Hazard ratios (HR) and 95% confidence intervals (95% CI) of mortality related to body mass index (BMI) and waist circumference (WC) for non-smokers.

*<p>Restricted model: Time-dependent BMI (continuous and quadratic term) or WC (continuous) plus age, sex, smoking (no, yes), Chagas disease (no, yes), log-transformed creatinine (continuous), log-transformed BNP levels (continuous), major ECG abnormalities (no, yes), physical activity within the last 90 days (no, yes), household income (<4, 4–10, ≥10 minimum wage), and education (never, 1–4, ≥4 years).</p>†<p>Extensive model: Restricted model plus diabetes (no, yes), total cholesterol (continuous), systolic blood pressure (continuous), anti-hypertensive treatment (no, yes).</p>‡<p>BMI and WC together: BMI (continuous and quadratic term), WC (continuous) plus extensive model.</p>§<p>p<0.001; ||p<0.05; all other values p>0.05.</p

Hazard ratios (HR) and 95% confidence intervals (95% CI) of mortality related to body mass index (BMI) and waist circumference (WC) for all participants.

*<p>Restricted model: Time-dependent BMI (continuous and quadratic term) or WC (continuous) plus age, sex, smoking (no, yes), Chagas disease (no, yes), log-transformed creatinine (continuous), log-transformed BNP levels (continuous), major ECG abnormalities (no, yes), physical activity within the last 90 days (no, yes), household income (<4, 4–10, ≥10 minimum wage), and education (never, 1–4, ≥4 years).</p>†<p>Extensive model: Restricted model plus diabetes (no, yes), total cholesterol (continuous), systolic blood pressure (continuous), anti-hypertensive treatment (no, yes).</p>‡<p>BMI and WC together: BMI (continuous and quadratic term), WC (continuous) plus extensive model.</p>§<p>p<0.001; ^|| p<0.05; all other values p>0.05.</p

10-year cumulative incidence of death per BMI unit at baseline according to physical activity status.

<p>10-year cumulative incidence of death per BMI unit at baseline according to physical activity status.</p

10-year cumulative incidence of death per BMI unit at baseline according to age groups.

<p>10-year cumulative incidence of death per BMI unit at baseline according to age groups.</p

10-year cumulative incidence of death per BMI unit at baseline according to gender.

<p>10-year cumulative incidence of death per BMI unit at baseline according to gender.</p

10-year cumulative incidence of death per BMI unit at baseline.

<p>10-year cumulative incidence of death per BMI unit at baseline.</p

Hazard ratios (HR) and 95% confidence intervals (95% CI) of mortality related to body mass index (BMI) and waist circumference (WC) for participants who survived the first 5 years of follow-up and maintained stable weight.

*<p>Restricted model: Time-dependent BMI (continuous and quadratic term) or WC (continuous) plus age, sex, smoking (no, yes), Chagas disease (no, yes), log-transformed creatinine (continuous), log-transformed BNP levels (continuous), major ECG abnormalities (no, yes), physical activity within the last 90 days (no, yes), household income (<4, 4–10, ≥10 minimum wage), and education (never, 1–4, ≥4 years).</p>†<p>Extensive model: Restricted model plus diabetes (no, yes), total cholesterol (continuous), systolic blood pressure (continuous), anti-hypertensive treatment (no, yes).</p>‡<p>BMI and WC together: BMI (continuous and quadratic term), WC (continuous) plus extensive model.</p>§<p>p<0.001; ||p<0.05; all other values p>0.05.</p

Characteristics of participants with Body Mass Index (BMI) measured at baseline, and comparison according to BMI category.

*<p>P value: Students t test, Pearson's chi-square test for trends and the Kruskal Wallis test for differences between means, frequencies and medians, respectively †Major ECG abnormalities were defined by the following alterations and Minnesota codes (MC): ventricular conduction defect (MC 7.1, 7.2, 7.4, or 7.8); possible old myocardial infarction (MC1.1.x, 1.2.x and 1.3.x and (4.1.x, 4·2, 5·1, or 5·2)), major isolated ST segment and T wave abnormalities (MC 4.1.x, 4.2, 5.1, or 5.2), left ventricular hypertrophy (MC 3.1 and (4.1.x, 4.2, 5.1, or 5.2)), atrial fibrillation (MC 8.3.1, 8.3.3), major atrio-ventricular conduction abnormalities (MC 6.1.1, 6.2.1, 6.2.2, 6.2.3, 6.4.1, 8.6.1, 8.6.2), pacemaker use (MC 6.8.1), other major arrhythmias (MC 8.2.1, 8.2.2, 8.2.3, 8.2.4, 8.3.2, 8.3.4, 8.4.·2), frequent supraventricular and ventricular premature beats (MC 8.1.1, 8.1.2 or 8.1.3) ‡ Leisure physical activity (walking or any other physical exercise) for at least 20–30 min, ≥3–5 times/week § Education: lower category-never studied, intermediate category −<4 school years, higher category −≥4 school years) || Monthly household income in minimum wages (lower category 1–4, intermediate category 4–10, higher category ≥10).</p

Survival rates up to 11-year follow-up for the tertiles of B-type natriuretic peptide (BNP).

<p>Survival rates up to 11-year follow-up for the tertiles of B-type natriuretic peptide (BNP).</p

Estimated 11-year risk of mortality by the models with traditional risk factors only and after addition of CRP and BNP simultaneously.

<p>Estimated 11-year risk of mortality by the models with traditional risk factors only and after addition of CRP and BNP simultaneously.</p