Dominant control region of the human β- like globin gene cluster

The structure and regulation of the human β -like globin gene cluster has been studied extensively. Genetic disorders connected with this gene cluster are responsible for human diseases associated with high levels of morbidity and mortality, such as β-thalassaemia and sickle cell anaemia. The work described in this thesis is concerned with a novel tissue-specific regulatory element. ... Zie: Summar

Cybraries in paradise: new technologies and ethnographic repositories.

Digital technologies are altering research practices surrounding creation and use of ethnographic field recordings, and the methodologies and paradigms of the disciplines centered around their interpretation. In this chapter we discuss some examples of our current research practices as fieldworkers in active engagement with cultural heritage communities documenting music and language in the Asia- Pacific region, and as developers and curators of the digital repository PARADISEC (the Pacific and Regional Archive for Digital Sources in Endangered Cultures: ). We suggest a number of benefits that the use of digital technologies can bring to the recording of material from small and endangered cultures, and to its re-use by communities and researchers. We believe it is a matter of social justice as well as scientific interest that ethnographic recordings held in higher education institutions should be preserved and made accessible to future generations. We argue that, with appropriate planning and care by researchers, digitization of research recordings in audiovisual media can facilitate access by remote communities to records of their cultural heritage held in higher education institutions to a far greater extent than was possible in the analog age.Australian Research Counci

Crum Woods Boardwalk

This project combines civil and environmental engineering concepts to design, test, and construct a boardwalk in the Crum Woods in order to improve the Crum Woods trail system for the broader Swarthmore community. This project is motivated by a dedication to serve Swarthmore’s community, an appreciation for the Crum Woods trails as cross country runners, and past work experience on conservation crews. The goal is to make the Crum Woods’ trails more sustainable and less susceptible to erosion. The area of focus for this project is a section of trail that commonly floods and becomes too muddy for use, causing pedestrians to have to walk off trail in order to pass. The solution to this problem is to design and construct a raised boardwalk in order to provide a stable and sustainable walking surface, preventing social trail formation and trail widening. The project involves interaction with the Pennsylvania Department of Environmental Protection (DEP), a local professional engineer, and other government agencies to approve the project for installation and to ensure legal compliance. Designs follow U.S. Forest Service trail construction specifications. Parallel with the design process, a structural analysis is completed to validate specifications and design choices, ensuring that the final structure is safe for pedestrian loads. Mechanical, civil, and environmental engineering concepts inform our design, as well as skills gained from our personal work experiences. This project is a collaborative effort as well; assistance from the Swarthmore Arboretum and community including Director of Grounds Jeff Jabco and Horticultural Supervisor Lars Rasmussen was invaluable