Diagnostic value of circulating miR-155 for breast cancer: a meta-analysis

BackgroundsThe value of circulating microRNA (miR)-155 for breast cancer (BC) diagnosis may differ in different studies. Therefore, we conducted this systematic review and meta-analysis to evaluate the potential application of circulating miR-155 in the diagnosis of BC.MethodsArticles published before December 2023 and in English were searched in these databases: PubMed, Web of Science, Medline, EMBASE and Google Scholar. A summary of sensitivity, specificity, positive likelihood ratios (PLR), negative likelihood ratios (NLR), and diagnostic odds ratio (DOR) were calculated from the true positive (TP), true negative (TN), false positive (FP) and false negative (FN) of each study. Additionally, the summary receive-operating characteristics (SROC) curve was constructed to summarize the TP and FP rates.ResultsThe pooled parameters calculated were as follows: sensitivity, 0.93 (95% CI: 0.83-0.97); specificity, 0.85 (95% CI: 0.74-0.92); PLR, 6.4 (95% CI: 3.4-11.9); NLR, 0.09 (95% CI: 0.04-0.20); and DOR, 74 (95% CI: 22-247). The analysis showed a significant heterogeneity (sensitivity, I2 = 95.19%, p < 0.001; specificity, I2 = 95.29%, p < 0.001; DOR, I2 = 92.9%, p < 0.001). The SROC curve was with an area under curve (AUC) of 0.95 (95% CI: 0.93-0.97).ConclusionCirculating miR-155 has a potential in the diagnosis of BC

Enhanced NH 3 gas-sensing performance of silica modified CeO 2 nanostructure based sensors

The silica modified CeO2 gas sensing nanomaterials are synthesized using a sol-hydrothermal route. The 8%silica-CeO2 has larger specific surface areas of 83.75 m2/g and smaller crystalline size of 11.5 nm than pure CeO2, respectively. Compared to pure CeO2, the 8%silica-CeO2 based gas sensor exhibits significant enhancement NH3 gas-sensing performance. At room temperature, it shows much better gas response of 3244% to 80 ppm of NH3 gas and lower detection limit (0.5 ppm) towards NH3 gas. It is also found that the gas response of the NH3 gas sensors increases linearly with the increase of NH3 gas concentration. Moreover, the NH3 gas sensor have good reversibility, stability and selectivity. The reason of enhanced NH3 gas-sensing performance is not only because of the increased specific surface areas, but also due to the electrolytic conductivity of NH4+ and OH− on the surface

Highly sensitive NH 3 gas sensor based on the porous Ce 0.94 Zr 0.06 O 2 nano-sheets with ppb level detection limit

Porous Ce0.94Zr0.06O2 nano-sheets sensing material was synthesized using a facile sol-hydrothermal process. The average thickness of the Ce0.94Zr0.06O2 nano-sheets was about 8 nm, and the nano-sheets were found to have a mesoporous structure with an average pore size around 2.1 nm. The mesoporous structure of Ce0.94Zr0.06O2 nano-sheets resulted in larger specific surface areas of 185.4 m2/g and more pore volumes of 0.51 cm3/g than those of CeO2, which was beneficial to the absorption of target gas. Due to the special mesoporous structures in the nano-sheets and the plenty of hydroxyl groups on the surface, the NH3 sensors made of the porous Ce0.94Zr0.06O2 nano-sheets showed a higher sensitivity (87–100 ppm NH3) and a lower detection limit (100 ppb) at room temperature than the sensors made of pure CeO2 nano-sheets prepared using the similar process. And they exhibited good selectivity, reproducibility and long-term stability to NH3 detection at room temperature

Ultrafine Mn3O4 nanowires synthesized by colloidal method as electrode materials for supercapacitors with a wide voltage range

Manganese oxide is considered an ideal pseudo-capacitive electrode material for supercapacitors due to its low cost, environmental friendliness and large theoretical capacity. However, it is difficult to obtain manganese electrodes with a high specific capacitance and a large voltage range. In this study, ultrafine Mn3O4 nanowires with an average diameter of 4.0 nm were synthesized using a colloidal method. They have a large specific surface area of 175.1 m2 g−1, and can provide numerous active sites to enhance their specific capacitances. They also show a large pore volume of 0.7960 cm3 g−1, which can provide essential channels for ion transport during charging and discharging processes. The supercapacitor electrode made of these ultrafine Mn3O4 nanowires exhibits a predominant surface capacitive behavior during charge/discharge processes, and achieves a large specific capacitance of 433.1 F g−1 at a current density of 0.5 A g−1 with a very wide voltage range from -0.5 to 1.1 V in 1 M Na2SO4 electrolyte. An asymmetric supercapacitor (ASC) was assembled using a cathode electrode made of these ultrafine Mn3O4 nanowires and an active carbon (AC) anode electrode, and a high energy density of 26.68 Wh kg−1 at a power density of 442 W kg−1 was achieved. The ASC showed a good cycling stability, and its capacitance value was still maintained at 75.8% after 64,000 charge/discharge cycles

Hierarchically nanostructured Zn0.76C0.24S@Co(OH)2 for high-performance hybrid supercapacitor

It is a great challenge to achieve both high specific capacity and high energy density of supercapacitors by designing and constructing hybrid electrode materials through a simple but effective process. In this paper, we proposed a hierarchically nanostructured hybrid material combining Zn0.76Co0.24S (ZCS) nanoparticles and Co(OH)2 (CH) nanosheets using a two-step hydrothermal synthesis strategy. Synergistic effects between ZCS nanoparticles and CH nanosheets result in efficient ion transports during the charge-discharge process, thus achieving a good electrochemical performance of the supercapacitor. The synthesized ZCS@CH hybrid exhibits a high specific capacity of 1152.0 C g-1 at a current density of 0.5 A g-1 in 2 M KOH electrolyte. Its capacity retention rate is maintained at ∼ 70.0% when the current density is changed from 1 A g-1 to 10 A g-1. A hybrid supercapacitor (HSC) assembled from ZCS@CH as the cathode and active carbon (AC) as the anode displays a capacitance of 155.7 F g-1 at 0.5 A g-1, with a remarkable cycling stability of 91.3% after 12,000cycles. Meanwhile, this HSC shows a high energy density of 62.5 Wh kg-1 at a power density of 425.0 W kg-1, proving that the developed ZCS@CH is a promising electrode material for energy storage applications

Co-precipitation synthesis of CuCo2O4 nanoparticles for supercapacitor electrodes with large specific capacity and high rate capability

Ultra-fine CuCo2O4 nanoparticles were synthesized using a facile co-precipitation method assisted by NaBH4 and CTAB, and they were explored as supercapacitor electrode material to achieve a large specific capacity and a high rate capability. The synthesized CuCo2O4–250 nanoparticles had a large surface area of 159.6 m2g−1, which provided numerous active sites to enhance their specific capacity. The abundant mesopores with a pore volume of 0.3599 cm3 g−1 effectively provided numerous channels for the electrolyte ions to diffuse onto the active surface of nanoparticles. The CuCo2O4–250 nanoparticles based electrodes exhibited both battery-type and capacitive-type behavior in the charging/discharging processes. It achieved a large specific capacity of 401.2 C g−1 at a current density of 0.5 A g−1 in 2 M KOH electrolyte. Results showed that when the current density was increased from 1 A g−1 to 10 A g−1, a retained specific capacity of 77.5% was achieved, indicating a good rate capability. An asymmetric supercapacitor with CuCo2O4–250 nanoparticles and activated carbon as positive and negative electrodes exhibited a high energy density of 29.5 Wh kg−1 at a power density of 832.6 W kg−1 and a capacity retention of 72.7% at 10 A g−1 after 10,000 cycles

MnCo2O4/Ni3S4 nanocomposite for hybrid supercapacitor with superior energy density and long-term cycling stability

MnCo2O4 is regarded as a good electrode material for supercapacitor due to its high specific capacity and good structural stability. However, its poor electrical conductivity limits its wide-range applications. To solve this issue, we integrated the MnCo2O4 with Ni3S4, which has a good electrical conductivity, and synthesized a MnCo2O4/Ni3S4 nanocomposite using a two-step hydrothermal process. Comparing with individual MnCo2O4 and Ni3S4, the MnCo2O4/Ni3S4 nanocomposite showed a higher specific capacity and a better cycling stability as the electrode for the supercapacitor. The specific capacity value of the MnCo2O4/Ni3S4 electrode was 904.7 C g−1 at 1 A g−1 with a potential window of 0–0.55 V. A hybrid supercapacitor (HSC), assembled using MnCo2O4/Ni3S4 and active carbon as the cathode and anode, respectively, showed a capacitance of 116.4 F g−1 at 1 A g−1, and a high energy density of 50.7 Wh kg−1 at 405.8 W kg−1. Long-term electrochemical stability tests showed an obvious increase of the HSC’s capacitance after 5500 charge/discharge cycles, reached a maximum value of ∼162.7% of its initial value after 25,000 cycles, and then remained a stable value up to 64,000 cycles. Simultaneously, its energy density was increased to 54.2 Wh kg−1 at 380.3 W kg−1 after 64,000 cycles

Colloidal synthesis of flower-like Zn doped Ni(OH)2@CNTs at room-temperature for hybrid supercapacitor with high rate capability and energy density

Transition metal oxides and hydroxides are typically applied as electrode materials for supercapacitors, but it is often difficult to achieve both their high power density and energy density simultaneously. Herein, electrodes of flower-like Zn doped Ni(OH)2 combined with carbon nanotubes (i.e., Zn doped Ni(OH)2@CNTs) were in-situ synthesized using a colloidal synthesis method at room-temperature, assisted by cetyltrimethyl ammonium bromide (CTAB) and NaBH4. This electrode exhibits an excellent electrochemical performance, achieving a high specific capacity of 750.5 C g-1 at 0.5 A g-1 and maintaining 72.9% of its initial value when the current density is increased from 1 A g-1 to 10 A g-1. A hybrid supercapacitor (HSC) assembled using the Zn doped Ni(OH)2@CNTs as the positive electrode and an active carbon as the negative electrode exhibits a capacity of 201.7 C g−1 at 1 A g-1 and an energy density of 51.3 Wh kg-1 at a power density of 409.6 W kg-1. After running for 50,000 cycles at a current density of 6 A g-1, the capacity of the HSC becomes 115.8% of its initial value. Moreover, this HSC maintains a high energy density of 29.33 Wh kg-1 at a high power density of 16.5 kW kg-1 after cycling for 50,000 times, which indicates its suitability for energy storage applications