3 research outputs found
Robust and Durable Superhydrophobic Cotton Fabrics for Oil/Water Separation
By
introducing the incorporation of polyaniline and fluorinated
alkyl silane to the cotton fabric via a facile vapor phase deposition
process, the fabric surface possessed superhydrophobicity with the
water contact angle of 156° and superoleophilicity with the oil
contact angle of 0°. The as-prepared fabric can be applied as
effective materials for the separation of water and oil mixture with
separation efficiency as high as 97.8%. Compared with other materials
for oil/water separation, the reported process was simple, time-saving,
and repeatable for at least 30 times. Moreover, the obtained fabric
kept stable superhydrophobicity and high separation efficiency under
extreme environment conditions of high temperature, high humidity,
strong acidic or alkaline solutions, and mechanical forces. Therefore,
this reported fabric has the advantages of scalable fabrication, high
separation efficiency, stable recyclability, and excellent durability,
exhibiting the strong potential for industrial production
Robust and Durable Superhydrophobic Cotton Fabrics for Oil/Water Separation
By
introducing the incorporation of polyaniline and fluorinated
alkyl silane to the cotton fabric via a facile vapor phase deposition
process, the fabric surface possessed superhydrophobicity with the
water contact angle of 156° and superoleophilicity with the oil
contact angle of 0°. The as-prepared fabric can be applied as
effective materials for the separation of water and oil mixture with
separation efficiency as high as 97.8%. Compared with other materials
for oil/water separation, the reported process was simple, time-saving,
and repeatable for at least 30 times. Moreover, the obtained fabric
kept stable superhydrophobicity and high separation efficiency under
extreme environment conditions of high temperature, high humidity,
strong acidic or alkaline solutions, and mechanical forces. Therefore,
this reported fabric has the advantages of scalable fabrication, high
separation efficiency, stable recyclability, and excellent durability,
exhibiting the strong potential for industrial production
Polydopamine and peptide decorated doxorubicin-loaded mesoporous silica nanoparticles as a targeted drug delivery system for bladder cancer therapy
<p>We reported a simple polydopamine (PDA)-based surface modification method to prepare novel targeted doxorubicin-loaded mesoporous silica nanoparticles and peptide CSNRDARRC conjugation (DOX-loaded MSNs@PDA-PEP) for enhancing the therapeutic effects on bladder cancer. Drug-loaded NPs were characterized in terms of size, size distribution, zeta potential, transmission electron microscopy (TEM), Brunauer–Emmett–Teller (BET) surface area and drug loading content. <i>In vitro</i> drug release indicated that DOX-loaded MSNs@PDA and MSNs@PDA-PEP had similar release kinetic profiles of DOX. The PDA coating well controlled DOX release and was highly sensitive to pH value. Confocal laser scanning microscopy (CLSM) showed that drug-loaded MSNs could be internalized by human bladder cancer cell line HT-1376, and DOX-loaded MSNs@PDA-PEP had the highest cellular uptake efficiency due to ligand–receptor recognition. The antitumor effects of DOX-loaded nanoparticles were evaluated by the MTT assay <i>in vitro</i> and by a xenograft tumor model <i>in vivo</i>, demonstrating that targeted nanocarriers DOX-loaded MSNs@PDA-PEP were significantly superior to free DOX and DOX-loaded MSNs@PDA. The novel DOX-loaded MSNs@PDA-PEP, which specifically recognized HT-1376 cells, can be used as a potential targeted drug delivery system for bladder cancer therapy.</p