14,935 research outputs found
Resolving the UK construction skills crisis : a critical perspective on the research and policy agenda
The ongoing skills crisis in the UK construction industry has constrained the productive capacity of the industry. Past research and skills policies have largely failed to develop an understanding of the realities of the skills crisis at the grassroots level. Solutions offered by researchers and policy makers have previously had little demonstrable impact in addressing skills concerns. Much of these policies seems disconnected from the realities experienced by employers and by those working in the industry. A critical perspective on resolving the skills crisis is offered. A set of mutually reinforcing research and policy initiatives are proposed, including the need for researchers and policy makers to move away from the conventionally national approach in addressing the skills problem and to engage in genuine, joined-up thinking that meets the needs of local regions. Furthermore, employers and employees are called to be reflective practitioners in their participation of the skills development agenda. Adopting these recommendations could overcome many shortcomings in research and policy that have hitherto done little to combat the construction skills crisis.Skills shortages, critical perspective, bottom-up approach, labour market, research,
Scaling laws for molecular communication
In this paper, we investigate information-theoretic scaling laws, independent
from communication strategies, for point-to-point molecular communication,
where it sends/receives information-encoded molecules between nanomachines.
Since the Shannon capacity for this is still an open problem, we first derive
an asymptotic order in a single coordinate, i.e., i) scaling time with constant
number of molecules and ii) scaling molecules with constant time . For a
single coordinate case, we show that the asymptotic scaling is logarithmic in
either coordinate, i.e., and , respectively.
We also study asymptotic behavior of scaling in both time and molecules and
show that, if molecules and time are proportional to each other, then the
asymptotic scaling is linear, i.e., .Comment: Accepted for publication in the 2014 IEEE International Symposium on
Information Theor
Estimation of fractal dimension for a class of Non-Gaussian stationary processes and fields
We present the asymptotic distribution theory for a class of increment-based
estimators of the fractal dimension of a random field of the form g{X(t)},
where g:R\to R is an unknown smooth function and X(t) is a real-valued
stationary Gaussian field on R^d, d=1 or 2, whose covariance function obeys a
power law at the origin. The relevant theoretical framework here is ``fixed
domain'' (or ``infill'') asymptotics. Surprisingly, the limit theory in this
non-Gaussian case is somewhat richer than in the Gaussian case (the latter is
recovered when g is affine), in part because estimators of the type considered
may have an asymptotic variance which is random in the limit. Broadly, when g
is smooth and nonaffine, three types of limit distributions can arise, types
(i), (ii) and (iii), say. Each type can be represented as a random integral.
More specifically, type (i) can be represented as the integral of a certain
random function with respect to Lebesgue measure; type (ii) can be represented
as the integral of a second random functio
Scott Ranks of Classifications of the Admissibility Equivalence Relation
Let be a recursive language. Let be the set of
-structures with domain . Let be a function with the property that
for all , if and only if
. Then there is some
so that
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The diagnosis and treatment of elderly patients with acute exacerbation of chronic obstructive pulmonary disease and chronic bronchitis.
The syndrome of chronic obstructive pulmonary disease (COPD) consists of chronic bronchitis (CB), bronchiectasis, emphysema, and reversible airway disease that combine uniquely in an individual patient. Older patients are at risk for COPD and its components--emphysema, CB, and bronchiectasis. Bacterial and viral infections play a role in acute exacerbations of COPD (AECOPD) and in acute exacerbations of CB (AECB) without features of COPD. Older patients are at risk for resistant bacterial organisms during their episodes of AECOPD and AECB. Organisms include the more-common bacteria implicated in AECOPD/AECB such as Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae. Less-common nonenteric, gram-negative organisms including Pseudomonas aeruginosa, gram-positive organisms including Staphylococcus aureus, and strains of nontuberculosis Mycobacteria are more often seen in AECOPD/AECB episodes involving elderly patients with frequent episodes of CB or those with bronchiectasis. Risk-stratified antibiotic treatment guidelines appear useful for purulent episodes of AECOPD and episodes of AECB. These guidelines have not been prospectively validated for the general population and especially not for the elderly population. Using a risk-stratification approach for elderly patients, first-line antibiotics (e.g., amoxicillin, ampicillin, pivampicillin, trimethoprim/sulfamethoxazole, and doxycycline), with a more-limited spectrum of antibacterial coverage, are used in patients who are likely to have a low probability of resistant organisms during AECOPD/AECB. Second-line antibiotics (e.g., amoxicillin/clavulanic acid, second- or third-generation cephalosporins, and respiratory fluoroquinolones) with a broader spectrum of coverage are reserved for patients with significant risk factors for resistant organisms and those who have failed initial antibiotic treatment
Detection Algorithms for Molecular MIMO
In this paper, we propose a novel design for molecular communication in which
both the transmitter and the receiver have, in a 3-dimensional environment,
multiple bulges (in RF communication this corresponds to antenna). The proposed
system consists of a fluid medium, information molecules, a transmitter, and a
receiver. We simulate the system with a one-shot signal to obtain the channel's
finite impulse response. We then incorporate this result within our
mathematical analysis to determine interference. Molecular communication has a
great need for low complexity, hence, the receiver may have incomplete
information regarding the system and the channel state. Thus, for the cases of
limited information set at the receiver, we propose three detection algorithms,
namely adaptive thresholding, practical zero forcing, and Genie-aided zero
forcing.Comment: 6 pages, 6 figures, 2015 IEEE ICC accepte
Telescoper: de novo assembly of highly repetitive regions.
MotivationWith advances in sequencing technology, it has become faster and cheaper to obtain short-read data from which to assemble genomes. Although there has been considerable progress in the field of genome assembly, producing high-quality de novo assemblies from short-reads remains challenging, primarily because of the complex repeat structures found in the genomes of most higher organisms. The telomeric regions of many genomes are particularly difficult to assemble, though much could be gained from the study of these regions, as their evolution has not been fully characterized and they have been linked to aging.ResultsIn this article, we tackle the problem of assembling highly repetitive regions by developing a novel algorithm that iteratively extends long paths through a series of read-overlap graphs and evaluates them based on a statistical framework. Our algorithm, Telescoper, uses short- and long-insert libraries in an integrated way throughout the assembly process. Results on real and simulated data demonstrate that our approach can effectively resolve much of the complex repeat structures found in the telomeres of yeast genomes, especially when longer long-insert libraries are used.AvailabilityTelescoper is publicly available for download at sourceforge.net/p/[email protected] informationSupplementary data are available at Bioinformatics online
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