23 research outputs found

    Leveraging Islamic Philosophy as a Counterterrorism Strategy

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    Description to be added</p

    Desk-based research completed as part of the BEAUPEEP perceptions of digital badging project

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    A desk based review was completed by consultant Amanda Smith to locate evidence around perceptions of digital badging by a) students, b) staff and c) employers and summarise what the evidence contributed to understandings of how digital badging might be used in higher education settings. The full report and a presentation based on the report created by Alison Fox are available as pdf documents. </p

    'The New Design Nexus'

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    If you're having trouble keeping up with the latest technology, well, you're not alone. In fact, you're probably part of the world's fastest growing demographic, the older IT user. You might even qualify as a new wave 'Silver Surfer'! The boom in ICT, Information and Communication Technology, and the growing number of older people using it, are two of the three biggest influences on design for the future, with the third being sustainability as a global concern. A new book that looks at how design is being shaped by these issues is being launched this Friday as part of the State of Design event currently on in Melbourne.</p

    MOESM1 of Characterization of resistance to a potent d-peptide HIV entry inhibitor

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    Additional file 1. Mutations observed in PIE12-trimer resistant viral pools. Env gene position (pNL4-3 numbering), reference base, and all base calls for control and PIE12-trimer resistance viral populations with a mutation > 10% of the population (with percentage of the base calls for each position colored on a spectrum from low (light pink) to high (red)) are indicated. Additionally, the positions are annotated by their location in Env according to the following categories: known or putative glycosylation site (green), gp120 variable loops (gray), chemokine receptor (co-receptor) binding site (blue), rev-response element (dark gray), gp41 N-trimer (orange), gp41 C-peptide region (light blue), or the Rev coding region included within the env gene (yellow). Eighty-one positions were identified. Of these, 74 conform to our analysis criteria (found in the resistant pool(s) and > 10% different frequency than in the control pool)

    MOESM2 of Characterization of resistance to a potent d-peptide HIV entry inhibitor

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    Additional file 2. SPR sensorgrams for PIE12 monomer binding to IZN36 WT (left panel) or Q577R (right panel), processed in Scrubber2 (BioLogic Software) and used for the equilibrium fit shown in Fig. 2. Six threefold dilutions of PIE12 monomer (617 nM to 2.54 nM) were flowed over the WT surface, and ten threefold dilutions (50 µM to 2.54 nM) were flowed over the Q577R surface. The calculated KD’s are 0.031 µM for WT and 2.0 µM for Q577R

    MOESM3 of Characterization of resistance to a potent d-peptide HIV entry inhibitor

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    Additional file 3. Effect of Q577R on C-peptide Inhibitors. Single-cycle viral infectivity assays in which HIV-1 HXB2 Env (WT and Q577R) pseudotyped HIV-1 with a luciferase reporter was used to infect HOS-LES cells in the absence or presence of six fivefold dilutions of the indicated C-peptide (in quadruplicate). The data are the average of two experiments with the standard deviation in parentheses
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