An investigation into the food related traditions associated with the Christmas period in rural Ireland

The interdisciplinary nature of food studies lends itself to the study of food through many avenues, most notably in this research, through folklore and the oral history transcripts of the Schools’ Collection made by the Irish Folklore Commission in 1937–1938. Folklore can give us an insight into sometimes overlooked features of society and how people’s lives can be studied and highlighted through their relationship with food. The Christmas period was an extremely important time in Irish tradition, and food was a main aspect of that celebration. This paper, therefore, at first delves into the literature surrounding Christmas, folklore, and food; diet and social class; gender, and food in rural Ireland, before comparing it with the oral history transcripts of the National Folklore Collection’s online archive, to unearth a better understanding of the relation[1]ship and the role of food in the Christmas festival in Ireland’s recent pas

Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN-γ in a nitric oxide-dependent manner

Immunodeficiency in chronic granulomatous disease (CGD) is well characterized. Less understood are exaggerated sterile inflammation and autoimmunity associated with CGD. Impaired recognition and clearance of apoptotic cells resulting in their disintegration may contribute to CGD inflammation. We hypothesized that priming of macrophages (Ms) with IFN-γ would enhance impaired engulfment of apoptotic cells in CGD. Diverse M populations from CGD (gp91(phox)(-/-)) and wild-type mice, as well as human Ms differentiated from monocytes and promyelocytic leukemia PLB-985 cells (with and without mutation of the gp91(phox)), demonstrated enhanced engulfment of apoptotic cells in response to IFN-γ priming. Priming with IFN-γ was also associated with increased uptake of Ig-opsonized targets, latex beads, and fluid phase markers, and it was accompanied by activation of the Rho GTPase Rac. Enhanced Rac activation and phagocytosis following IFN-γ priming were dependent on NO production via inducible NO synthase and activation of protein kinase G. Notably, endogenous production of TNF-α in response to IFN-γ priming was critically required for inducible NO synthase upregulation, NO production, Rac activation, and enhanced phagocytosis. Treatment of CGD mice with IFN-γ also enhanced uptake of apoptotic cells by M in vivo via the signaling pathway. Importantly, during acute sterile peritonitis, IFN-γ treatment reduced excess accumulation of apoptotic neutrophils and enhanced phagocytosis by CGD Ms. These data support the hypothesis that in addition to correcting immunodeficiency in CGD, IFN-γ priming of Ms restores clearance of apoptotic cells and may thereby contribute to resolution of exaggerated CGD inflammation

Incentives for sustainability in the European Union: Analysis of institutional factors, governance issues, and tax policy

Sustainability and the debate over climate change have become hot topics in the literature and news. Global reactions to the mounting scientific evidence have evolved rapidly in recent years, as an increased sense of urgency has emerged. On September 27, 2013, the IPCC announced that there is a 95% probability that climate change has been caused by humans. This announcement, in conjunction with extreme weather events in recent years, has created even more urgency for policymakers to address climate change issues. Since the EU has been successful in decreasing its GHG emissions, its institutional factors, governance structure, and energy tax policies are examined. Institutional structures vary greatly between developed and developing countries, which may impact the “green-ness” of firms operating within those regions. Previous studies examine institutional factors in both developed and developing nations; however, the literature lacks sufficient research in the area of “green-specific” institutional factors. The “green-ness” of firms in developed versus developing countries is examined. The “greenness” of firms from EU-member nations are also compared to those based in both developed and developing countries. The Newsweek Green Index is tested for significance. Governance issues, specifically agency problems, are abundant in efforts to reduce global carbon emissions. Extensive research has been conducted related to firm-level governance; however, research is lacking in the area of agency issues inherent in global collaboration. Despite the EU’s multilateral governance structure, the EU was one of the few Kyoto members to reach its emissions reduction target for the period ended 2012; however, this could be offset by the inaction of developing countries. Since the EU “green” policies have focused on energy-related emissions, Eurostat’s emission data relative to developing countries (excluding deforestation) is tested. Tax policy is one of many methods which countries can use to reduce GHG emissions. Previous studies have focused on cap and trade as well as international tax competition; however, the literature lacks sufficient research on the effectiveness of the EU’s energy tax policies. This section examines the effectiveness of the 2003 EU Energy Taxation Directive in encouraging “green” activities. Eurostat’s “implicit tax rate on energy” is tested for significance. (Author abstract)Zilch, K.B. (2014). Incentives for sustainability in the European Union: Analysis of institutional factors, governance issues, and tax policy. Retrieved from http://academicarchive.snhu.eduDoctor of Philosophy (Ph.D.)International BusinessSchool of Busines

Behavioral Problems in Community-Dwelling People with Dementia

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73826/1/j.1547-5069.2000.00055.x.pd

Designing experimental conditions to use the Lotka-Volterra model to infer tumor cell line interaction types

The Lotka-Volterra model is widely used to model interactions between two species. Here, we generate synthetic data mimicking competitive, mutualistic and antagonistic interactions between two tumor cell lines, and then use the Lotka-Volterra model to infer the interaction type. Structural identifiability of the Lotka-Volterra model is confirmed, and practical identifiability is assessed for three experimental designs: (a) use of a single data set, with a mixture of both cell lines observed over time, (b) a sequential design where growth rates and carrying capacities are estimated using data from experiments in which each cell line is grown in isolation, and then interaction parameters are estimated from an experiment involving a mixture of both cell lines, and (c) a parallel experimental design where all model parameters are fitted to data from two mixtures simultaneously. In addition to assessing each design for practical identifiability, we investigate how the predictive power of the model-i.e., its ability to fit data for initial ratios other than those to which it was calibrated-is affected by the choice of experimental design. The parallel calibration procedure is found to be optimal and is further tested on in silico data generated from a spatially-resolved cellular automaton model, which accounts for oxygen consumption and allows for variation in the intensity level of the interaction between the two cell lines. We use this study to highlight the care that must be taken when interpreting parameter estimates for the spatially-averaged Lotka-Volterra model when it is calibrated against data produced by the spatially-resolved cellular automaton model, since baseline competition for space and resources in the CA model may contribute to a discrepancy between the type of interaction used to generate the CA data and the type of interaction inferred by the LV model.Comment: 25 pages, 18 figure

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy

Assessing undergraduate nursing students\u27 attitude toward the dying using an ACE-S case study in simulation

A mixed-methods, multimodal approach was used to assess an undergraduate nursing students\u27 attitude towards the dying using a specifically designed lecture developed using the End-of-Life Nursing Education Consortium (ELNEC) competencies and an NLN ACE-s unfolding case study in simulation