Structural Changes and Ferroelectric Properties of BiFeO₃-PbTiO₃ Thin Films Grown via a Chemical Multilayer Deposition Method

Thin films of (1-x)BiFeO3-xPbTiO3 (BF-xPT) with x ~ 0.60 were fabricated on Pt/Si substrates by chemical solution deposition of precursor BF and PT layers alternately in three different multilayer configurations. These multilayer deposited precursor films upon annealing at 700{\deg}C in nitrogen show pure perovskite phase formation. In contrast to the equilibrium tetragonal structure for the overall molar composition of BF:PT::40:60, we find monoclinic structured BF-xPT phase of MA type. Piezo-force microscopy confirmed ferroelectric switching in the films and revealed different normal and lateral domain distributions in the samples. Room temperature electrical measurements show good quality ferroelectric hysteresis loops with remanent polarization, Pr, of up to 18 {\mu}C/cm2 and leakage currents as low as 10-7 A/cm2.Comment: 14 Pages and 6 figure

Role of nonoperative treatment in managing degenerative tears of the medial meniscus posterior root

BACKGROUND: Tears of the medial meniscus posterior root can lead to progressive arthritis, and its management has no consensus. The aim of our study was to evaluate the effect of supervised exercise therapy on patients with medial meniscus posterior root tears. MATERIALS AND METHODS: Between January 2005 and May 2007, 37 patients with this tear verified by magnetic resonance imaging (MRI) and osteoarthritis grade 1–2 by radiographic examination were treated by a short course of analgesics daily for up to 6 weeks and then as required during follow-up, as well as a 12-week supervised exercise program followed by a home exercise program. Final analysis was performed for 33 patients, average age 55.8 (range 50–62) years and average follow-up of 35 (range 26–49) months. Patients were followed up at 3, 6, and 12 months and yearly thereafter using the Lysholm Knee Scoring Scale, Tegner Activity Scale (TAS), and visual analog scale (VAS). The analysis was performed using one-way analysis of variance (ANOVA) and Pearson’s correlation coefficient to determine the relationship between Lysholm score and body mass index (BMI). RESULTS: Patients showed an improvement in Lysholm score, TAS, and VAS, which reached maximum in 6 months and later was accompanied by a decline. However, scores at the final follow-up were significantly better than the pretherapy scores. There was also a progression in arthritis as per Kellgren and Lawrence radiographic classification from median 1 preintervention to median 2 at the final follow-up. A correlation between BMI and Lysholm scores was seen (r = 0.47). CONCLUSION: Supervised physical therapy with a short course of analgesics followed by a home-based program results in symptomatic and functional improvement over a short-term follow-up; however, osteoarthritis progression continues and is related to BMI

An Overview Of Consumer Perceptions And Acceptance As Well As Barriers And Potential Of Electronic Personal Health Records

Healthcare industry leaders, government agencies and the general public are beginning to see the value that Electronic Health Records (EHR) systems bring through increased quality, reduced medical error rates, and improved care coordination. One subset of the EHR, known as the electronic personal health record (PHR), is gaining in popularity. Before PHRs will be widely adopted, many barriers to their use must be overcome. These include the costs to the developer, host, and patient. Patient access to electronic resources is a concern. Interoperability is another problem. It is not practical for physicians to convert different data formats so that different PHRs may be adopted. Finally, privacy and security concerns also impact EHR adoption. Patients want assurance that their data is secure and not used for marketing purposes. Despite these barriers, there is high consumer interest in PHR products. In future, it is expected that PHR programs will be certified, security and privacy will be enforced by legislation, and standards for interoperability will be developed. PHR will also incorporate additional decision support aids and may become part of a social network that promotes peer support for positive behavior change. This paper will provide an overview of all these issues pertaining to PHR

`Zwicky's Nonet': a compact merging ensemble of nine galaxies and 4C 35.06, a peculiar radio galaxy with dancing radio jets

We report the results of our radio, optical and infra-red studies of a peculiar radio source 4C~35.06, an extended radio-loud AGN at the center of galaxy cluster Abell 407 ($z=0.047$). The central region of this cluster hosts a remarkably tight ensemble of nine galaxies, the spectra of which resemble those of passive red ellipticals, embedded within a diffuse stellar halo of $\sim$1~arcmin size. This system (named the `Zwicky's Nonet') provides unique and compelling evidence for a multiple-nucleus cD galaxy precursor. Multifrequency radio observations of 4C~35.06 with the Giant Meterwave Radio Telescope (GMRT) at 610, 235 and 150 MHz reveal a system of 400~kpc scale helically twisted and kinked radio jets and outer diffuse lobes. The outer extremities of jets contain extremely steep spectrum (spectral index -1.7 to -2.5) relic/fossil radio plasma with a spectral age of a few$\,\times (10^7 - 10^8)$ yr. Such ultra-steep spectrum relic radio lobes without definitive hot-spots are rare, and they provide an opportunity to understand the life-cycle of relativistic jets and physics of black hole mergers in dense environments. We interpret our observations of this radio source in the context of the growth of its central black hole, triggering of its AGN activity and jet precession, all possibly caused by galaxy mergers in this dense galactic system. A slow conical precession of the jet axis due to gravitational perturbation between interacting black holes is invoked to explain the unusual jet morphology.Comment: Published in MNRAS | No. of pages 12, 10 figures and 4 tables. Comments are welcom

Health Care Organization Managers Beware-Understand Your Ethical Constraints

Review of the book Business Ethics in Healthcare: Beyond Compliance.(2001). Leonard J. Weber. Bloomington: Indiana University Press. 196 pp

The comparative effects of Itopride and Levosulpiride orally used in patients suffering from Non-ulcer dyspepsia

Background: Itopride and Levosulpiride both comes under the group of Prokinetic drugs. These drugs are used for the treatment of non-ulcer dyspepsia, heart burn, nausea and vomiting. Both drugs act on dopaminergic D2 receptor as antagonist and increases the concentration of acetylcholine so that gastric peristalsis will be increase and that time pressure at lower oesophageal sphincter will be increase thus gastric motility increases and there will be good gastro-duodenal co-ordination.Method: This study has to conduct on patients with complains of non-ulcer dyspepsia attended Medical outdoor and department of pharmacology of SKMCH Muzaffarpur, Bihar, India. The total 60 patients have to include in the study, which have to randomly divide in two groups. Group A (itopride) comprising of 30 patients and Group B (Levosulpiride) comprising of 30 patients. Patients have to randomly allocate to receive one tablet of itopride hydrochloride, 50 mg three times daily before meal and one tablet Levosulpiride of 75 mg three times daily before meal. Authors have to enroll the patients at the interval of two weeks and continue it upto 3 months.Results: Study did not found any remarkable change in biochemistry profile. Only QT prolongation changes were found in two patients, but no serious cardiac toxicity was observed with patient receiving Levosulpiride. Neither QT prolongation nor serious cardiac toxicity was observed with itopride hydrochloride therapy.Conclusions: In present study, efficacy of Itopride was comparable to Levosulpiride in relieving the symptoms of non-ulcer dyspepsia. Both the drugs were clinically and biochemically well tolerated. QT prolongation changes were found in two patients, but no serious cardiac toxicity was observed with patient receiving Levosulpiride. Itopride does not show cardiac toxicity and any changes in ECG

Entanglement islands and cutoff branes from path-integral optimization

Recently it was proposed that, the AdS/BCFT correspondence can be simulated by a holographic Weyl transformed CFT$_2$, where the cut-off brane plays the role of the Karch-Randall (KR) brane \cite{Basu:2022crn}. In this paper, we focus on the Weyl transformation that optimizes the path integral computation of the reduced density matrix for a single interval in a holographic CFT$_2$. When we take the limit that one of the endpoint of the interval goes to infinity (a half line), such a holographic Weyl transformed CFT$_2$ matches the AdS/BCFT configuration for a BCFT with one boundary. Without taking the limit, the induced cutoff brane becomes a circle passing through the two endpoints of the interval. We assume that the cutoff brane also plays the same role as the KR brane in AdS/BCFT, hence the path-integral-optimized purification for the interval is in the island phase. This explains the appearance of negative mutual information observed in \cite{Camargo:2022mme}. We check that, the entanglement entropy and the balanced partial entanglement entropy (BPE) calculated via the island formulas, exactly match with the RT formula and the entanglement wedge cross-section (EWCS), which are allowed to anchor on the cutoff brane.Comment: 43pages,comments welcome;V2 major revision; minor revision,JHEP versio

How to Incorporate Molecular Data in Cytopathology Reports

Publisher Copyright: © 2021 by the authors.Serous effusion cytology is widely employed in the initial evaluation of the etiology of effusions with a high diagnostic sensitivity. To standardize practices, The International System for Reporting Serous Fluid Cytology (TIS) was developed following best international practices, the most up-to-date literature, and expert consensus. In the context of this system, ancillary techniques play an important role. Besides defining basic principles in laboratory specimen handling, adequacy criteria, and a standardized reporting terminology with five diagnostic categories, TIS provides an actionable framework for using immunohistochemical and molecular testing in effusion samples, namely, in atypical, suspicious of malignant samples. For diagnostic purposes, these tests may be employed to distinguish between a primary and secondary neoplasm, to confirm a diagnosis of malignant mesothelioma vs. reactive mesothelial hyperplasia, and to correctly classify and determine the primary location of a metastasis. Theranostic molecular tests may also be used for these samples to evaluate potential therapeutic targets. Pathologists play a central role in guiding this process by determining adequacy and selecting appropriate ancillary tests. The activity in this area of research should increase in the near future as new therapeutic targets are discovered and new drugs enter the clinical practice.publishersversionpublishe