Incidence and hazard ratios for atypical and typical pneumonia in the COPD with asthma cohort and COPD cohort stratified by sex, age group, and comorbidity in the age-and-sex-matched cohorts.

Incidence and hazard ratios for atypical and typical pneumonia in the COPD with asthma cohort and COPD cohort stratified by sex, age group, and comorbidity in the age-and-sex-matched cohorts.</p

Adjusted hazard ratios for atypical and typical pneumonia in COPD with asthma cohort with and without ICSs and OSs use during the follow-up period by age-and-sex-matched.

Adjusted hazard ratios for atypical and typical pneumonia in COPD with asthma cohort with and without ICSs and OSs use during the follow-up period by age-and-sex-matched.</p

Health care and antibiotics utilization among children in 3 study groups: Vesicoureteral reflux (VUR), urinary tract infection (UTI) and VUR & UTI.

Health care and antibiotics utilization among children in 3 study groups: Vesicoureteral reflux (VUR), urinary tract infection (UTI) and VUR & UTI.</p

Demographic characteristics of stage III breast cancer patients who received surgery in Taiwan (2010–2017).

Demographic characteristics of stage III breast cancer patients who received surgery in Taiwan (2010–2017).</p

Demographics among the 4 cohorts: Vesicoureteral reflux (VUR) cohort, urinary tract infection (UTI) cohort, VUR and UTI cohort, and control cohort.

Demographics among the 4 cohorts: Vesicoureteral reflux (VUR) cohort, urinary tract infection (UTI) cohort, VUR and UTI cohort, and control cohort.</p

Incidence, crude and adjusted hazard ratio of asthma among children with vesicoureteral reflux (VUR) stratified by specific treatments for VUR in Cox proportional hazard regression.

Incidence, crude and adjusted hazard ratio of asthma among children with vesicoureteral reflux (VUR) stratified by specific treatments for VUR in Cox proportional hazard regression.</p

S2 Fig -

BackgroundPatients diagnosed with stage III breast cancer often undergo surgery, radiation therapy, and chemotherapy as part of their treatment. The choice of anesthesia technique during surgery has been a subject of interest due to its potential association with immune changes and prognosis. In this study, we aimed to compare the mortality rates between stage III breast cancer patients undergoing surgery with propofol-based intravenous general anesthesia and those receiving inhaled anesthetics.MethodsUsing data from Taiwan’s National Health Insurance Research Database and Taiwan Cancer Registry, we identified a cohort of 10,896 stage III breast cancer patients. Among them, 1,506 received propofol-based intravenous anesthetic maintenance, while 9,390 received inhaled anesthetic maintenance. To ensure comparability between the two groups, we performed propensity-score matching.ResultsOur findings revealed a significantly lower mortality rate in patients who received inhaled anesthetics compared to those who received propofol-based intravenous anesthesia. Sensitivity analysis further confirmed the robustness of our results.ConclusionsThis study suggests that inhaled anesthesia technique is associated with a lower mortality rate in clinical stage III breast cancer. Further research is needed to validate and expand upon these results.</div

S3 Fig -

BackgroundPatients diagnosed with stage III breast cancer often undergo surgery, radiation therapy, and chemotherapy as part of their treatment. The choice of anesthesia technique during surgery has been a subject of interest due to its potential association with immune changes and prognosis. In this study, we aimed to compare the mortality rates between stage III breast cancer patients undergoing surgery with propofol-based intravenous general anesthesia and those receiving inhaled anesthetics.MethodsUsing data from Taiwan’s National Health Insurance Research Database and Taiwan Cancer Registry, we identified a cohort of 10,896 stage III breast cancer patients. Among them, 1,506 received propofol-based intravenous anesthetic maintenance, while 9,390 received inhaled anesthetic maintenance. To ensure comparability between the two groups, we performed propensity-score matching.ResultsOur findings revealed a significantly lower mortality rate in patients who received inhaled anesthetics compared to those who received propofol-based intravenous anesthesia. Sensitivity analysis further confirmed the robustness of our results.ConclusionsThis study suggests that inhaled anesthesia technique is associated with a lower mortality rate in clinical stage III breast cancer. Further research is needed to validate and expand upon these results.</div

Comparison of overall mortality rate in stage III breast cancer patients considering different baseline characteristics, after adjusting for age, sex, comorbidities, and medications before propensity score matching.

Comparison of overall mortality rate in stage III breast cancer patients considering different baseline characteristics, after adjusting for age, sex, comorbidities, and medications before propensity score matching.</p

Incidence and hazard ratios for atypical and typical pneumonia in patients with and without COPD with asthma cohort by age-and-sex-matched.

Incidence and hazard ratios for atypical and typical pneumonia in patients with and without COPD with asthma cohort by age-and-sex-matched.</p