4 research outputs found

    Analysis of case-control study type I error rates from 3 simulated SNPs within <i>BDNF</i>.

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    <p>The three SNPs show allele frequency differences between CEU and YRI of 0.066 (rs11030108), 0.102 (rs10767658), and 0.233 (rs1013402). The y-axis is estimated type I error rate versus the simulated CEU proportion (x-axis). Panels on the left show data with a difference in disease prevalence ratio of 1.25 while a ratio of 1.5 is shown on the right.</p

    Estimated odds ratios (OR) from case-control analysis of 3 simulated SNPs within <i>BDNF</i>.

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    <p>Conventions are the same as <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0019699#pone-0019699-g002" target="_blank">Figure 2</a> except the y-axis is the average estimated OR from the same analysis as presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0019699#pone-0019699-g002" target="_blank">Figure 2</a>.</p

    Detection of population structure in four HapMap populations.

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    <p>The first two principal components from EIGENSTRAT are plotted for all 3 SNP panels (A, SNP panel 93; B, SNP panel 52; C, SNP panel 19). As more AIMs are used in the analysis, the resolution improves. The 52 SNP panel appears to have some overlap between CEU and CHB+JPT though it should be noted that these datapoints are more clearly differentiated by considering the third and fourth principal components (not shown).</p

    Descriptive statistics on the number of identical genotypes between all possible pairing of samples by group.

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    <p>Descriptive statistics on the number of identical genotypes between all possible pairing of samples by group.</p
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