Metastatic osteogenic sarcoma or multifocal osteosarcoma: A case report

Multifocal osteosarcoma is a rare condition in which multiple osteogenic sarcoma at various regions are present at diagnosis. These account for 1-3 percent of all osteogenic sarcoma. A thirteen-year-old female presented with pain and swelling over her right thigh for a duration of three months with no history of trauma. The diagnosis of osteosarcoma was suspected through radiology which incidentally also showed the other femur to have involvement while getting the MRI scan. A suspicion of either metastatic osteogenic sarcoma or multifocal osteosarcoma was made and CT of the chest was done to look for pulmonary metastasis. The diagnosis was confirmed by biopsy from the right thigh. The diagnosis was confirmed as metastatic osteogenic sarcoma. There is always suspicion whether these tumors represent osseous metastasis or are of multicentric origin. This case is of interest because there was high suspicion that it could be multifocal osteosarcoma which would have been a very rare case. </jats:p

How to avoid the violation of ethics in research and publication?

Not available</jats:p

Academic journal indexes and metrics: What are they?

Not available.</jats:p

Primitive Neuroectodermal Tumour of Subcutaneous Tissue Presenting as a Shoulder Lump: A Case Report

Primitive neuroectodermal tumour is a poorly differentiated small round cell neoplasm that primarily affects children and is very rarely seen in adults. Peripheral primitive neuroectodermal tumours are rare compared to the central type and resemble soft tissue sarcoma. Primitive neuroectodermal tumours involving the subcutaneous tissue are rare and only a few cases involving the subcutaneous tissue of the anterior abdominal wall have been reported. However, no cases involving the subcutaneous tissue of the shoulder region have been reported. We report the case of a peripheral primitive neuroectodermal tumour arising from subcutaneous tissue of the right shoulder in a young adult.</jats:p

Primitive Neuroectodermal Tumour of Subcutaneous Tissue Presenting as a Shoulder Lump: A Case Report

Primitive neuroectodermal tumour is a poorly differentiated small round cell neoplasm that primarily affects children and is very rarely seen in adults. Peripheral primitive neuroectodermal tumours are rare compared to the central type and resemble soft tissue sarcoma. Primitive neuroectodermal tumours involving the subcutaneous tissue are rare and only a few cases involving the subcutaneous tissue of the anterior abdominal wall have been reported. However, no cases involving the subcutaneous tissue of the shoulder region have been reported. We report the case of a peripheral primitive neuroectodermal tumour arising from subcutaneous tissue of the right shoulder in a young adult

Primitive Neuroectodermal Tumour of Subcutaneous Tissue Presenting as a Shoulder Lump: A Case Report

Primitive neuroectodermal tumour is a poorly differentiated small round cell neoplasm that primarily affects children and is very rarely seen in adults. Peripheral primitive neuroectodermal tumours are rare compared to the central type and resemble soft tissue sarcoma. Primitive neuroectodermal tumours involving the subcutaneous tissue are rare and only a few cases involving the subcutaneous tissue of the anterior abdominal wall have been reported. However, no cases involving the subcutaneous tissue of the shoulder region have been reported. We report the case of a peripheral primitive neuroectodermal tumour arising from subcutaneous tissue of the right shoulder in a young adult

Ocular morbidity among children of Baglung, Nepal

Background: Development of the visual system occurs during childhood and is completed by eight years of life. Ocular disorders occurring during this period can lead to visual impairment which can have a lifelong impact on the life of the child. Early detection and treatment of ocular problems among children minimizes the risk of visual impairment and amblyopia.&#x0D; Objectives: This study aimed to determine the pattern of ocular morbidity among children attending the health camp in Baglung.&#x0D; Methodology: This was a descriptive cross-sectional study conducted to determine the pattern of ocular morbidity among children in the western region of Nepal, Baglung district. The study was conducted in the month of December 2019 for 2 days after receiving ethical approval. All data obtained were analyzed according to age, sex and pattern of ocular morbidity and were expressed in frequency, percentage and mean as applicable. Convenience sampling technique was used.&#x0D; Results: Five hundred and thirty two children were evaluated in the study. Among them, 143 (26.87%) had ocular morbidity. The mean age of children with ocular morbidity was 9.6± 5.4 years. The total male to female ratio was 1.18:1 and that amongst those with ocular morbidities was seen to be 2.04:1.1. The most common ocular morbidity was refractive error in 43(8.08%) followed by conjunctival in 32(6.01%) and lid disorders in 29(5.45%) respectively.&#x0D; Conclusion: Most of the morbidities observed were either preventable or treatable, therefore, eye health camp is an effective method to identify them.</jats:p

Magnetic resonance imaging in Kallmann syndrome: A case report

Kallmann syndrome is a rare genetically inherited condition characterized by hypogonadotrophic hypogonadism and anosmia or hyposmia. It is due to failure of migration of gonadotrophic releasing hormone neuron and olfactory neuron to hypothalamus. This case reports a 39-year-old Maldivian adult with clinical features of Kallmann syndrome and magnetic resonance imaging brain showing absence of olfactory sulcus and bulb.</jats:p

Hearing outcome following ossicular reconstruction for incus defects using partial ossicular replacement prosthesis

Background: Situation of incus erosion is common while performing tympanoplasties for cases of chronic otitis media. As none of the available techniques is said to be gold standard, a cost effective and easily available partial ossicular replacement prosthesis is employed and the postoperative hearing outcome is presented.&#x0D; Objectives: To assess the hearing results of ossiculoplasty using partial ossicular replacement prosthesis (PORP) during tympanoplasty.&#x0D; Methodology: A descriptive cross-sectional study was carried out in a tertiary referral hospital of Nepal from June 2018 to September 2019. Thirty consecutive patients who underwent tympanoplasty for chronic otitis media (inactive/mucosal) with incudostapedial discontinuity were operated using polytetrafluroethylene partial ossicular replacement prosthesis without removing the incus. Pure tone averages, air-bone gap (ABG) and air conduction gain were calculated pre and post-operatively.&#x0D; Results: There was no extrusion of prosthesis. The post-operative air-bone gap less than 20 dB was achieved in 23 (77%) cases. All the patients had post-operative air-bone gap of ≤25 dB. There were no major complications.&#x0D; Conclusion: Polytetrafluroethylene partial ossicular replacement prosthesis is safe, reliable and efficient alternative for ossiculoplasty when the incus is found to have eroded during tympanoplasty surgery.</jats:p

Assessment of Cardiorespiratory fitness among medical students: A prospective study

Youth’s physical activity and level of fitness decline mostly between adolescence and early adulthood. As a result, as the youths get older, non-communicable diseases rise. Medical students, who are assumed to have an extensive understanding of physical exercise and its benefits, are now less active than they were before attending graduate school. This study aimed to assess changes in physical fitness and physical activity of students over-time