12 research outputs found

    Young Children’s Behaviors During Favorite-Music Repertoire And Other-Music Repertoire

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    To gain understanding regarding early childhood music repertoire selection, the purpose of this qualitative case study was to examine young children’s music behaviors demonstrated in response to their favorite-music repertoire and other-music repertoire performed in informal early childhood music classes. My guiding research questions were (a) what was the favorite-music repertoire of young children, and (b) what did parents, Alli (an early childhood music teacher), Kat (an early childhood music teacher), and I notice about behaviors young children demonstrated during performances of their favorite-music repertoire and other-music repertoire during our informal music classes? I purposefully sampled three young children and asked their parents, my coteacher and another early childhood music teacher to participate as observers. I participated as a complete participant observer. My co-teacher and I facilitated 10 weeks of Music Play classes based on Gordon’s (2013) Music Learning Theory for Newborn and Young Children and Valerio, Reynolds, Taggart, Bolton, & Gordon’s (1998) Music Play. I gathered data from parent questionnaires, video-recorded Music Play classes, written observations and reflections, audio-recorded individual think-aloud interviews. I transcribed all data for subsequent analysis. I coded that data and created a taxonomic analysis to organize cultural domains. Three themes emerged. Young children repeatedly demonstrated specific patterns from their favorite-music repertoire. Young children demonstrated related behaviors during favorite music and other music. Young children demonstrated unrelated behaviors during favorite music and other music. I provide preliminary definitions and thick, rich descriptions of the behaviors young children demonstrated during favorite-music repertoire and other-music repertoire. Though I may not make generalizations based on this study, childhood music teachers may consider selecting young children’s favoritemusic repertoire to elicit young children’s rhythm pattern behaviors and tonal pattern behaviors that may provide the basis for increased young children’s rhythm pattern and tonal pattern vocabulary development and learning or to engage young children’s positive emotions during music classes

    Genetic mechanisms of critical illness in COVID-19.

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    Host-mediated lung inflammation is present1, and drives mortality2, in the critical illness caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with critical illness may identify mechanistic targets for therapeutic development3. Here we report the results of the GenOMICC (Genetics Of Mortality In Critical Care) genome-wide association study in 2,244 critically ill patients with COVID-19 from 208 UK intensive care units. We have identified and replicated the following new genome-wide significant associations: on chromosome 12q24.13 (rs10735079, P = 1.65 × 10-8) in a gene cluster that encodes antiviral restriction enzyme activators (OAS1, OAS2 and OAS3); on chromosome 19p13.2 (rs74956615, P = 2.3 × 10-8) near the gene that encodes tyrosine kinase 2 (TYK2); on chromosome 19p13.3 (rs2109069, P = 3.98 ×  10-12) within the gene that encodes dipeptidyl peptidase 9 (DPP9); and on chromosome 21q22.1 (rs2236757, P = 4.99 × 10-8) in the interferon receptor gene IFNAR2. We identified potential targets for repurposing of licensed medications: using Mendelian randomization, we found evidence that low expression of IFNAR2, or high expression of TYK2, are associated with life-threatening disease; and transcriptome-wide association in lung tissue revealed that high expression of the monocyte-macrophage chemotactic receptor CCR2 is associated with severe COVID-19. Our results identify robust genetic signals relating to key host antiviral defence mechanisms and mediators of inflammatory organ damage in COVID-19. Both mechanisms may be amenable to targeted treatment with existing drugs. However, large-scale randomized clinical trials will be essential before any change to clinical practice

    Emotions in sexual morality: Testing the separate elicitors of anger and disgust

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    Recent work suggests that negative moral judgements of sexual activities are informed by disgust and anger. A correlational study (N = 62) and an experiment (N = 176) examined the specific antecedents that elicit these distinct, though correlated, moral emotions. Participants in Study 1 rated their emotional reactions to, and judgements of, 10 sexual scenarios. Across scenarios, judgements of abnormality predicted disgust independent of anger, and judgements of harm/rights violation predicted anger independent of disgust. Study 2 replicated these results in an experimental design. Participants rated their emotions and judgements in response to behaviours that varied in degree of potential sexual morality violation (non-sexual, heterosexual, homosexual) and rights violation (no harm, indirect harm, direct harm). Judgement of rights violation mediated the effects of harm on anger. Judgements of abnormality, but not other antecedents proposed to elicit moral disgust, mediated the effects of sexual immorality on disgust. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract

    An Integrated Population Model From Constant Effort Bird-Ringing Data

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    Data from annual bird-ringing programs, in which catch effort is standardized, are routinely used to index abundance, productivity, and adult survival. Efficient models have been developed for each. Such monitoring schemes, based on ringing across a number of sites, are perhaps unique in providing this combination of demographic information and make the data particularly amenable to an integrated approach to population modeling. We develop a Bayesian approach and a deterministic population model uniting abundance, productivity, and survival. The method is applied to sedge warbler Acrocephalus schoenobaenus data from the British Trust for Ornithology‚Äôs Constant Effort Sites scheme. The possibility of ‚Äútransient‚ÄĚ birds needs to be incorporated within this analysis. We demonstrate how current methodology can efficiently be extended to use additional data from multiple within year recaptures when controlling for transience. Supplemental materials for this article are available online