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    Supplementary Figures S1-S8 from Epigenetically Regulated Chromosome 14q32 miRNA Cluster Induces Metastasis and Predicts Poor Prognosis in Lung Adenocarcinoma Patients

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    Figure S1. Expression of 14q32 miRNAs in tumor samples from lung adenocarcinoma patients according to EGFR, KRAS and TP53 mutation status. Figure S2. Methylation analysis of imprinting control regions of the 14q32 cluster in lung adenocarcinoma patients. Figure S3. Association of disease-free survival and N stage in never-smoker lung adenocarcinoma patients. Figure S4. Cell viability of lung adenocarcinoma cells after increasing 14q32 miRNA levels by CRISPR activation technology. Figure S5. Differential expression of genes adjacent to the 14q32 miRNA cluster activated by CRISPR activation technology. Figure S6. Association of genes modulated by 14q32 miRNAs with disease-free survival in lung adenocarcinoma patients. Figure S7. Cell viability of lung adenocarcinoma cells after increasing levels of 14q32 miRNAs by transfection of specific miRNA mimics. Figure S8. Validation of the migratory and invasive effects of miR-323b, miR-487a, and miR-539 on lung adenocarcinoma cells with different genetic background.</p
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