249 research outputs found

    Diversity in Harmony: Creating the Built Environment’s Future

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    The research paper investigates the relationship between the architectural history , innovative design and artifical intelligence ( AI) in shaping the built environment of the future. It investigates architects\u27 ongoing efforts to push past design limitations using AI, with a focus on the expressive capacity of historical architectural materials. It addresses the transformation nature of generative design, emphasizing an iterative process using AI tools. The research paper makes a link between generative design as well as emerging forms of architecture by referencing the Dancism Movement using AI Midjourney tool. A case study demonstrates DANCISM Movement patterns, redefining high-rise buildings by means of a dance-like form, while evaluating AI-generated designs and the resulting educational implications. This investigation incorporates to the ongoing discussion concerning AI\u27s transformation role in developing an extensive as well as dynamic architecture in the years to come

    Green Human Resource Management Practices Among Palestinian Manufacturing Firms- An Exploratory Study

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    Organizations are increasingly finding it challenging to balance economic and environmental performance particularly those that face competitive, regulatory and community pressure. With the increasing pressures for environmental sustainability, this calls for the new formulation of strategies by the manufacturers in order to minimize their products and services negative impact on the environment. Hence, Green Human Resource Management (GHRM) continues to be an important research agenda among the researchers. In Palestine, green issues are new and still developing. Constant study is needed to fully understand and update information regarding this area. Objective: The aim of this paper is to explore the views and level of acceptance of GHRM practices among manufacturing firms in Palestine. Results: Through the use of e-mail survey, 121 responses were obtained to generate the results of the study. The result showed GHRM practices have been practiced to somewhat to a greater extent a firms in Palestine. Findings can be extended to study on the issues in further. Academicians and practitioners can apply this result to their research and business strategies on how to improve sustainable performance and to effectively implement GHRM practices

    Determination of metformin hydrochloride in human plasma by UPLC/MS/MS: Application in bioequivalence study

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    Metformin hydrochloride was quantified in human plasma by Ultra Performance Liquid Chromatography with Tandem Mass spectrometric determination (UPLC-MS/MS). The mobile phase used was (Water + 0.1% Formic acid) and (Acetonitrile + 0.1% Formic acid) in the ratio of 80:20 (v:v). An Acquity UPLC HSS T3 1.8 um 2.1×50 mm column was used. The detection was performed on a mass spectrometer (ESI+) using chlorpheniramine as an internal standard. The method was fully validated and it was applied to bioequivalence study of metformin hydrochloride in two brands of the drug with relative bioequivalence of 94.7%

    Psychosocial factors associated with physical activity level among undergraduate students in a public university in Malaysia

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    This cross-sectional study aimed to determine the association of psychosocial factors with physical activity levels among undergraduate students aged 18 to 30 years. A sample of 261 students from Universiti Putra Malaysia (n = 261; 138 males; 123 females) participated in the study. The respondents have been selected through a probability-based cluster sampling. A self-administered questionnaire was used to gather information regarding the socio-demographic characteristics(age, ethnicity, family household number, allowance income, and parent’s monthly income), psychosocial factors (self-efficacy, social support, and perceived benefit), and physical activity levels, which was accessed using Global Physical Activity Questionnaire (GPAQ). Multiple linear regression analysis was performed to determine factors associated with physical activity levels. The highest percentage of respondents (63.2%) were classified as having a moderate physical activity, followed by vigorous (24.9%)and low physical activity (11.9%). The findings of multiple linear regression revealed that self-efficacy (Beta = 0.137, p = 0.049) and physical performance (Beta = 0.193, p = 0.002) were significant predictors of physical activity levels. Therefore, enhancements in self-efficacy and positive perception toward having better physical performance could be used as a strategy to increase physical activity levels among students in the university

    Bilateral Ectopic Hypoplastic Uteri Attached to Bilateral Pelvic Sidewalls in a 21-Year-Old Patient with Primary Amenorrhea: The First Published Report

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    Müllerian duct anomalies (MDAs) encompass a group of anatomical malformations resulting from defective development, fusion, migration, or resorption of Müllerian (paramesonephric) ducts during embryonic life. Herein, we report the first case of an exceedingly uncommon MDA (bilateral ectopic hypoplastic uteri attached to bilateral pelvic sidewalls) in a 21-year-old woman who was referred to our tertiary care center as a case of primary amenorrhea for workup and further management

    Past, Present, and Future Perspectives on the Systemic Therapy for Advanced Hepatocellular Carcinoma (HCC) — A Comprehensive Review

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    Hepatocellular carcinoma (HCC) is the fifth most frequent cancer, the third leading cause of cancer-related mortality, and the first leading cause of death in patients with cirrhosis. Management of primary locally advanced, inoperable, recurrent or metastatic HCC is very challenging and continues to be a topic of controversy. Herein, we shed light on the past, present, and future perspectives on the systemic therapy (hormonal therapy, cytotoxic chemotherapy, and novel molecularly targeted therapy) for management of patients with advanced HCC

    Primary Pleural Benign Myxoid Schwannoma in an 18-Year-Old Female: A Case Report and Literature Review

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    Pleural schwannomas are exceedingly rare neoplasms of the thoracic cavity. To the best of our knowledge, less than 20 cases have been reported in the medical English literature. Herein, we report the case of primary pleural benign myxoid schwannoma in an 18-year-old female. The patient was originally referred to our tertiary care hospital for further management of right adrenal gland mass. Physical examination and all laboratory tests were normal. Contrast-enhanced computed tomography scan showed a 4.2 × 3.2 cm, heterogeneous noncalcified mass involving the right adrenal gland region. The right renal vein and inferior vena cava were intact. There was no pleural effusion, ascites, or lymphadenopathy. No pelvic masses were identified. Patient was scheduled for surgical resection. On laparotomy, the mass was not found in its radiologically expected location, and the right kidney and right adrenal gland were intact. The right-sided lower part of diaphragm was opened, and the mass was interestingly found inside the thorax attached to the pleura, and resected successfully. A final histopathological diagnosis of primary pleural benign myxoid schwannoma was established. At a postoperative 6-month followup, there was no radiological evidence of tumor recurrence. Furthermore, literature review on pleural schwannomas is also presented

    Effect of saffron supplementation on oxidative stress parameters: A systematic review and meta‐analysis of randomized placebo‐controlled trials

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    Oxidative stress (OS), the absence of equilibrium between prooxidants and antioxi dants in the body, has been shown to play a pivotal role in the initiation and pro gression of many diseases. Saffron has been noted for its antioxidant capacity and can be used to improve OS parameters in unhealthy patients. Our aim was to evalu ate the efficacy of saffron supplementation on OS parameters in unhealthy patients in randomized controlled trials (RCTs). We searched Medline, EMBASE, Cochrane CENTRAL, Scopus, and Web of Science without language restrictions for RCTs up until April 2021. Studies were included if they compared any form of saffron sup plementation to placebo or no supplementation on OS parameters in unhealthy pa tients. Using a random-effects model with calculated standardized mean difference (SMD) and 95% confidence intervals (CI), we quantitatively synthesized the data. Heterogeneity was assessed using Cochrane's I 2 values. Ten randomized controlled trials were eligible for this review. Seven were included in the meta-analysis and indicated an association between saffron intake and a statistically significant decrease in malondialdehyde (MDA) levels (SMD: −0.40; 95% CI: −0.63, −0.17; I 2 = 32.6%) and a significant increase in total antioxidant capacity (TAC, SMD: 0.24; 95% CI: 0.05, 0.42; I 2 = 00.0%). Saffron intake was shown to significantly impact MDA and TAC, indicating its beneficial properties in improving OS in unhealthy patients. However, additional RCTs are required to evaluate the effect on other OS parameters.info:eu-repo/semantics/publishedVersio

    Pancreatic Tail Schwannoma in a 44-Year-Old Male: A Case Report and Literature Review

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    Pancreatic schwannomas are exceedingly uncommon neoplasms. According to a recent study in 2012, less than 50 cases of pancreatic schwannoma have been described in the English literature over the past thirty years. The vast majority of pancreatic schwannomas take place in the head and body of pancreas, respectively. Herein, we report the case of pancreatic tail ancient schwannoma in a 44-year-old man who presented with a 4-month history of epigastric pain. On physical examination, epigastric region was moderately tender to palpation without evidence of a palpable mass. All laboratory tests were normal. Contrast-enhanced computed tomography (CT) scan showed a 9.2 × 9.5 × 11.5 cm, huge, and well-defined left suprarenal mass arising either from adrenal gland, pancreas, or retroperitoneum. The mass demonstrated mild heterogeneous enhancement with central cystic/necrotic area. No evidence of distant metastasis was identified. At laparoscopy, the mass was noticed to originate from pancreatic tail. Patient underwent surgical resection of pancreatic tail. Microscopic and immunohistochemical examination of the pancreatic tail specimen showed ancient schwannoma. Patient received no adjuvant therapy. At a postoperative 6-month followup, patient was completely asymptomatic and CT scan imaging showed no evidence of tumor recurrence. Moreover, a literature review on pancreatic schwannomas is presented
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