Deforming Euclidean cone 3-manifolds

Given a closed orientable Euclidean cone 3-manifold C with cone angles less than or equal to pi, and which is not almost product, we describe the space of constant curvature cone structures on C with cone angles less than pi. We establish a regeneration result for such Euclidean cone manifolds into spherical or hyperbolic ones and we also deduce global rigidity for Euclidean cone structures.Comment: Only changes for the grants footnotes have been mad

Almost sure functional central limit theorem for ballistic random walk in random environment

We consider a multidimensional random walk in a product random environment with bounded steps, transience in some spatial direction, and high enough moments on the regeneration time. We prove an invariance principle, or functional central limit theorem, under almost every environment for the diffusively scaled centered walk. The main point behind the invariance principle is that the quenched mean of the walk behaves subdiffusively.Comment: Accepted to the Annales de l'Institut Henri Poincar

Structural and molecular characteristics of axons in the long head of the biceps tendon

The innervation of the long head of the biceps tendon (LHBT) is not sufficiently documented. This is a drawback since pathologies of the LHBT are a major source of shoulder pain. Thus, the study aimed to characterize structurally and molecularly nervous elements of the LHBT. The proximal part of 11 LHBTs was harvested intraoperatively. There were 8 female and 3 male specimens. Age ranged from 66 to 86 years. For structural analyses, nervous elements were viewed in the transmission electron microscope. For molecular characterization, we used general neuronal markers including antibodies against neurofilament and protein gene product 9.5 (PGP9.5) as well as specific neuronal markers including antibodies against myelin basic protein (MBP), calcitonin gene-related product (CGRP), substance P (SP), tyrosine hydroxylase (TH), and growth-associated protein 43 (GAP43). Anti-neurofilament and anti-PGP9.5 visualized the overall innervation. Anti-MBP visualized myelination, anti-CGRP and anti-SP nociceptive fibers, anti-TH sympathetic nerve fibers, and anti-GAP43 nerve fibers during development and regeneration. Immunolabeled sections were analyzed in the confocal laser scanning microscope. We show that the LHBT contains unmyelinated as well as myelinated nerve fibers which group in nerve fascicles and follow blood vessels. Manny myelinated and unmyelinated axons exhibit molecular features of nociceptive nerve fibers. Another subpopulation of unmyelinated axons exhibits molecular characteristics of sympathetic nerve fibers. Unmyelinated sympathetic fibers and unmyelinated nociceptive fibers express proteins that are found during development and regeneration. Present findings support the hypothesis that ingrowth of nociceptive fibers are the source of chronic tendon pain

The Role of Technology Support Centres in stimulating Entrepreneurship and Innovation in SME Clusters

The Innovative Product Development Centre (IPDC) was established at the University of Wolverhampton in the West Midlands region of the UK with a mission “to help small and medium sized companies improve their business, secure jobs and contribute to the economic regeneration of the West Midlands Region”. Since 2000, the IPDC has helped several hundred enterprises to develop their businesses through innovation and new product development. Demand for help is high, which reflects a healthy desire by the SMEs to innovate. The assistance given is time limited, but its impact on the business is extremely varied. This paper will discuss the role that a university based product development and technology centre can play in supporting a regional agenda for developing entrepreneurship and innovation in SMEs. Using case studies drawn from the experiences of working with SMEs from the West Midlands region, the paper will consider key issues such as: • Entrepreneurial leadership in SMEs • Formalised approaches for managing NPD • Technology support for innovation • Product innovation • Business networks and entrepreneurial clusters The paper will conclude that university based centres like IPDC can play a vital role in regional development programmes by helping minimise the risks for entrepreneurs to develop new products or adopt new process technologies. Importantly, investments in such centres by regional development agencies can be pivotal for stimulating access to new technology for the exploitation of entrepreneurial clusters and creating attractive inward investment opportunities

Plant regeneration from leaf-derived callus cultures of Primrose (Primula vulgaris)

Efficient micropropagation of Primula species is important both for fundamental scientific studies and commercial applications. Primula vulgaris, along with other Primulaceae species, exhibits floral heteromorphy with two distinct forms of hermaphroditic flower. Studies to identify genes that control heteromorphic flower development require propagation of floral mutants, and efficient regeneration is a key requirement for plant transformation. Several species, including P. vulgaris (Huds.) cultivars and P. x polyantha hybrids are important horticultural crops in Europe, USA and Japan and semi-double/double Primula varieties offer a high-end product. Vegetative propagation of sterile double forms, and as a means to increase numbers of inbred parent plants for F1 seed production, is however, slow. Micropropagation offers the most efficient way of increasing these varieties quickly and efficiently. To date most Primula micropropagation protocols require explant material derived from in vitro grown seedlings or use floral parts as donor material with seasonal limitations. Therefore, an effective and efficient protocol was developed for in vitro regeneration of P. vulgaris via indirect organogenesis from adult leaf derived explants. Exposure of leaf explants of P. vulgaris to media containing synthetic cytokinin, thidiazuron (TDZ) and Auxin (NAA or 2,4-D) resulted in undifferentiated cell proliferation and followed by differentiated growth as shoot organogenesis. Silver nitrate improved in vitro callus growth and increased shoot regeneration further, with up to 72% of explants producing shoots. Regenerated plants developed normally and produced normal fertile flowers within 7 months. The system was also successfully applied for the micropropagation of sterile double-flowered P. vulgaris 'Sue Jervis'. The protocol reported here enables propagation of P. vulgaris without seasonal limitation or destruction of valuable parent donor material. The protocol, with further development, has the potential to underpin development of a transformation system for Primula, which would be of value in studies on flower development and disease resistance in laboratory grown plants

Cesaro mean distribution of group automata starting from measures with summable decay

Consider a finite Abelian group (G,+), with |G|=p^r, p a prime number, and F: G^N -> G^N the cellular automaton given by {F(x)}_n= A x_n + B x_{n+1} for any n in N, where A and B are integers relatively primes to p. We prove that if P is a translation invariant probability measure on G^Z determining a chain with complete connections and summable decay of correlations, then for any w= (w_i:i<0) the Cesaro mean distribution of the time iterates of the automaton with initial distribution P_w --the law P conditioned to w on the left of the origin-- converges to the uniform product measure on G^N. The proof uses a regeneration representation of P

Ion Exchange-Precipitation for Nutrient Recovery from Dilute Wastewater

Regulated phosphorus (P) and nitrogen (N) discharges and the cost of fertilizer provide economic drivers for nutrient removal and recovery from wastewater. This study used ion exchange (IX) in dilute (domestic) wastewater to concentrate nutrients with subsequent recovery by struvite precipitation. This is the first tertiary wastewater treatment study directly comparing P removal using a range of Fe, Cu, and Al-based media followed by clinoptilolite IX columns for N removal and precipitation using the combined regenerants. Phosphate removal prior to breakthrough was 0.5–2.0 g P Lmedia−1, providing effluent concentrations −1 PO4-P and −1 NH4-N for ≥80 bed volumes. Dow-FeCu resin provided effective P removal, efficient neutral pH regeneration and 560 mg P L−1 in the regeneration eluate (≥100× concentration factor). Exchange capacity of clinoptilolite in column mode was 3.9–6.1 g N Lmedia−1 prior to breakthrough. Precipitation using the combined cation and anion regenerants resulted in a maximum of 74% P removal using Dow-FeCu. Precipitates contained impurities, including Al3+, Ca2+, and Fe. Overall, the IX-precipitation recovery process removed ≥98% P and 95% N and precipitates contained 13% P and 1.6% N. This sequential process can satisfy increasingly stringent wastewater standards and offers an effective alternative to traditional treatment technologies that simply remove nutrients. Approximately 84% of total P and 97% of total Kjeldahl N entering a treatment plant can be captured (accounting for primary clarifier removal), whereas most existing technologies target side streams that typically contain only 20–30% of influent P and 15–20% of influent N

Bottling Scotland, drinking Scotland: Scotland's future, the whisky industry and leisure, tourism and public-health policy

Single-malt whisky is the product of over one hundred distilleries across Scotland, and is the subject of a number of claims about its status as an ‘authentic’ Scottish drink. The whisky industry in Scotland argues that it creates significant amounts of revenue for Scotland and the United Kingdom – not just in sales of single-malt whiskies and blended whiskies, but also from the contribution of whisky tourism. As such, Scottish policy-makers in tourism and local regeneration have used whisky both as an attraction to market to visitors to the country, and a vehicle for creating jobs. In this paper, the whisky industry and related whisky tourism industry in Scotland is explored alongside an analysis of tourist and local regeneration policies and strategies that explicitly nurture the notion that whisky is a necessary part of Scottish identity. I will then contrast this with policies on leisure that identify alcohol drinking as problematic, and argue that the whisky industry has worked to convince its public sector supporters that drinking single-malt whiskies in distillery visitor centres is harmless, while signing up to campaigns to moderate drinking in the wider Scottish public

Low Temperature Drying With Air Dehumidified by Zeolite for Food Products: Energy Efficiency Aspect Analysis

Developments in low temperature drying of food products are still an interesting issue; especially with respect to the energy efficiency. This research studies the energy efficiency that can be achieved by a dryer using air which is dehumidified by zeolite. Experimental results are fitted to a dynamic model to find important variables for the drying operation. The results show that ambient air temperature as well as the ratio between air flow for drying and air flow for regeneration, affect the energy efficiency significantly. Relative humidity of used air, and shift time have a minor effect on the dryer performance. From the total work, it can be noted that the dryer efficiency operated at 50-60°C achieves 75 percent, which is attractive for drying of food products