9,100 research outputs found

    The moduli space of matroids

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    In the first part of the paper, we clarify the connections between several algebraic objects appearing in matroid theory: both partial fields and hyperfields are fuzzy rings, fuzzy rings are tracts, and these relations are compatible with the respective matroid theories. Moreover, fuzzy rings are ordered blueprints and lie in the intersection of tracts with ordered blueprints; we call the objects of this intersection pastures. In the second part, we construct moduli spaces for matroids over pastures. We show that, for any non-empty finite set EE, the functor taking a pasture FF to the set of isomorphism classes of rank-rr FF-matroids on EE is representable by an ordered blue scheme Mat(r,E)Mat(r,E), the moduli space of rank-rr matroids on EE. In the third part, we draw conclusions on matroid theory. A classical rank-rr matroid MM on EE corresponds to a K\mathbb{K}-valued point of Mat(r,E)Mat(r,E) where K\mathbb{K} is the Krasner hyperfield. Such a point defines a residue pasture kMk_M, which we call the universal pasture of MM. We show that for every pasture FF, morphisms kM→Fk_M\to F are canonically in bijection with FF-matroid structures on MM. An analogous weak universal pasture kMwk_M^w classifies weak FF-matroid structures on MM. The unit group of kMwk_M^w can be canonically identified with the Tutte group of MM. We call the sub-pasture kMfk_M^f of kMwk_M^w generated by ``cross-ratios' the foundation of MM,. It parametrizes rescaling classes of weak FF-matroid structures on MM, and its unit group is coincides with the inner Tutte group of MM. We show that a matroid MM is regular if and only if its foundation is the regular partial field, and a non-regular matroid MM is binary if and only if its foundation is the field with two elements. This yields a new proof of the fact that a matroid is regular if and only if it is both binary and orientable.Comment: 83 page

    Descartes' rule of signs, Newton polygons, and polynomials over hyperfields

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    We develop a theory of multiplicities of roots for polynomials over hyperfields and use this to provide a unified and conceptual proof of both Descartes' rule of signs and Newton's "polygon rule".Comment: 21 pages. v2: Revised the exposition and organization of the paper, corrected some minor typos. v3: Revised according to referee report, added new reference

    Stress-Induced Cocaine Seeking Requires a Beta-2 Adrenergic Receptor-Regulated Pathway from the Ventral Bed Nucleus of the Stria Terminalis That Regulates CRF Actions in the Ventral Tegmental Area

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    The ventral bed nucleus of the stria terminalis (vBNST) has been implicated in stress-induced cocaine use. Here we demonstrate that, in the vBNST, corticotropin releasing factor (CRF) is expressed in neurons that innervate the ventral tegmental area (VTA), a site where the CRF receptor antagonist antalarmin prevents the reinstatement of cocaine seeking by a stressor, intermittent footshock, following intravenous self-administration in rats. The vBNST receives dense noradrenergic innervation and expresses β adrenergic receptors (ARs). Footshock-induced reinstatement was prevented by bilateral intra-vBNST injection of the β-2 AR antagonist, ICI-118,551, but not the β-1 AR antagonist, betaxolol. Moreover, bilateral intra-vBNST injection of the β-2 AR agonist, clenbuterol, but not the β-1 agonist, dobutamine, reinstated cocaine seeking, suggesting that activation of vBNST β-2 AR is both necessary for stress-induced reinstatement and sufficient to induce cocaine seeking. The contribution of a β-2 AR-regulated vBNST-to-VTA pathway that releases CRF was investigated using a disconnection approach. Injection of ICI-118,551 into the vBNST in one hemisphere and antalarmin into the VTA of the contralateral hemisphere prevented footshock-induced reinstatement, whereas ipsilateral manipulations failed to attenuate stress-induced cocaine seeking, suggesting that β-2 AR regulate vBNST efferents that release CRF into the VTA, activating CRF receptors, and promoting cocaine use. Last, reinstatement by clenbuterol delivered bilaterally into the vBNST was prevented by bilateral vBNST pretreatment with antalarmin, indicating that β-2 AR-mediated actions in the vBNST also require local CRF receptor activation. Understanding the processes through which stress induces cocaine seeking should guide the development of new treatments for addiction

    On a theorem of Lafforgue

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    We give a new proof, along with some generalizations, of a folklore theorem (attributed to Laurent Lafforgue) that a rigid matroid (i.e., a matroid with indecomposable basis polytope) has only finitely many projective equivalence classes of representations over any given field.Comment: 11 page

    On a Theorem of Lafforgue

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    We give a new proof, along with some generalizations, of a folklore theorem (attributed to Laurent Lafforgue) that a rigid matroid (i.e., a matroid with indecomposable basis polytope) has only finitely many projective equivalence classes of representations over any given field.</p

    Lift theorems for representations of matroids over pastures

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    Pastures are a class of field-like algebraic objects which include both partial fields and hyperfields and have nice categorical properties. We prove several lift theorems for representations of matroids over pastures, including a generalization of Pendavingh and van Zwam's Lift Theorem for partial fields. By embedding the earlier theory into a more general framework, we are able to establish new results even in the case of lifts of partial fields, for example the conjecture of Pendavingh–van Zwam that their lift construction is idempotent. We give numerous applications to matroid representations, e.g. we show that, up to projective equivalence, every pair consisting of a hexagonal representation and an orientation lifts uniquely to a near-regular representation. The proofs are different from the arguments used by Pendavingh and van Zwam, relying instead on a result of Gelfand–Rybnikov–Stone inspired by Tutte's homotopy theorem.</p

    Antagonism of GABA-B but not GABA-A receptors in the VTA prevents stress- and intra-VTA CRF-induced reinstatement of extinguished cocaine seeking in rats

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    Stress-induced reinstatement of cocaine seeking requires corticotropin releasing factor (CRF) actions in the ventral tegmental area (VTA). However the mechanisms through which CRF regulates VTA function to promote cocaine use are not fully understood. Here we examined the role of GABAergic neurotransmission in the VTA mediated by GABA-A or GABA-B receptors in the reinstatement of extinguished cocaine seeking by a stressor, uncontrollable intermittent footshock, or bilateral intra-VTA administration of CRF. Rats underwent repeated daily cocaine self-administration (1.0 mg/kg/ing; 14 × 6 h/day) and extinction and were tested for reinstatement in response to footshock (0.5 mA, 0.5” duration, average every 40 s; range 10–70 s) or intra-VTA CRF delivery (500 ng/side) following intra-VTA pretreatment with the GABA-A antagonist, bicuculline, the GABA-B antagonist, 2-hydroxysaclofen or vehicle. Intra-VTA bicuculline (1, 10 or 20 ng/side) failed to block footshock- or CRF-induced cocaine seeking at either dose tested. By contrast, 2-hydroxysaclofen (0.2 or 2 μg/side) prevented reinstatement by both footshock and intra-VTA CRF at a concentration that failed to attenuate food-reinforced lever pressing (45 mg sucrose-sweetened pellets; FR4 schedule) in a separate group of rats. These data suggest that GABA-B receptor-dependent CRF actions in the VTA mediate stress-induced cocaine seeking and that GABA-B receptor antagonists may have utility for the management of stress-induced relapse in cocaine addicts

    Establishing Priorities for Sustainable Environmental Design in the Rural Villages of Yunnan, China

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    This paper addresses sustainable rural village development in China. Rural development is unlike the process of urbanization in Chinese cities and reflects different land ownership rules and different organizational structures. Even though there are an increasing number of Chinese residents in cities, there are still more than 600 million people living in the countryside. The attention lavished on city development has been, in part, now refocused to rural villages. Since 2006, the support for large-scale investment in the countryside has created much change; however, not all of this change is well organized, with potential for less than optimum impacts on the environment and sustainability. The paper identifies the key influences and drivers from historic and contemporary points of view. The sustainability of the villages will derive from long-term self-sufficiency, and this must include the understanding of environmental design principles, which enable suitable dwelling design. Two villages are taken as contrasting examples, and information derived from other sources is discussed. Technologies and techniques that can help determine environmental design priorities are evaluated and directions for future development suggested. This includes development of a design support aid with key drivers of: orientation and site location, window design and key construction features
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