Employee Empowerment: A Strategy towards Workplace Commitment

Employee empowerment starts with the concept of strategic fit between people, tasks, technology, information processes, rewards and organization structure for which all must be in alignment before the organization can work efficiently. Employees with strong organizational commitment are emotionally attached to the organization and have strong desire to contribute significantly towards organizational success. This leads to increased competitiveness, accountability, risk taking, highly innovativeness, low wastage, and the desire to improve overall job performance. Moreover, increased individual commitment and commitment to work groups or teams improves team performance, interpersonal interaction, and enhances individual performance and degree of satisfaction. Empowerment thus inspires change and increases the level of workplace commitment which increases the degree of individual employee commitment and helping for achievement of organizational goal. Keyword: employee empowerment, strategy, workplace commitment, organizational commitment, individual commitmen

Organizational Effort towards Performance Management System: A Key to Success

The basic purpose of performance management system is to create the alignment in between the organizational objectives and its subsystems to achieve the organizational objectives. Developing and managing performance management system is not an easy task. There should be consensus among employees when goals are developed.  The effective implementation of performance management system is the key to success for organizations looking for achievement of the organizational goals. The main goal of performance management is to ensure that the organization as a system and its subsystems work together in an integrated fashion for accomplishing optimum results or outcomes. This article begins with a review of definitions and descriptions of performance management system and demonstrates its impact on individual employee performance and motivation towards organizational effectiveness. Keywords: organizational effort, performance appraisal, performance management system, balance scorecard, employees’ performance

Women Entrepreneurship and Connective Leadership: Achieving Success

Successful running of a business firm will require a balance between two different and often contradictory approaches: management and leadership. Rapid changes in both internal as well as external environment with respect to technology, govt. policies, customer demands, workers' expectations, etc. will require excellent entrepreneurial leadership skills. The women entrepreneurs should follow the connective leadership approach, which includes power direct achieving style, social instrumental style, and relational achieving style depending upon the situational demands. The women entrepreneurs in 21st century were very successful because of giving much more attention on management of intellectual capital, creation of self- organizing networks, proper counseling & guidance, clearly defined organizational goals, organizational design, transparency & collaboration, and consensus building & collaboration. Keywords: entrepreneurship, connective leadership, organizational design, consensus building and collaboration

Work–life balance, retention of professionals and psychological empowerment : an empirical validation

Purpose – This study aims to explore the relationship between work–life balance and employee retention by examining the mediating role of psychological empowerment among software firms based in India. Design/methodology/approach – The study collected 283 responses by using a structured questionnaire and interview method. Structural equation modeling (SEM) was used to validate the hypothesized research model for examining the consistency and sturdiness of the study variables by applying AMOS 20. Findings – The result reveals that psychological empowerment partially mediates the relationship between work–life balance and the retention of professionals. This indicates that a high degree of psychological empowerment strengthens the relations between work–life balance and the retention of professionals. Research limitations/implications – The research outlined a best-fit model of psychological empowerment as a partial mediator among work–life balance and the retention of professionals. The study presents a set of sensible and practical aspects where work–life balance and retention of professionals can aid in developing and generating commitment to the organization which could offer new insights for software professionals, managers and practitioners. Originality/value – This study emphasized that psychological empowerment helps in enhancing dedication, loyalty, integrity, allegiance and trustworthiness among employees, thus playing a role between work–life balance and the retention of professionals.info:eu-repo/semantics/publishedVersio

NationalConference on Construction, sustainable Infrastructure and Valorization of waste-2023

Gandhi Institute of Excellent Technocrats, Ghangapatna, BBSR is organizing a conference, “National Conference on Construction, sustainable Infrastructure and Valorization of waste-2023” on 6th& 7thOctober 2023, at GIET, Ghangapatna, BBSR. The conference provides a platform for deliberations on developing solutions that mitigate the impact of infrastructure on ecology and environment. Research and case studies on challenges, underlying opportunities and innovative ideas for the development of sustainable infrastructure will be presented and discussed.https://www.interscience.in/conf_proc_volumes/1089/thumbnail.jp

National Conference on ‘Renewable Energy, Smart Grid and Telecommunication-2023

Theme of the Conference: “The challenges and opportunities of integrating renewable energy into the grid” The National Conference on Renewable Energy, Smart Grid, and Telecommunication - 2023 is a platform for industry experts, researchers, and policymakers to come together and explore the latest advancements and challenges in the fields of renewable energy, smart grids, and telecommunication. Conference Highlights: In-depth discussions on renewable energy technologies and innovations. Smart grid integration for a sustainable future. The role of telecommunication in advancing renewable energy solutions. Networking opportunities with industry leaders and experts. Presentation of cutting-edge research papers and case studies. Conference topics: Renewable Energy Technologies and Innovations Smart Grid Development and Implementation Telecommunication for Energy Systems Energy Storage and Grid Balancing Policy, Regulation, and Market Dynamics Environmental and Social Impacts of Renewable Energy Energy Transition and Future Outlook Integration of renewable energy into the grid Microgrids and decentralized energy systems Grid cybersecurity and data analytics IoT and sensor technologies for energy monitoring Data management and analytics in energy sector Battery storage technologies and applicationshttps://www.interscience.in/conf_proc_volumes/1087/thumbnail.jp

National Conference on COMPUTING 4.0 EMPOWERING THE NEXT GENERATION OF TECHNOLOGY (Era of Computing 4.0 and its impact on technology and intelligent systems)

As we enter the era of Computing 4.0, the landscape of technology and intelligent systems is rapidly evolving, with groundbreaking advancements in artificial intelligence, machine learning, data science, and beyond. The theme of this conference revolves around exploring and shaping the future of these intelligent systems that will revolutionize industries and transform the way we live, work, and interact with technology. Conference Topics Quantum Computing and Quantum Information Edge Computing and Fog Computing Artificial Intelligence and Machine Learning in Computing 4.0 Internet of Things (IOT) and Smart Cities Block chain and Distributed Ledger Technologies Cybersecurity and Privacy in the Computing 4.0 Era High-Performance Computing and Parallel Processing Augmented Reality (AR) and Virtual Reality (VR) Applications Cognitive Computing and Natural Language Processing Neuromorphic Computing and Brain-Inspired Architectures Autonomous Systems and Robotics Big Data Analytics and Data Science in Computing 4.0https://www.interscience.in/conf_proc_volumes/1088/thumbnail.jp

Palmitate induces integrated stress response and lipoapoptosis in trophoblasts

Maternal obesity increases the risk of childhood obesity and programs the offspring to develop metabolic syndrome later in their life. Palmitate is the predominant saturated free fatty acid (FFA) that is transported across the placenta to the fetus. We have recently shown that saturated FFA in the maternal circulation as a result of increased adipose tissue lipolysis in third trimester of pregnancy induces trophoblast lipoapoptosis. Here, we hypothesized that palmitate induces integrated stress response by activating mitogen-activated protein kinases (MAPKs), endoplasmic reticulum (ER) stress and granular stress and lipoapoptosis in trophoblasts. Choriocarcinoma-derived third-trimester placental trophoblast-like cells (JEG-3 and JAR) referred as trophoblasts were exposed to various concentrations of palmitate (PA). Apoptosis was assessed by nuclear morphological changes and caspase 3/7 activity. Immunoblot and immunofluorescence analysis was performed to measure the activation of MAPKs, ER stress and granular stress response pathways. Trophoblasts exposed to pathophysiological concentrations of PA showed a concentration-dependent increase in trophoblast lipoapoptosis. PA induces a caspase-dependent trophoblast lipoapoptosis. Further, PA induces MAPK activation (JNK and ERK) via phosphorylation, and activation of ER stress as evidenced by an increased phosphorylation eIF2α & IRE1α. PA also induces the activation of stress granules formation. Two pro-apoptotic transcriptional mediators of PA-induced trophoblast lipoapoptosis, CHOP and FoxO3 have increased nuclear translocation. Mechanistically, PA-induced JNK is critical for trophoblast lipoapoptosis. However, PA-induced activation of ERK and stress granule formation were shown to be cell survival signals to combat subcellular stress due to PA exposure. In conclusion, PA induces the activation of integrated stress responses, among which small molecule inhibition of JNK demonstrated that activation of JNK is critical for PA-induced trophoblast lipoapoptosis and small molecule activation of stress granule formation significantly prevents PA-induced trophoblast lipoapoptosis

P38 and JNK Mitogen-Activated Protein Kinases Interact With Chikungunya Virus Non-structural Protein-2 and Regulate TNF Induction During Viral Infection in Macrophages

Chikungunya virus (CHIKV), a mosquito-borne Alphavirus, is endemic in different parts of the globe. The host macrophages are identified as the major cellular reservoirs of CHIKV during infection and this virus triggers robust TNF production in the host macrophages, which might be a key mediator of virus induced inflammation. However, the molecular mechanism underneath TNF induction is not understood yet. Accordingly, the Raw264.7 cells, a mouse macrophage cell line, were infected with CHIKV to address the above-mentioned question. It was observed that CHIKV induces both p38 and JNK phosphorylation in macrophages in a time-dependent manner and p-p38 inhibitor, SB203580 is effective in reducing infection even at lower concentration as compared to the p-JNK inhibitor, SP600125. However, inhibition of p-p38 and p-JNK decreased CHIKV induced TNF production in the host macrophages. Moreover, CHIKV induced macrophage derived TNF was found to facilitate TCR driven T cell activation. Additionally, it was noticed that the expressions of key transcription factors involved mainly in antiviral responses (p-IRF3) and TNF production (p-c-jun) were induced significantly in the CHIKV infected macrophages as compared to the corresponding mock cells. Further, it was demonstrated that CHIKV mediated TNF production in the macrophages is dependent on p38 and JNK MAPK pathways linking p-c-jun transcription factor. Interestingly, it was found that CHIKV nsP2 interacts with both p-p38 and p-JNK MAPKs in the macrophages. This observation was supported by the in silico protein-protein docking analysis which illustrates the specific amino acids responsible for the nsP2-MAPKs interactions. A strong polar interaction was predicted between Thr-180 (within the phosphorylation lip) of p38 and Gln-273 of nsP2, whereas, no such polar interaction was predicted for the phosphorylation lip of JNK which indicates the differential roles of p-p38 and p-JNK during CHIKV infection in the host macrophages. In summary, for the first time it has been shown that CHIKV triggers robust TNF production in the host macrophages via both p-p38 and p-JNK/p-c-jun pathways and the interaction of viral protein, nsP2 with these MAPKs during infection. Hence, this information might shed light in rationale-based drug designing strategies toward a possible control measure of CHIKV infection in future

Diabetes mortality and trends before 25 years of age: an analysis of the Global Burden of Disease Study 2019

Background Diabetes, particularly type 1 diabetes, at younger ages can be a largely preventable cause of death with the correct health care and services. We aimed to evaluate diabetes mortality and trends at ages younger than 25 years globally using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Methods We used estimates of GBD 2019 to calculate international diabetes mortality at ages younger than 25 years in 1990 and 2019. Data sources for causes of death were obtained from vital registration systems, verbal autopsies, and other surveillance systems for 1990–2019. We estimated death rates for each location using the GBD Cause of Death Ensemble model. We analysed the association of age-standardised death rates per 100 000 population with the Socio-demographic Index (SDI) and a measure of universal health coverage (UHC) and described the variability within SDI quintiles. We present estimates with their 95% uncertainty intervals. Findings In 2019, 16 300 (95% uncertainty interval 14 200 to 18 900) global deaths due to diabetes (type 1 and 2 combined) occurred in people younger than 25 years and 73·7% (68·3 to 77·4) were classified as due to type 1 diabetes. The age-standardised death rate was 0·50 (0·44 to 0·58) per 100 000 population, and 15 900 (97·5%) of these deaths occurred in low to high-middle SDI countries. The rate was 0·13 (0·12 to 0·14) per 100 000 population in the high SDI quintile, 0·60 (0·51 to 0·70) per 100 000 population in the low-middle SDI quintile, and 0·71 (0·60 to 0·86) per 100 000 population in the low SDI quintile. Within SDI quintiles, we observed large variability in rates across countries, in part explained by the extent of UHC (r2=0·62). From 1990 to 2019, age-standardised death rates decreased globally by 17·0% (−28·4 to −2·9) for all diabetes, and by 21·0% (–33·0 to −5·9) when considering only type 1 diabetes. However, the low SDI quintile had the lowest decline for both all diabetes (−13·6% [–28·4 to 3·4]) and for type 1 diabetes (−13·6% [–29·3 to 8·9]). Interpretation Decreasing diabetes mortality at ages younger than 25 years remains an important challenge, especially in low and low-middle SDI countries. Inadequate diagnosis and treatment of diabetes is likely to be major contributor to these early deaths, highlighting the urgent need to provide better access to insulin and basic diabetes education and care. This mortality metric, derived from readily available and frequently updated GBD data, can help to monitor preventable diabetes-related deaths over time globally, aligned with the UN's Sustainable Development Targets, and serve as an indicator of the adequacy of basic diabetes care for type 1 and type 2 diabetes across nations.publishedVersio