13 research outputs found

    Additional file 2: of NGS-based phylogeny of diphtheria-related pathogenicity factors in different Corynebacterium spp. implies species-specific virulence transmission

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    Detected tox, dtxR, prophage and PAI coordinates, annotations and GC content (Table S3): For each of the 137 isolates, coordinates of tox and dtxR genes are given along with their species affiliation and their tox status analysed by qPCR and modified Elek test. All detected prophage sequences and PAIs are shown one line per region. For prophages and PAIs, information about region type and their overlapping or non-overlapping behavior in regard to the tox gene is indicated. For detected prophages, results from the prophage annotation software PHASTER [31] are given. For the alternative PAI, genomic start coordinates of the individual CDS sequences and structural annotations are indicated as well. Average GC content of the draft genome and the specific prophage/PAI regions is given. (XLSX 88 kb

    Additional file 1: of Recurrent evolution of host and vector association in bacteria of the Borrelia burgdorferi sensu lato species complex

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    S1. Strains included in this study, date of isolation, biological source, MLST sequence type (ST), geographic origin and previously determined species designation. S2. Phylogenetic inference including outgroup B. duttonii. S3. Estimates of divergence in generations for Borrelia genospecies. S4. Genes showing nucleotide diversity (π) (Nei 1987) or Tajima’s D (Tajima 1989) values exceeding two standard deviations in each species with respect to the 114 genes under study. S5. Additional material and methods: Phylogeny reconstruction and recombination estimation for three genes in 12 reference Borrelia species. S6. Four-Gamete analysis of loci used by Morlon et al. [18]. S7. Phylogenies reconstructed with BEAST v1.7.5 of a) three genes studied by Morlon et al. [18] combined, b) fla, c) groEL and d) rrs. (PDF 460 kb
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