Is world view neutral education possible and desirable? : A Christian response to liberal arguments.

The main object of this thesis is to find out why it so often is assumed that education can and should be neutral between world views, and to argue against this. It is also discussed what the world view basis of the common school should be when neutrality is impossible. The idea of a common school that inculcates common values without taking a stand between different religions and secular world views, is central in today's idea of liberal education. It is argued here that however thin the common basis for the school is, certain world view presuppositions will always be conveyed, at least implicitly. It is easier to see the world view presuppositions in one account of education if it is contrasted with another. An account is given of Christian education, emphasizing its view of reality and human nature, the meaning of life and the corresponding purpose of education. Contrasted with this, an analysis of J. White's and K. Strike's accounts of education based on common values only, shows that they both convey world view presuppositions that are incompatible with a Christian view and therefore not neutral. The argument of incompatibility is strengthened by a discussion of T. H. McLaughlin's three different accounts of common, world view neutral education, Catholic education, and liberal religious education. Several kinds of argument for the possibility and desirability of world view neutral education are analysed, and it is claimed that none of them is valid. Some imply a shallow understanding of religion, others a biased view of education. It is argued that liberal education in many ways is more likely to indoctrinate than Christian education IS. Finally, it is argued that it is desirable to have Christian education in state schools, and the degree to which this is possible is discussed

Additional file 1: of Discordant lymphoma consisting of mediastinal large B-cell lymphoma and nodular sclerosis Hodgkin lymphoma in the right supraclavicular lymph nodes: a case report

Gene rearrangements and clonality analysis of immunoglobulin heavy chain gene, Kappa light chain gene, and Lambda light chain gene were identified in mediastinal large B-cell lymphoma and in nodular sclerosis Hodgkin lymphoma in the right supraclavicular lymph nodes using the IdentiCloneTM IGH/IGK/IGL Gene Clonality Assay (InVivoScribe Technologies, CA, USA). (TIF 1129 kb

Construction of an Ultrasensitive Molecularly Imprinted Virus Sensor Based on an “Explosive” Secondary Amplification Strategy for the Visual Detection of Viruses

Viral outbreaks have caused great disruptions to the economy and public health in recent years. The accurate detection of viruses is a key factor in controlling and overcoming epidemics. In this study, an ultrasensitive molecularly imprinted virus sensor was developed based on an “explosive” secondary amplification strategy. Magnetic particles coated with carbon quantum dots (Fe3O4@CDs) were used as carriers and fluorescent probes, while aptamers were introduced into the imprinting layer to enhance the specific recognition of the target virus enterovirus 71 (EV71). When EV71 was captured by the imprinted particles, the fluorescence of the CDs was quenched, especially after binding to the aptamer-modified ZIF-8 loaded with a large amount of phenolphthalein, thereby resulting in signal amplification. Then, when adjusting the pH of the solution to 12, the decomposition of ZIF-8 released phenolphthalein, which turned the solution red, leading to the second “explosive” amplification of the signal. Therefore, the detection of EV71 with ultrasensitivity was achieved, which allows for visual detection by the naked eye in the absence of any instruments. The detection limits for fluorescence and visualization detection were 8.33 fM and 2.08 pM, respectively. In addition, a satisfactory imprinting factor of 5.4 was achieved, and the detection time only needed 20 min. It is expected that this fluorescence-colorimetric dual-mode virus molecularly imprinted sensor will show excellent prospects in epidemic prevention and rapid clinical diagnosis

Data_Sheet_1_KMT2C mutation is a diagnostic molecular marker for primary thyroid osteosarcoma: A case report and literature review.DOCX

Primary thyroid osteosarcoma is an extremely rare tumor which is associated with a poor prognosis. In this study, we describe an additional case. A 4.5 × 3.8 cm irregular heterogeneous nodule was examined in the left thyroid gland of a 72-year-old woman. Cytological smears and histopathological specimens showed typical features of osteosarcoma with a neoplastic lesion rich in spindle cells with occasional multinucleated cells and lace-like osteoid matrix. Negative immunoreaction with epithelial markers and positive immunoreaction with SATB2 and low Ki-67 labeling index suggested the diagnosis of osteosarcoma. Multiple KMT2C gene mutations determined by next-generation sequencing further confirmed the diagnosis.</p

Additional file 3 of The genetic variation in drought resistance in eighteen perennial ryegrass varieties and the underlying adaptation mechanisms

Supplementary Material

Additional file 2 of The genetic variation in drought resistance in eighteen perennial ryegrass varieties and the underlying adaptation mechanisms

Supplementary Material

Ratiometric Fluorescence Sensor for the MicroRNA Determination by Catalyzed Hairpin Assembly

A novel catalyzed hairpin assembly-based turn-on ratiometric fluorescence biosensor was constructed for the determination of microRNA-122 (miRNA-122) by using 2-aminopurine (2-AP) and thioflavin T (ThT) as detection signal sources. Hairpin DNA sequence (H1) includes the complementary strands of miRNA-122 and G-quadruplex-forming sequence. When miRNA-122 was presented, hybridization occurred between miRNA-122 and part of H1, causing a double-stranded DNA and a G-quadruplex formed. The formed double-stranded DNA significantly decreased the fluorescence intensity of 2-AP. Furthermore, after binding with ThT, the formed G-quadruplex led to the fluorescent enhancement. The hairpin DNA sequence (H2) hybridized with the unfolded H1 and displaced miRNA-122. Finally, the displaced miRNA-122 again hybridized with the H1 and initiated cycle amplification. This sensor showed a linear ranges of 0.5–50 nM and the limit of detection for miRNA-122 assay was 72 pM (with the lowest measured concentration of 500 pM) for determination of miRNA-122 when no other miRNA was present. Measurements on cell lysates from 100, 1000, and 10 000 cells of three different cell lines provided increasing signal ratios, which showed the application potential of the sensor for miRNA determination in real samples

Additional file 4 of The genetic variation in drought resistance in eighteen perennial ryegrass varieties and the underlying adaptation mechanisms

Supplementary Material

Additional file 1 of The genetic variation in drought resistance in eighteen perennial ryegrass varieties and the underlying adaptation mechanisms

Supplementary Material

Additional file 5 of The genetic variation in drought resistance in eighteen perennial ryegrass varieties and the underlying adaptation mechanisms

Supplementary Material