Man-made synthetic receptors for capture and analysis of Ochratoxin A

Contemporary analytical methods have the sensitivity required for Ochratoxin A detection and quantification, but direct application of these methods on real samples can be rarely performed because of matrix complexity. Thus, efficient sample pre-treatment methods are needed. Recent years have seen the increasing use of artificial recognition systems as a viable alternative to natural receptors, because these materials seem to be particularly suitable for applications where selectivity for Ochratoxin A is essential. In this review, molecularly imprinted polymers, aptamers and tailor-made peptides for Ochratoxin A capture and analysis with particular attention to solid phase extraction applications will be discussed

Full vs. partial competitive binding behaviour in molecularly imprinted polymers. The case for a chlorinated phenoxyacids-binding polymer

The parameters governing the binding of a MIP towards a ligand are not conditioned by the presence of other competitors.</p