Definition of target radiological responses.

<p>Definition of target radiological responses.</p

Expected survival of three hypothetical patients.

<p>Base on the equation in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0082225#pone-0082225-t004" target="_blank">Table 4</a>, the expected survival probability can be calculated in individual patients with score 2.1, 2.6, and 3.1, respectively.</p

Patient baseline demographics and tumor characteristics.

<p>[interquartile range] are shown. HBV, hepatitis B virus; HCV, hepatitis C virus; NASH, Non-alcoholic steatohepatitis; MELD, the model for end stage liver disease; CRP, C-reactive protein; AFP, a-fetoprotein. Number (proportion) or median </p

The survival probabilities among patients with good, fair and poor prognosis.

<p>Kaplan–Meier curves were generated to compare survival among patients with good, fair, and poor prognosis defined by the score according to the model at one month post-SIRT.</p

Calculation of Probability of Survival According to the Risk Score.

<p>₀ (t) gives the estimated survival probabilities for a patient with a risk score of 2.6 which is the mean risk score of the whole patients in this study. To calculate the probability of survival at t months of a given patient use the following equation: S(t) = S₀(t)^{exp(score−2.6)}. S</p

The overall survival in the whole series.

<p>Kaplan–Meier curves were generated to show the overall survival of the whole HCC patients after SIRT.</p

Kaplan–Meier curves were generated to compare survival between PR, SD, and PD according to three radiological assessment methods.

<p>HCC patients undergoing SIRT had radiological responses, as evaluated by three criteria: (A) RECIST 1.1, (B) mRECIST, and (C) Choi, carried out at one month post-SIRT.</p

Graphical illustration of Pearson’s product moment correlation of SUV_max vs. ADC _aver.

<p>The scatter plot demonstrates a weak negative correlation between SUV_max and ADC_aver (R = −0.24), which is statistically not significant (p = 0.179).</p

Patient with a biopsy proven prostate cancer of the right transitional zone (Gleason score 3+4 = 7).

<p>Images from simultaneous [¹⁸F] choline PET/MRI. A) T2-weighted image showing an ill-defined hypo-intense lesion of the right transitional zone. B) Diffusion-weighted image at a b-value of 1000 displaying a hyper-intense signal within the lesion indicating restricted water diffusion. C) ADC map with a corresponding hypo-intensity of the lesion. D) PET image showing a focal uptake of (18F) choline of the lesion. E) Fused MRI/PET image.</p

Univariate and Multivariate Analyses of Risk Factors for Survival.

<p> = viral, 0 = nonviral. Etiology: 1</p><p> = 1, 2 = 2–5, 3 = 5 or greater. Number of nodules: 1</p><p> = <3 cm, 2 = 3–10 cm, 3 = >10 cm. Size: 1</p><p> = PR or CR, 2 = SD, 3 = PD. Choi response: 1</p