feedback and pay fines, among other things, which is currently being rolled out across forces), considering âinteractionsâ between police and public where there is no physical co-presence. Noting the unique context that is policing, we draw on the limited existing research on procedural justice encounters in technologically mediated contexts to explore whether procedural justice theory is âfuture-proofâ for a policing context increasingly reliant on such encounters. We conclude that, through empirical research, we must update our conceptual understanding of what âcontactâ can mean, and accept that current developments may in fact be transforming relationships rather than simply facilitating existing ones
âChannel Shiftâ: technologically-mediated policing and procedural justice
In recent years, police forces in the United Kingdom have introduced various technologies that alter the methods by which they interact with the public. In a parallel development, many forces have also begun to embrace the concept of procedural justice as a method through which to secure legitimacy and (in turn) public compliance and cooperation. What has not received sufficient attention, within policing or academia, is the extent to which these two trends are compatible, with the procedural justice literature still predicated on an assumption that policeâpublic âcontactsâ or âencountersâ are in-person. The effect of technologically mediating policeâpublic contacts on âpolicing by consentâ, is therefore unknown. In this article, we focus specifically on the possible implications of the Single Online Home (SOH) (a portal through which the public can report crime, get updates on cases, give feedback and pay fines, among other things, which is currently being rolled out across forces), considering âinteractionsâ between police and public where there is no physical co-presence. Noting the unique context that is policing, we draw on the limited existing research on procedural justice encounters in technologically mediated contexts to explore whether procedural justice theory is âfuture-proofâ for a policing context increasingly reliant on such encounters. We conclude that, through empirical research, we must update our conceptual understanding of what âcontactâ can mean, and accept that current developments may in fact be transforming relationships rather than simply facilitating existing ones
AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders.
AMPA receptors (AMPARs) are tetrameric ligand-gated channels made up of combinations of GluA1-4 subunits encoded by GRIA1-4 genes. GluA2 has an especially important role because, following post-transcriptional editing at the Q607 site, it renders heteromultimeric AMPARs Ca2+-impermeable, with a linear relationship between current and trans-membrane voltage. Here, we report heterozygous de novo GRIA2 mutations in 28 unrelated patients with intellectual disability (ID) and neurodevelopmental abnormalities including autism spectrum disorder (ASD), Rett syndrome-like features, and seizures or developmental epileptic encephalopathy (DEE). In functional expression studies, mutations lead to a decrease in agonist-evoked current mediated by mutant subunits compared to wild-type channels. When GluA2 subunits are co-expressed with GluA1, most GRIA2 mutations cause a decreased current amplitude and some also affect voltage rectification. Our results show that de-novo variants in GRIA2 can cause neurodevelopmental disorders, complementing evidence that other genetic causes of ID, ASD and DEE also disrupt glutamatergic synaptic transmission
Development of a Unifying Target and Consensus Indicators for Global Surgical Systems Strengthening: Proposed by the Global Alliance for Surgery, Obstetric, Trauma, and Anaesthesia Care (The G4 Alliance)
After decades on the margins of primary health care, surgical and anaesthesia care is gaining increasing priority within the global development arena. The 2015 publications of the Disease Control Priorities third edition on Essential Surgery and the Lancet Commission on Global Surgery created a compelling evidenced-based argument for the fundamental role of surgery and anaesthesia within cost-effective health systems strengthening global strategy. The launch of the Global Alliance for Surgical, Obstetric, Trauma, and Anaesthesia Care in 2015 has further coordinated efforts to build priority for surgical care and anaesthesia. These combined efforts culminated in the approval of a World Health Assembly resolution recognizing the role of surgical care and anaesthesia as part of universal health coverage. Momentum gained from these milestones highlights the need to identify consensus goals, targets and indicators to guide policy implementation and track progress at the national level. Through an open consultative process that incorporated input from stakeholders from around the globe, a global target calling for safe surgical and anaesthesia care for 80% of the world by 2030 was proposed. In order to achieve this target, we also propose 15 consensus indicators that build on existing surgical systems metrics and expand the ability to prioritize surgical systems strengthening around the world
A Solve-RD ClinVar-based reanalysis of 1522 index cases from ERN-ITHACA reveals common pitfalls and misinterpretations in exome sequencing
Purpose
Within the Solve-RD project (https://solve-rd.eu/), the European Reference Network for Intellectual disability, TeleHealth, Autism and Congenital Anomalies aimed to investigate whether a reanalysis of exomes from unsolved cases based on ClinVar annotations could establish additional diagnoses. We present the results of the âClinVar low-hanging fruitâ reanalysis, reasons for the failure of previous analyses, and lessons learned.
Methods
Data from the first 3576 exomes (1522 probands and 2054 relatives) collected from European Reference Network for Intellectual disability, TeleHealth, Autism and Congenital Anomalies was reanalyzed by the Solve-RD consortium by evaluating for the presence of single-nucleotide variant, and small insertions and deletions already reported as (likely) pathogenic in ClinVar. Variants were filtered according to frequency, genotype, and mode of inheritance and reinterpreted.
Results
We identified causal variants in 59 cases (3.9%), 50 of them also raised by other approaches and 9 leading to new diagnoses, highlighting interpretation challenges: variants in genes not known to be involved in human disease at the time of the first analysis, misleading genotypes, or variants undetected by local pipelines (variants in off-target regions, low quality filters, low allelic balance, or high frequency).
Conclusion
The âClinVar low-hanging fruitâ analysis represents an effective, fast, and easy approach to recover causal variants from exome sequencing data, herewith contributing to the reduction of the diagnostic deadlock