Renal function trajectories.

<p>Renal function trajectories.</p

Change in kidney function and the risk of death.

<p>Model 1 adjusted for age, race, gender, diabetes mellitus, hypertension, cardiovascular disease, hyperlipidemia, peripheral artery disease, cerebrovascular disease, chronic lung disease, hepatitis C, HIV, dementia and eGFR at time of cohort entry (T0). Reference group is patients with stable kidney function (eGFR slope).</p

Flow chart for cohort selection.

<p>Flow chart for cohort selection.</p

Association between serum phosphorus and dementia subtypes.

<p>Association between serum phosphorus and dementia subtypes.</p

Renal function trajectory phenotypes.

<p>Renal function trajectory phenotypes.</p

Demographic and clinical characteristics of those with improved, stable, and declining eGFR slope.

<p>Demographic and clinical characteristics of those with improved, stable, and declining eGFR slope.</p

Risk of death of trajectory phenotypes.

<p>HIFNT = High Intercept and Fast Negative Trajectory includes trajectory F. HIPT = High Intercept Positive Trajectory and includes trajectory A and B; IIMNT = Intermediate Intercept Mild Negative Trajectory and includes trajectory C, and D; LIFNT = Low Intercept Fast Negative Trajectory and includes trajectory E and G; Model adjusted for age, race, gender, for age, race, gender, diabetes mellitus, hypertension, cardiovascular disease, hyperlipidemia, peripheral artery disease, cerebrovascular disease, chronic lung disease, hepatitis C, HIV, dementia, and eGFR at time of cohort entry (T0). Reference group is patients with stable kidney function before T0.</p

Demographic and clinical characteristics according to renal function trajectory.

<p>Demographic and clinical characteristics according to renal function trajectory.</p

Spline analyses for the relationship between serum phosphorus and risk of incident dementia with serum phosphorus probability distribution histogram represented in gray bars in the background.

<p>Fig 2a: Overall cohort. Fig 2b: Analysis was restricted to cohort participants with serum phosphorus level >2.5 mg/dl. Fig 2c: Analysis was restricted to cohort participants with serum phosphorus level >4.5 mg/dl.</p

Relationship between elevated serum phosphorus (quintile 5) and risk of dementia subtype by age group (≤60 and >60).

<p>Relationship between elevated serum phosphorus (quintile 5) and risk of dementia subtype by age group (≤60 and >60).</p