309 research outputs found
Experiences in wetland co-management: the MACH project
Wetlands, Fishery management
Persistent currents with long-range hopping in 1D single-isolated-diffusive rings
We show from exact calculations that a simple tight-binding Hamiltonian with
diagonal disorder and long-range hopping integrals, falling off as a power
of the inter-site separation, correctly describes the experimentally
observed amplitude (close to the value of an ordered ring) and flux-periodicity
() of persistent currents in single-isolated-diffusive normal metal rings
of mesoscopic size. Long-range hopping integrals tend to delocalize the
electrons even in the presence of disorder resulting orders of magnitude
enhancement of persistent current relative to earliar predictions.Comment: 4 pages, 3 figure
Strange behavior of persistent currents in small Hubbard rings
We show exactly that small Hubbard rings exhibit unusual kink-like structures
giving anomalous oscillations in persistent current. Singular behavior of
persistent current disappears in some cases. In half-filled systems mobility
gradually drops to zero with interaction, while it converges to some finite
value in non-half-filled cases.Comment: 7 pages, 6 figure
On the role of electron correlation and disorder on persistent currents in isolated one-dimensional rings
To understand the role of electron correlation and disorder on persistent
currents in isolated 1D rings threaded by magnetic flux , we study the
behavior of persistent currents in aperiodic and ordered binary alloy rings.
These systems may be regarded as disordered systems with well-defined
long-range order so that we do not have to perform any configuration averaging
of the physical quantities. We see that in the absence of interaction, disorder
suppresses persistent currents by orders of magnitude and also removes its
discontinuity as a function of . As we introduce electron correlation, we
get enhancement of the currents in certain disordered rings. Quite
interestingly we observe that in some cases, electron correlation produces
kink-like structures in the persistent current as a function of . This
may be considered as anomalous Aharonov-Bohm oscillations of the persistent
current and recent experimental observations support such oscillations. We find
that the persistent current converges with the size of the rings.Comment: 9 pages, 8 figure
Self-optimization, community stability, and fluctuations in two individual-based models of biological coevolution
We compare and contrast the long-time dynamical properties of two
individual-based models of biological coevolution. Selection occurs via
multispecies, stochastic population dynamics with reproduction probabilities
that depend nonlinearly on the population densities of all species resident in
the community. New species are introduced through mutation. Both models are
amenable to exact linear stability analysis, and we compare the analytic
results with large-scale kinetic Monte Carlo simulations, obtaining the
population size as a function of an average interspecies interaction strength.
Over time, the models self-optimize through mutation and selection to
approximately maximize a community fitness function, subject only to
constraints internal to the particular model. If the interspecies interactions
are randomly distributed on an interval including positive values, the system
evolves toward self-sustaining, mutualistic communities. In contrast, for the
predator-prey case the matrix of interactions is antisymmetric, and a nonzero
population size must be sustained by an external resource. Time series of the
diversity and population size for both models show approximate 1/f noise and
power-law distributions for the lifetimes of communities and species. For the
mutualistic model, these two lifetime distributions have the same exponent,
while their exponents are different for the predator-prey model. The difference
is probably due to greater resilience toward mass extinctions in the food-web
like communities produced by the predator-prey model.Comment: 26 pages, 12 figures. Discussion of early-time dynamics added. J.
Math. Biol., in pres
The analysis of predictability of alpha-decay half-life formulae and the alpha partial half-lives of some exotic nuclei
The predictabilities of the three alpha-decay half-life formulae, the Royer
GLDM, the Viola-Seaborg and the Sobiczewski-Parkhomenko formulae, have been
evaluated by developing a method based on the ansatz of standard experimental
benchmarking. The coefficients of each formula were re-derived using the
reliable data of the alpha-standards nuclei. The modified formulae that
resulted were used to evaluate the accuracies of the formulae towards the
prediction of half-lives of a set of nuclides with well-studied alpha-
spectroscopic data as well as a set of exotic alpha-emitters. Further, a simple
linear optimization of the modified formulae allowed adjustments for the
insufficient statistics of the primary data set without changing the modified
formulae. While the three modified formulae showed equivalent results for all
the medium heavy nuclei except the odd-odd, the modified GLDM showed relatively
the best figures of merit for the odd-odd and superheavy nuclides.Comment: 16 pages, 4 tables, 2 figure
A Diffractive Study of Parametric Process in Nonlinear Photonic Crystals
We report a general description of quasi-phase-matched parametric process in
nonlinear photonic crystals (NLPC) by extending the conventional X-ray
diffraction theory in solids. Under the virtual wave approximation,
phase-matching resonance is equivalent to the diffraction of the scattered
virtual wave. Hence a modified NLPC Ewald construction can be built up, which
illustrates the nature of the accident for the diffraction of the virtual wave
in NLPC and further reveals the complete set of diffractions of the virtual
wave for both of the air-dielectric and dielectric-dielectric contacts. We show
the two basic linear sequences, the anti-stacking and para-stacking linear
sequences, in one-dimension (1D) NLPC and present a general rule for multiple
phase-matching resonances in 1D NLPC. The parameters affecting the NLPC
structure factor are investigated, which indicate that not only the Ewald
construction but also the relative NLPC atom size together determine whether a
diffraction of the virtual wave can occur in 2D NLPC. The results also show
that 1D NLPC is a better choice than 2D NLPC for a single parametric process
Modeling Translation in Protein Synthesis with TASEP: A Tutorial and Recent Developments
The phenomenon of protein synthesis has been modeled in terms of totally
asymmetric simple exclusion processes (TASEP) since 1968. In this article, we
provide a tutorial of the biological and mathematical aspects of this approach.
We also summarize several new results, concerned with limited resources in the
cell and simple estimates for the current (protein production rate) of a TASEP
with inhomogeneous hopping rates, reflecting the characteristics of real genes.Comment: 25 pages, 7 figure
Spatially resolved multiomics of human cardiac niches
The function of a cell is defined by its intrinsic characteristics and its niche: the tissue microenvironment in which it dwells. Here we combine single-cell and spatial transcriptomics data to discover cellular niches within eight regions of the human heart. We map cells to microanatomical locations and integrate knowledge-based and unsupervised structural annotations. We also profile the cells of the human cardiac conduction system1. The results revealed their distinctive repertoire of ion channels, G-protein-coupled receptors (GPCRs) and regulatory networks, and implicated FOXP2 in the pacemaker phenotype. We show that the sinoatrial node is compartmentalized, with a core of pacemaker cells, fibroblasts and glial cells supporting glutamatergic signalling. Using a custom CellPhoneDB.org module, we identify trans-synaptic pacemaker cell interactions with glia. We introduce a druggable target prediction tool, drug2cell, which leverages single-cell profiles and drug-target interactions to provide mechanistic insights into the chronotropic effects of drugs, including GLP-1 analogues. In the epicardium, we show enrichment of both IgG+ and IgA+ plasma cells forming immune niches that may contribute to infection defence. Overall, we provide new clarity to cardiac electro-anatomy and immunology, and our suite of computational approaches can be applied to other tissues and organs
Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018
Anemia is a globally widespread condition in women and is associated with reduced economic productivity and increased mortality worldwide. Here we map annual 2000–2018 geospatial estimates of anemia prevalence in women of reproductive age (15–49 years) across 82 low- and middle-income countries (LMICs), stratify anemia by severity and aggregate results to policy-relevant administrative and national levels. Additionally, we provide subnational disparity analyses to provide a comprehensive overview of anemia prevalence inequalities within these countries and predict progress toward the World Health Organization’s Global Nutrition Target (WHO GNT) to reduce anemia by half by 2030. Our results demonstrate widespread moderate improvements in overall anemia prevalence but identify only three LMICs with a high probability of achieving the WHO GNT by 2030 at a national scale, and no LMIC is expected to achieve the target in all their subnational administrative units. Our maps show where large within-country disparities occur, as well as areas likely to fall short of the WHO GNT, offering precision public health tools so that adequate resource allocation and subsequent interventions can be targeted to the most vulnerable populations.Peer reviewe
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