normal mode eigenvalues and spectra from Waves in the Earth’s core. I: mildly diffusive torsional oscillations

Eigenvalues are provided in a 2D array form with row index for decreasing Le, column index for mode index. Eigenmodes are provided and file name indicates Le and mode index

Antarctica: geopolitical challenges and institutional resilience

The success of the Antarctic Treaty regime over more than 60 years provides the opportunity to assess the relationship between the maintenance of national interests and cooperation between Antarctic states. Over these six decades challenges to the Antarctic Treaty and the evolving Antarctic Treaty System have emerged. These challenges have arisen from within the system itself, most notably in the overturing of the proposed convention to regulate mining and its replacement with a comprehensive environmental protection regime. The system has also faced external challenges; a good example being through the “Question of Antarctica” debate within the United Nations General Assembly. Internal and external challenges have been addressed and, in many ways contributed to revitalising the regime, through adroit diplomacy and enduring commitment to sustaining the Treaty’s principles. This provides the key to the paper’s central argument that system resilience and adaptability has been undervalued in contemporary framings of Antarctic geopolitics that have in recent years tended to highlight tensions and divergent views

Learning clinical skills in the simulation suite: the lived experiences of student nurses involved in peer teaching and peer assessment

SummaryBackground The benefits of peer teaching and assessment are well documented within nurse education literature. However, research to date has predominantly focused on the advantages and disadvantages for the inexperienced learner, with a dearth of knowledge relating to the perceptions of senior nursing students involved in teaching their peers. Aim This study sought to investigate the student experience of taking part in a peer teaching and assessment initiative to include the perceptions of both first year nursing students and second/third year participants. Method Data were collected via open-ended questionnaires and analysed with qualitative Framework analysis. Findings This initiative received a generally positive response both from students being taught and also from those acting as facilitators. Perceived benefits included the social learning experience, development of teaching skills, self-awareness and the opportunity to communicate both good and bad news. Suggestions for improvement included additional time working in small groups, specific supplementary learning materials and the introduction of peer teaching and assessment into other areas of the Adult Nursing Programme. Conclusions Peer teaching and assessment principles represent valuable strategies which can be utilised in nurse education to develop clinical skills and prepare nurses for real-life scenarios. Further research needs to investigate how to enhance the student learning experience and to fully exploit the potential for simulated experience to prepare students for their future role as registered nurses in clinical practice.</p

Normal mode spectra from Waves in the Earth’s core. II: diffusive magneto–Coriolis modes

Eigenvalues are provided in a 2D array form with row index for decreasing Le, column index for mode index. Eigenmodes are provided and file name indicates Le and mode index

MOESM7 of Clinical expression and antigenic profiles of a Plasmodium vivax vaccine candidate: merozoite surface protein 7 (PvMSP-7)

Additional file 7. Clusters of genes co-expressed between Patient Groups 1 and 4. Normalized read counts from the DESeq2 analysis were used to generate clusters of genes with positively correlated transcription profiles using coseq. 251 DEGs formed six clusters; four clusters with dynamics that clearly distinguish the two patient groups are shown here. Boxplots (left) represent individual patient, shaded by Patient Group; the black line connecting boxplots is the mean expression value of all genes in the cluster. a) MSP-7C is co-expressed with 20 other genes such as PIESP1, PMV, and rhoptry neck protein 3 (RON3, PvP01_1469200). b) MSP-7H is co-expressed with 12 other genes including serine-repeat antigen-1 (SERA, PvP01_0417100), subtilisin-like protease 3 (SUB3, PvP01_1026800), and high molecular weight rhoptry protein 3 (RhopH3, PvP01_0703800). c) A gametocyte-specific marker, gamete release protein (PvP01_0115300), was co-expressed with TRAG28 and PHISTc, but negatively correlated with PvMSP-7H and other invasion related genes. d) Another gametocyte-specific marker, gamete antigen 27/25, was co-expressed with Plasmodium exported protein (PHIST, PvP01_0734900) and tryptophan-rich protein 18 (TRAG18, PvP01_1033900). The line graphs (right) show the expression pattern of each gene in the cluster across all patients, and specific genes are labelled. Pearson’s correlation coefficient (r) for abundance values of MSP-7H and these selected genes are shown

MOESM2 of Clinical expression and antigenic profiles of a Plasmodium vivax vaccine candidate: merozoite surface protein 7 (PvMSP-7)

Additional file 2. Principal component analysis (PCA) of ten clinical isolates based on transcriptome-wide single nucleotide polymorphisms (SNPs). RNA-seq data for each clinical isolate was mapped to the P. vivax PvPO1 reference genome (5838 genes) and SNPs (N = 42,988) were extracted using the Genome Analysis Toolkit, version 3.7. SNPs were filtered using the linkage disequilibrium pruning method and PLINK version 1.9. A sliding window size of 50 was set across the transcriptome, advancing with steps of five SNPs, and SNPs with a threshold value above 0.5 were removed. Isolate identity and Patient Groups are labelled. Geographical origin is denoted by coloured symbols: red circle (Yala), blue square (Ubon Ratchathani)

MOESM9 of Clinical expression and antigenic profiles of a Plasmodium vivax vaccine candidate: merozoite surface protein 7 (PvMSP-7)

Additional file 9. A spreadsheet describing the layout of all 1173 peptides contained on the custom peptide microarray. Peptide map of 13 MSP7 protein sequences elongated with neutral GSGSGSG linkers at the C- and N-terminus and translated into overlapping peptides, with peptide length of 15 amino acids and peptide overlap of 11 amino acids. Green and red peptides denote positive controls