450 research outputs found
Behavior of thin-walled tubes with combined cross-sectional geometries under oblique loading
Hollow tubes are the most important part of any structure because of their load-bearing capacity, lightweight and inexpensive manufacturing cost. One of the methods for improving the performance under quasi-static loading is to vary the cross-sectional shapes. In the real case, structures are seldom subjected to pure axial or pure bending rather they are subjected to a combination of two load cases i.e. oblique loading. In this paper, the circular cross-section was combined with four different polygonal cross-sections namely tetragon, hexagon, octagon and decagon and a total of 13 geometries were obtained. The buckling behavior of each tube was investigated numerically at various angles of inclination. Each tube was modeled in SOLIDWORKS and then was analyzed in ANSYS. Linear buckling code was used for finding the critical load at various angles ranging from 0° to 14°. The overall result was then compared and it was found that the proposed geometry can be a good alternative over conventional circular tubes in terms of load-bearing capacity at angular load
Review of Erbium-doped fiber amplifier
Data communication systems are increasingly employing optical fiber communication systems (OFCS) as the transmission paths for information. Various types of optical amplifiers have been developed in OFCS to amplify optical signals. In particular, the Erbium-doped fiber amplifier (EDFA) is one example of an optical fiber amplifier that is widely known for use in amplifying optical signals. The most significant points in any optical amplifier design are gain and noise figure (NF). They are closely related to each other. Low NF and high gain are the main features for optimum amplifier (Desurvire, 1987). On the other hand, the gain and NF have very strong impact with EDFA’s configurations. Therefore, changes in EDFA’s configuration play very important role during the designing of optical amplifier. The literature shows that there is no study that has been done to review the EDF configuration. Therefore, in this paper we are presenting an overview of most of the EDFA’s configurations that have been proposed in order to provide the researchers with a clear view of what has been done in this field
Green pharma supply chain: a review of existing practices and future directions
Purpose
The pharmaceutical industry is facing significant pressure to tackle antimicrobial resistance (AMR). Other ecological, societal and regulatory pressures are also driving the industry to “go green”. While such a (green) transition could be possible through appropriate green practices’ implementation, the present understanding about it is superficial and vague. A key reason is the lack of green practices’-related studies on pharmaceuticals, which are also insufficiently comprehensive. This knowledge gap is sought to be addressed.
Design/methodology/approach
A systematic literature review (SLR) was conducted with 73 carefully selected articles, then subjected to thematic content analyses for synthesising the relevant themes and sub-themes.
Findings
Around 76 operational-level green practices covering all key stakeholders across the drug lifecycle were identified. It was revealed that designing drugs having accelerated environmental degradability is important to combat AMR. Also, redesigning existing drugs is environmentally more resource-intensive than developing new ones with significant cost-saving potential in solvent recycling and flexible manufacturing, both of which are not common at present. With regards to green-related barriers, stringent quality requirements on drugs (and therefore risks in making relevant green-oriented modifications) and time-consuming and costly regulatory approvals were found to be the key ones.
Practical implications
The operational green practices’ framework developed for individual pharmaceutical supply chain stakeholders could help practitioners in benchmarking, modifying and ultimately, adopting green practices. The findings could also assist policymakers in reframing existing regulations, such as Good Manufacturing Practices or GMP-related, to promote greener drug development.
Originality/value
This work is the first systematic attempt to identify and categorise operational-level green supply chain practices across stakeholders in the pharmaceutical sector.
Highlights
• Biodegradability of drugs is more important than environmental degradability.
• Flexible manufacturing process design (or quality by design) reduces resource wastage.
• Ecopharmacovigilance is effective in combating PIE and AMR-related issues.
• Upstream and downstream coordination is key to greening pharma operations.
• Costly and time-consuming regulatory approval is a key barrier to greening pharma processes
Seed priming: An overview of techniques, mechanisms, and applications
Seed priming is a pre-sowing seed treatment method that has gained significant attention in recent years due to its potential to improve seed germination and early seedling growth. This review article provides a comprehensive overview of seed priming techniques, their underlying mechanisms, and diverse applications in crop production during the recent years. The article introduces the concept of seed priming and its importance in optimizing seed performance, discussing various seed priming techniques including osmotic priming, hydro-priming, hormonal priming, and microbial priming. Each technique is described in detail, outlining the specific procedures and conditions involved, and their advantages and limitations are discussed. The underlying mechanisms of seed priming are explored, elucidating the biochemical, physiological, and molecular changes that occur during seed priming, and the interactions between priming substances and seeds. The article also provides an in-depth analysis of the applications of seed priming, discussing its positive effects on seed germination, seedling vigour, stress tolerance, and its potential for sustainable agriculture. This review article serves as a valuable resource for researchers, scientists and faculties working in the field of seed technological research and progressive farmers who can adopt this technology for enhancing crop yield. This article provides insights into the techniques, mechanisms, and applications of seed priming for optimizing seed performance and enhancing crop productivity in diverse agricultural systems
A comprehensive review on the impact of cervical spondylosis on quality of life and its management through Unani system of medicine: a review
In the Unani system of medicine, cervical spondylosis is categorized under the broad term known as Waja-ul-Mafasil, which encompasses a wide range of joint disorders including inflammatory, non-inflammatory, infectious, metabolic, and other musculoskeletal ailments. Cervical spondylosis specifically refers to the degenerative changes in the intervertebral discs and adjacent vertebrae in the cervical spine, primarily caused by age related wear and tear. Given the limitations and side effects associated with long term conventional treatments and the considerable impact of the condition on an individual’s physical, mental, and social wellbeing many patients explore alternative therapies. Unani medicine offers various treatment strategies, known as Tadabeer, for managing joint related conditions. This literature review aims to evaluate the existing evidence provided by classical Unani scholars and assess clinical studies on the effectiveness of different regimenal therapies in alleviating joint pain through Unani approaches. The review was conducted using databases such as Google Scholar, PubMed, Science Direct, and Medline, along with classical Unani manuscripts accessed from the library of State Unani Medical College, Prayagraj, Uttar Pradesh, India. Considering the inadequacy of conventional medical treatments, Unani medicine presents a promising alternative through its comprehensive methods including dietary regulations, regimenal procedures, and pharmacological interventions for managing cervical spondylosis.
Molecular characterization, cloning and sequencing of coat protein gene of a Pakistani potato leaf roll virus isolate and its phylogenetic analysis
Total RNA was extracted from potato leaf roll virus (PLRV) positive potato plants and complementary DNA were synthesized. Reverse transcriptase polymerase chain reaction (RT-PCR) based detection conditions were optimized by using coat protein (CP) gene specific primers. A 346 bp amplicon of PLRV- coat protein (CP) gene was amplified. Amplified CP-gene of PLRV was cloned in TA cloning vector, PCR ® 2.1. The clone was confirmed subsequently through restriction digestion analysis. PCR amplification used cDNA clone as a template and nucleotide sequencing. Expected nucleotide sequence of amplified PLRV-CP gene show homology of 94 to 97% when compared to the sequences already reported in GenBank database. This explored novel PLRV-CP gene was submitted at NCBI GenBank for characterization of PLRV Pakistani isolate (Accession No. JN039286). Phylogenetic analysis was also carried out and tree was made by using MEGA 4.0.Key words: Potato, potato leaf roll virus (PLRV), coat protein (CP) gene, reverse transcriptase polymerase chain reaction (RT-PCR), PLRV-CP Pakistani isolate
The Effect of Disclosing the Social, Environmental and Economic Dimensions on the Profitability of the Services Sector Companies Listed on the Amman Stock Exchange
Purpose: Examine the influence of disclosing social, environmental, and economic activities on profitability in the services sector on the Amman Stock Exchange.
Theoretical Framework: Explore theoretical underpinnings connecting disclosure of social, environmental, and economic activities to business profitability, drawing from corporate responsibility, sustainability, and financial theories.
Methodology: Utilized a questionnaire distributed to Jordanian service sector firms' auditors and financial managers, employing simple random sampling. Focused on variables related to social, environmental, and economic disclosure.
Findings: Positive link between social disclosure and profitability, attributed to fair service distribution and indirect employee support. Environmental disclosure positively affects profits through resource optimization and reduced pollution. Economic disclosure correlates positively with profitability by influencing pricing and product design.
Conclusion: Disclosing social, environmental, and economic activities significantly impacts profitability in Amman Stock Exchange-listed service sector firms, emphasizing equitable services, resource efficiency, and strategic economic disclosure
Feature Fusion for Human Activity Recognition using Parameter-Optimized Multi-Stage Graph Convolutional Network and Transformer Models
Human activity recognition (HAR) is a crucial area of research that involves
understanding human movements using computer and machine vision technology.
Deep learning has emerged as a powerful tool for this task, with models such as
Convolutional Neural Networks (CNNs) and Transformers being employed to capture
various aspects of human motion. One of the key contributions of this work is
the demonstration of the effectiveness of feature fusion in improving HAR
accuracy by capturing spatial and temporal features, which has important
implications for the development of more accurate and robust activity
recognition systems. The study uses sensory data from HuGaDB, PKU-MMD, LARa,
and TUG datasets. Two model, the PO-MS-GCN and a Transformer were trained and
evaluated, with PO-MS-GCN outperforming state-of-the-art models. HuGaDB and TUG
achieved high accuracies and f1-scores, while LARa and PKU-MMD had lower
scores. Feature fusion improved results across datasets.Comment: 7 pages, 1 figure, conferenc
The contribution of Hassan al-Rammah to gunpowder and rocket technology
The objective of this chapter is to study the early development of gunpowder and rocket technologies in the golden age of the Islamic civilization contributed by aI-Hassan AIRammah and understand his methodology in developing the military sciences and technologies. The methodology adopted in this chapter is a library based research and data is collected from reliable sources and internet sources. The research investigates the role
of Hassan al Rammah in developing the rocket technology in the 13th century. The main focus of the research is to highlight the stages of the development of such a technology
and how it was utilized by the Muslims in their war against the Mongols and the crusades during the 13th . The research explores the technique was used by Al -Rammah for
developing rocket fuel and suitable Gunpowder recipes for cannons, rocket and fireworks. The significance of this research comes from revealing al Hassan al -Rammah effort in
developing weaponry and military's techniques that helped the Muslim to excel in the military technology during the golden age of the Islamic civilization. AI-Hassan AIRammah
(the lancer), a Muslim scholar lived in Syria in the thirteenth century, and died in between 1294-1295A.D AI- Rammah excelled in the military field, he wrote 107 recipes of gunpowder that had been used for rocket, canons and fireworks [Hassan, 2003,p.23]. He wrote treaties entitled: AI-Furusiyya wa AI-Manasib AI-Harbiyya (Book of Military
Horsemanship and Ingenious War Devices) [Zaky, 1967, pA8]. This chapter explores al Hassan al-Rammah's endeavour in developing the rocket technolog
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