DataSheet_1_Preoperative low muscle mass and malnutrition affect the clinical prognosis of locally advanced gastric cancer patients undergoing radical surgery.zip

BackgroundGastric cancer is a common and highly aggressive malignant tumor of the gastrointestinal tract that poses a serious threat to human life and health. As the clinical symptoms of early gastric carcinoma are not obvious, many patients are diagnosed in the middle or late stages. With the advancement of medical technology, gastrectomy has become a safer surgical procedure, but it still has a high recurrence and mortality rate after surgery. The prognosis of gastric cancer patients after surgery is not only related to tumor-related factors (i.e., tumor stage) but the patient’s nutritional status. This study aimed to investigate the effect of preoperative muscle mass combined with the prognostic nutritional index (PNI) on clinical prognosis in locally advanced gastric carcinoma.MethodsThe clinical data of 136 patients with locally advanced gastric carcinoma diagnosed by pathology and undergoing radical gastrectomy were retrospectively reviewed. To analyze the influencing factors of preoperative low muscle mass and its correlation with the prognostic nutritional index. Patients with both low muscle mass and low PNI (≤46.55) were assigned a score of 2, and those with only one or neither of these abnormalities were assigned a score of 1 or 0, respectively, according to the new prognostic score (PNIS). The relationship between PNIS and clinicopathological characteristics was analyzed. Univariate and multivariate analyses were performed to identify risk factors for overall survival (OS).ResultsLow muscle mass was associated with a lower PNI (P ConclusionsThe combination of muscle mass and the PNI score system can be used to predict the survival outcome of patients with locally advanced gastric cancer.</p

Additional file 1: of Is the presence of HCMV components in CNS tumors a glioma-specific phenomenon?

Table S1. Expression of HCMV proteins and DNA in glioma and non glial tumors of CNS. Figure S1. Nested PCR analysis of HCMV DNA from peripheral blood samples. No HCMV DNA was detected in benign meningioma (lane 1), malignant meningioma(lane 2), PRL pituitary adenoma(lane 3), GH pituitary adenoma(lane 4), ACTH pituitary adenoma(lane 5), cavernous hemangioma(lane 6) and metastatic carcinoma samples(lane 7) (DOCX 41 kb

Details of the 20 Chinese jujube varieties.

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Compositions and contents of phenolic acids and flavonoids in full red stage fruits of 20 Chinese jujube (<i>Ziziphus jujuba</i>) varieties.

Compositions and contents of phenolic acids and flavonoids in full red stage fruits of 20 Chinese jujube (Ziziphus jujuba) varieties.</p

Mobile phase gradient used in ultra-high performance liquid chromatography.

Mobile phase gradient used in ultra-high performance liquid chromatography.</p

Correlations between the different phenolic acids and flavonoids compositions in the 20 Chinese jujube varieties.

* and ** indicate significance at P P < 0.01, respectively.</p

Dynamic changes in the phenolic acids and flavonoids composition of Chinese jujube fruits at different development stages.

Dynamic changes in the phenolic acids and flavonoids composition of Chinese jujube fruits at different development stages.</p

Different development stages of the <i>Ziziphus jujuba</i> cv. Hupingzao and red stage fruits from the 20 varieties.

Different development stages of the Ziziphus jujuba cv. Hupingzao and red stage fruits from the 20 varieties.</p

Scatterplot of principal component analysis based on phenolic acids and flavonoids composition of 20 jujube varieties.

The four circles indicate the varieties belonging to the top two principal components.</p

Changes in the total phenolic acids and flavonoids content of the fruit of Chinese jujube (<i>Ziziphus jujuba</i>cv. Hupingzao) during development.

Bars with different letters are significantly different (Duncan’s test, P < 0.05).</p