Patient characteristics.

<p>Data are median (interquartile range) or number (%).</p><p>Abbreviations: GCS: Glasgow Coma Scale; IL-6: interleukin-6; mRS: modified Rankin Scale; WBC: white blood cell count.</p><p>Patient characteristics.</p

Adjusted associations between plasma IL-6 levels and poor 30-day outcome.

<p>*: Adjusted for dichotomized age, Glasgow Coma Scale on day 0, and vasospasm and Fisher grades according to the receiver operating characteristic analyses.</p><p>Abbreviations: IL-6: interleukin-6; mRS: modified Rankin Scale.</p><p>Adjusted associations between plasma IL-6 levels and poor 30-day outcome.</p

ROC analyses of the risk factors for predicting 30-day outcome.

<p>*: Data in parentheses are 95% confidence intervals.</p><p>^†: Sensitivity and specificity for predicting poor 30-day outcome. Data in parentheses are numbers used to calculate percentages.</p><p>Abbreviations: GCS: Glasgow Coma Scale; IL-6: interleukin-6.</p><p>ROC analyses of the risk factors for predicting 30-day outcome.</p

Correlations between aneurysmal IL-6 level and other characteristics.

<p>*: Spearman's rank correlation test.</p><p>Abbreviations: GCS: Glasgow Coma Scale; IL-6: interleukin-6; WBC: white blood cell count.</p><p>Correlations between aneurysmal IL-6 level and other characteristics.</p

The relationship between serum iron and interleukin-6 levels in all subjects.

<p>(Dependent variable: serum iron concentration).</p><p>*<i>P</i><0.05 and **<i>P</i><0.001, general linear model. AMI, acute myocardial infarction; IL-6, interleukin 6; SE, standardized error. The intercept is the predicted value of serum iron concentration in AMI group. The predicted value is 71.872 µg/dl. The serum iron concentration in the control group was, on average, 35.494 µg/dl higher than that in the AMI group. For every one unit increase in IL-6 concentration, there was a decrease of 0.625 units in serum iron concentration.</p

Univariate correlation between serum iron concentration and patient characteristics after acute myocardial infarction.

<p>*<i>P</i><0.05, Spearman’s rho correlation.6 M, six months; TIMI, thrombolysis in myocardial infarction; EF 6 M, left ventricular ejection fraction at 6–month follow-up.</p

The relationship between serum iron concentration and IL-6 levels in all enrolled subjects.

<p>The result indicated that the serum iron concentration was negatively correlated with circulating IL-6 concentration in all study subjects. The linear relationship was well described by Serum iron = 95.994−1.246 (IL-6), R² = 0.133 and <i>P</i><0.001.</p

Characteristics of patients grouped by change in left ventricular ejection fraction 6 months after percutaneous coronary interventions for acute myocardial infarction.

<p>*<i>P</i><0.05, Mann–Whitney U test.</p><p>6 M, six months; BMI, body mass index; CPK, creatine- phosphor-kinase; CKMB, creatine phosphokinase-MB; HbA1C, glycohemoglobin; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; hsCRP, high sensitivity C reactive protein; IL-6, interleukin 6; WMSI, wall motion score index; TIMI, thrombolysis in myocardial infarction; LVMI, left ventricular mass index; LVEF, left ventricular ejection fraction; E/A ratio, the ratio of the peak velocities of early (E wave) and late (A wave) diastolic filling; DT, the deceleration time of the E wave; EDV, left ventricular end diastolic volume; ESV, left ventricular end systolic volume; Hb, hemoglobin; RDW, red blood cell distribution width; LAD, left anterior descending artery; RCA, right coronary artery; LCX, left circumflex artery; D2B, door to balloon; PCI, percutaneous coronary interventions; TIMI, thrombolysis in myocardial infarction.</p

The relationships between serum iron concentration and TIMI risk scores after primary angioplasty for AMI.

<p>The AMI patients were divided into four subgroups according to TIMI risk score for STEMI: Group 1 (TIMI risk score 1, n = 8); Group 2 (TIMI risk score 2, n = 15); Group 3 (TIMI risk score 3, n = 19); and Group 4 (TIMI risk score ≥4, n = 13). Trend analysis with Jonckheere-Terpstra test found that serum iron concentration significantly decreased as TIMI risk score rose (<i>P</i> = 0.002).</p

Lower serum iron concentration is associated with higher inflammatory markers and TIMI risk score after acute myocardial infarction.

<p>*<i>P</i><0.05, Mann–Whitney U test. TIMI, thrombolysis in myocardial infarction; IL-6, interleukin 6.</p