Number of individuals according to each parameter used for calculation of ELISA test performance.

Number of individuals according to each parameter used for calculation of ELISA test performance.</p

Antibody titers assessed by flow cytometry.

Anti-SLA IgG titers from healthy subjects (HS), cutaneous leishmaniasis patients (CL), Montenegro positive individuals (DTH+) and Chagas disease patients (CD), assessed by flow cytometry. Cut off was determined by a ROC curve containing MFI from CL patients and healthy subjects. MFI, mean fluorescence intensity.</p

Measures of prediction error.

<p>Mean squared error (MSE) in predictions is presented for each model at each forecast horizon (1, 2, and 3 months ahead). Percent change in MSE relative to the null model (∂MSE₀) is presented to measure improvement in prediction accuracy. Improvements greater than 5% relative to the null model are indicated with <b>bold</b> text.</p><p>Measures of prediction error.</p

Performance of ELISA and Flow cytometry tests to diagnose cutaneous leishmaniasis cases.

Performance of ELISA and Flow cytometry tests to diagnose cutaneous leishmaniasis cases.</p

Number of individuals according to each parameter used for calculation of Flow cytometry test performance.

<p>Number of individuals according to each parameter used for calculation of Flow cytometry test performance.</p

Neighbor-Joining classification of 45 alleles of the <i>gp63</i> study fragment found in 41 isolates of <i>L</i>. <i>(V</i>.<i>) braziliensis</i> from Corte de Pedra, Brazil.

Nucleotide sequence alignments and gp63 allele classification employed MEGA 5.0 software. Branch tips correspond to each gp63 fragment allele. Clusters 1 and 2 correspond to the major aggregates, while clades A to D correspond to the secondary aggregates of alleles. Black dots indicate alleles detected among 35 different isolates of L. (V.) braziliensis obtained from ATL patients in Corte de Pedra between 1992 and 2001. White dots indicate alleles in parasites drawn from six different patients of the same area between 2008 and 2011. Percentages at the nodes of the dendrogram consist in bootstrap values.</p

Histopathological findings in canine leishmaniasis ulcers.

(A) Dog 1 Ulcer with intense inflammation 4X. (B) Dog 1 Tissue granulation 20X. (C) Dog 5 Intense inflammation, plasma cells 40X. (D) Dog 26 Granuloma 20X. (E) Dog 1 Necrosis 20X. (F) Dog 2 Fibrosis (4X). (G) Dog 1 Amastigotes inside macrophage (arrow) 10X. (H) Dog 1 Amastigotes inside macrophage (arrow) 100X. (I) Dog 2 Fibrosis in blue (same of F) stained by Masson`s Trichrome 4X.</p

Cutaneous and mucosal lesions caused by <i>Leishmania (Viannia) braziliensis</i>.

The ulcerated lesions suggestive of ATL were located in the scrotal sac (A and B), muzzle (C and D) and ears (E and F), being, for the most part, single lesions, ulcerated or ulcero-crusted and of chronic evolution.</p

Covariate lag selections and model parameter estimates.

<p>The values of the cross correlation function (CCF) between the pre-whitened series are presented alongside parameter estimates in the best-fitting and averaged models according to each information criterion. Significance at the 95% confidence level is indicated with <b>bold</b> text.</p><p>Covariate lag selections and model parameter estimates.</p

Counts of nucleotide/amino acid polymorphisms in nucleic acid/predicted amino acid sequences from 405 base-pairs study fragments of <i>L</i>. <i>(V</i>.<i>) braziliensis gp63</i>.

<p>Columns show data for all forty-five <i>gp63</i> alleles (total) identified and alleles stratified according to clustering analysis depicted in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0163284#pone.0163284.g002" target="_blank">Fig 2</a> (clades A to D).</p