Additional file 1 of Association between early ondansetron administration and in-hospital mortality in critically ill patients: analysis of the MIMIC-IV database

Additional file 1: Fig. S1. Standardized mean differences (SMDs) of variables in unmatched, propensity score matching (PSM) and inverse probability of treatment weighting (IPTW) models. cc: complications; vent 1st day: mechanical ventilation within the first 24 h after ICU admission; vaso 1st day: vasopressors within the first 24 h after ICU admission; sofa 1st day: sequential organ failure assessment score within the first 24 h after ICU admission; sapsii 1st day: simplified acute physiology score ii score within the first 24 h after ICU admission; Unmatched: unmatched data(red line); Matched: propensity score matching (PSM) (green line); Weighted: inverse probability of treatment weighting (IPTW) (blue line)

Additional file 2 of Association between early ondansetron administration and in-hospital mortality in critically ill patients: analysis of the MIMIC-IV database

Additional file 2: Table S1. Percentage of missing data in the variables in the interest

Additional file 1: of A General One-Pot Approach to Synthesize Binary and Ternary Metal Sulfide Nanocrystals

Figure S1. The XPS signals of (a) Full-scan and (b) Cu 2p for CdS:Cu NCs with different Cu doping levels. (DOCX 162 kb

Association between postoperative ibuprofen exposure and acute kidney injury after pediatric cardiac surgery

Acute kidney injury (AKI) is a common complication after pediatric cardiac surgery and is associated with worse outcomes. Ibuprofen is widely used in the perioperative period and can affect kidney function in children. However, the association between ibuprofen exposure and AKI after pediatric cardiac surgery has not been determined yet. In this retrospective cohort study, children undergoing cardiac surgery with cardiopulmonary bypass were studied. Exposure was defined as given ibuprofen in the first 7 days after surgery. Postoperative AKI was diagnosed using the KDIGO criteria. A multivariable Cox regression model was used to assess the association between ibuprofen exposure and postoperative AKI by taking ibuprofen as a time-varying covariate. Among 1,112 included children, 198 of them (17.8%) experienced AKI. In total, 396 children (35.6%) were exposed to ibuprofen. AKI occurred less frequently among children who were administered ibuprofen than among those who were not (46 of 396 [11.6%] vs. 152 of 716 [21.2%], p p = 0.932). This insignificant association was consistent across the sensitivity and subgroup analyses. Postoperative ibuprofen exposure in pediatric patients undergoing cardiac surgery was not associated with an increased risk of AKI.</p

Additional file 1 of Home confinement’s impact on myopia control by using orthokeratology in school-aged children

Additional file 1

Additional file 1: of Complement activation contributes to perioperative neurocognitive disorders in mice

Representative images of C3/NeuN double immunostaining show no detectable C3 in hippocampal neurons on day 1. (PDF 3770 kb

Additional file 3 of Home confinement’s impact on myopia control by using orthokeratology in school-aged children

Additional file 3

Additional file 2 of Home confinement’s impact on myopia control by using orthokeratology in school-aged children

Additional file 2

Response of Bacteria Community to Long-Term Inorganic Nitrogen Application in Mulberry Field Soil

<div><p>The bacterial community and diversity in mulberry field soils with different application ages of inorganic nitrogen fertilizer (4Y, 4-year-old; 17Y, 17-year-old; 32Y, 32-year- old) were investigated using next-generation sequencing. The results demonstrated that the application ages of nitrogen fertilizer significantly altered soil bacterial community and diversity. Soil bacterial Shannon diversity index and Chao 1 index decreased with the consecutive application of nitrogen fertilizer, and the 4Y soil exhibited the highest bacterial relative abundance and diversity. Of 45 bacterial genera (relative abundance ratio of genera greater than 0.3%), 18 were significantly affected by the plant age, and seven belong to <i>Acidobacteria</i>. The relative abundances of <i>Acidobacteria</i> Gp 1, Gp4 and Gp6 in the 4Y soil were significantly lower than that of in the 17Y and 32Y soils. However, the relative abundance of <i>Pseudononas</i> sp. in the 4Y soil was significantly higher than that of in the 17Y and 32Y soils. Most microbial parameters were significantly affected by soil pH and organic matter content which were significantly changed by long-term application of inorganic nitrogen fertilizer.</p></div

Comparisons (T-test) for genus abundance between the nitrogen application of 4-year-old (4Y), 17-year-old (17Y), and 32-year-old (32Y) mulberry field soils.

<p>Comparisons (T-test) for genus abundance between the nitrogen application of 4-year-old (4Y), 17-year-old (17Y), and 32-year-old (32Y) mulberry field soils.</p