Evidence for Preferential Solvation in the Cyclohexane/<i>n</i>‑Butanol Binary Solvent System

We report on the rotational diffusion and vibrational population relaxation dynamics of the polycyclic aromatic hydrocarbon (PAH) perylene in a series of cyclohexane/<i>n</i>-butanol binary solvent systems. The molecular scale heterogeneity of this binary system is seen in both types of data. The rotational diffusion results show that in neat <i>n</i>-butanol and neat cyclohexane perylene reorients as an oblate rotor, but for all binary solvent systems examined this chromophore reorients as a prolate rotor. The perylene ring breathing mode is nearly degenerate with the <i>n</i>-butanol terminal methyl group rocking mode and vibrational population relaxation data for the perylene ring breathing mode reveal a substantial decrease in the relaxation time constant with the addition of small amounts of <i>n</i>-butanol to cyclohexane. This finding, in concert with the rotational diffusion data, indicates that perylene is solvated preferentially by <i>n</i>-butanol in cyclohexane/<i>n</i>-butanol binary solvent systems. The implication of this finding is that the cyclohexane/<i>n</i>-butanol binary solvent mixture is not homogeneous on nanometer length scales

Additional file 2: of The ratio of the seroprevalence to the egg-positive prevalence of Schistosoma japonicum in China: a meta-analysis

Sensitivity analyses for IHA to Kato-Katz by single-study-omitted. (TIF 447 kb

Additional file 5: of The ratio of the seroprevalence to the egg-positive prevalence of Schistosoma japonicum in China: a meta-analysis

Sensitivity analyses for ELISA to Kato-Katz by single-paper-omitted. (TIF 214 kb

Additional file 3: of The ratio of the seroprevalence to the egg-positive prevalence of Schistosoma japonicum in China: a meta-analysis

Sensitivity analyses for ELISA to Kato-Katz by single-study-omitted. (TIF 356 kb

Additional file 4: of The ratio of the seroprevalence to the egg-positive prevalence of Schistosoma japonicum in China: a meta-analysis

Sensitivity analyses for IHA to Kato-Katz by single-paper-omitted. (TIF 247 kb

Additional file 1: of The ratio of the seroprevalence to the egg-positive prevalence of Schistosoma japonicum in China: a meta-analysis

PROSPERO (CRD42017067941): A meta-analysis of the ratio of seroprevalence to egg-positive prevalence of Schistosoma japonicum in China. (PDF 117 kb

Image_2_Lack of Association of rs1192415 in TGFBR3-CDC7 With Visual Field Progression: A Cohort Study in Chinese Open Angle Glaucoma Patients.JPEG

To investigate the association of known candidate genes with the visual field (VF) progression of primary open angle glaucoma (POAG) in a Han Chinese population. We included 440 POAG patients in this study. Fourteen previously reported single nucleotide polymorphisms (SNPs) at five different gene regions (TGFBR3-CDC7, TMCO1, CDKN2B-AS1, ATOH7, and SIX1/SIX6) were genotyped. Age at diagnosis, gender, intraocular pressure (IOP), mean defect (MD) of VF, vertical cup disk ratio (VCDR), best corrected visual acuity (BCVA), central corneal thickness (CCT), and axial length (AL) were recorded at baseline. Patients were followed up for 5 years to evaluate VF progression over time. Clinical information and allele frequencies of 14 SNPs were compared between patients who progressed and who did not within 5 years by multivariate logistic regression. Survival analysis was performed to evaluate the contribution of the associated SNP by cox regression. Greater MD (P < 0.0001), increased VCDR (P = 0.0001), higher IOP (P = 0.0003), worse BCVA (P = 0.002), and older age (P = 0.030) at the baseline were associated with VF progression. Both multivariate logistic regression and cox regression survival analysis showed none of the 14 SNPs statistically associated with VF progression adjusted with age at diagnosis, gender, baseline MD, follow-up IOP, CCT, and AL. There were lack of association of SNPs at TGFBR3-CDC7, TMCO1, ATOH7, CDKN2B-AS1, SIX1/SIX6 loci with VF progression in POAG patients in Han Chinese. Further studies are needed to evaluate the association of genetic variants with VF progression.</p

MOESM1 of An effective snakebite first aid training method for medics in the Chinese troops: a RCT

Additional file 1. Part 1. Scoring table for snakebite first aid. Part 2. Snakebite scenarios. Part 3. A socio-demographic information questionnaire. Part 4. Acceptance questionnaire of the SOP and checklist

Table_2_Lack of Association of rs1192415 in TGFBR3-CDC7 With Visual Field Progression: A Cohort Study in Chinese Open Angle Glaucoma Patients.DOC

To investigate the association of known candidate genes with the visual field (VF) progression of primary open angle glaucoma (POAG) in a Han Chinese population. We included 440 POAG patients in this study. Fourteen previously reported single nucleotide polymorphisms (SNPs) at five different gene regions (TGFBR3-CDC7, TMCO1, CDKN2B-AS1, ATOH7, and SIX1/SIX6) were genotyped. Age at diagnosis, gender, intraocular pressure (IOP), mean defect (MD) of VF, vertical cup disk ratio (VCDR), best corrected visual acuity (BCVA), central corneal thickness (CCT), and axial length (AL) were recorded at baseline. Patients were followed up for 5 years to evaluate VF progression over time. Clinical information and allele frequencies of 14 SNPs were compared between patients who progressed and who did not within 5 years by multivariate logistic regression. Survival analysis was performed to evaluate the contribution of the associated SNP by cox regression. Greater MD (P < 0.0001), increased VCDR (P = 0.0001), higher IOP (P = 0.0003), worse BCVA (P = 0.002), and older age (P = 0.030) at the baseline were associated with VF progression. Both multivariate logistic regression and cox regression survival analysis showed none of the 14 SNPs statistically associated with VF progression adjusted with age at diagnosis, gender, baseline MD, follow-up IOP, CCT, and AL. There were lack of association of SNPs at TGFBR3-CDC7, TMCO1, ATOH7, CDKN2B-AS1, SIX1/SIX6 loci with VF progression in POAG patients in Han Chinese. Further studies are needed to evaluate the association of genetic variants with VF progression.</p

data_Axial myopia and VF progression

We collected the original data at Eye and Ear, Nose and Throat Hospital of Fudan University, Shanghai, China. eye: "1"=left, "2"=right; gender: "1"=male, "2"=female; SE = spherical equivalent; BCVA(logMAR) = logarithm of the minimum angle of resolution of best-corrected visual acuity; CCT = central corneal thickness; VCDR = vertical cup-to-disk ratio; MD = mean defect; IOP = intraocular pressure; AXL = axial length; GAXL = grouping by axial length;diagnosis: "1" = high tension glaucoma, "2" = normal tension glaucoma; GSE = grouping by spherical equivalent; FastPro(0.22) = fast/slow progression at the cutoff threshold 0.22; FastPro(0.30) = fast/slow progression at the cutoff threshold 0.30