Near-infrared spectroscopy using indocyanine green dye for minimally invasive measurement of respiratory and leg muscle blood flow in patients with COPD

Reliability of Near-infrared spectroscopy (NIRS), measuring indocyanine green (ICG) for minimally invasive assessment of relative muscle blood flow during exercise has been examined in fit young individuals, but not in COPD. Here we ask whether it could be used to evaluate respiratory and locomotor muscle perfusion in COPD patients. Vastus lateralis muscle blood flow (MBF, the reference method calculated from arterial and muscle ICG concentration curves) and a blood flow index (BFI, calculated using only the (same) muscle ICG concentration curves) were compared in 10 patients (FEV1:51{plus minus}6%predicted) at rest and during cycling at 25%, 50%, 75% and 100% of WRpeak. Intercostal muscle MBF and BFI were also compared during isocapnic hyperpnea at rest, reproducing ventilation levels up to those at WRpeak. Intercostal and vastus lateralis BFI increased with increasing ventilation during hyperpnea (from 2.5{plus minus}0.3 to 4.5{plus minus}0.7nM/s) and cycling load (from 1.0{plus minus}0.2 to 12.8{plus minus}1.9nM/s), respectively. There were strong correlations between BFI and MBF for both intercostal (r=0.993 group mean data, r=0.872 individual data) and vastus lateralis (r=0.994 group mean data, r=0.895 individual data). Fold changes from rest in BFI and MBF did not differ for either the intercostal muscles or the vastus lateralis. Group mean BFI data showed strong interrelationships with respiratory and cycling workload, and whole body metabolic demand (r ranged from 0.913 to 0.989) simultaneously recorded during exercise. We conclude that BFI is a reliable and minimally invasive tool for evaluating relative changes in respiratory and locomotor muscle perfusion from rest to peak exercise in COPD patient groups

Near-infrared spectroscopy monitoring in cardiac and noncardiac surgery: Pairwise and network meta-analyses

Producción CientíficaGoal-directed therapy based on brain-oxygen saturation (bSo2) is controversial and hotly debated. While meta-analyses of aggregated data have shown no clinical benefit for brain near-infrared spectroscopy (NIRS)-based interventions after cardiac surgery, no network meta-analyses involving both major cardiac and noncardiac procedures have yet been undertaken. Randomized controlled trials involving NIRS monitoring in both major cardiac and noncardiac surgery were included. Aggregate-level data summary estimates of critical outcomes (postoperative cognitive decline (POCD)/postoperative delirium (POD), acute kidney injury, cardiovascular events, bleeding/need for transfusion, and postoperative mortality) were obtained. NIRS was only associated with protection against POCD/POD in cardiac surgery patients (pooled odds ratio (OR)/95% confidence interval (CI)/I2/number of studies (n): 0.34/0.14–0.85/75%/7), although a favorable effect was observed in the analysis, including both cardiac and noncardiac procedures. However, the benefit of the use of NIRS monitoring was undetectable in Bayesian network meta-analysis, although maintaining bSo2 > 80% of the baseline appeared to have the most pronounced impact. Evidence was imprecise regarding acute kidney injury, cardiovascular events, bleeding/need for transfusion, and postoperative mortality. There is evidence that brain NIRS-based algorithms are effective in preventing POCD/POD in cardiac surgery, but not in major noncardiac surgery. However, the specific target bSo2 threshold has yet to be determined.Junta de Castilla y León (project VA161G18

Near-Infrared Colours of Active Galactic Nuclei

We propose near-infrared colour selection criteria to extract Active Galactic Nuclei (AGNs) using the near-infrared Colour-Colour Diagram (CCD) and predict near-infrared colour evolution with respect to redshift. First, we cross-identify two AGN catalogues with the 2MASS Point Source Catalogue, and confirm both the loci of quasars/AGNs in the near-infrared CCD and redshift-colour relations. In the CCD, the loci of over 70 - 80% of AGNs can be distinguished from the stellar locus. To examine the colours of quasars, we simulate near-infrared colours using Hyperz code. Assuming a realistic quasar SED, we derive simulated near-infrared colours of quasars with redshift (up to z ~ 11). The simulated colours can reproduce not only the redshift-colour relations but also the loci of quasars/AGNs in the near-infrared CCD. We finally discuss the possibility of contamination by other types of objects. We compare the locus of AGNs with the other four types of objects (namely, microquasars, CVs, LMXBs, and MYSOs) which have a radiation mechanism similar to that of AGNs. In the near-infrared CCD, each type of object is located at a position similar to the stellar locus. Accordingly, it is highly probable that the four types of objects can be distinguished on the basis of the locus in a near-infrared CCD. We additionally consider contamination by distant normal galaxies. The near-infrared colours of several types of galaxies are also simulated using the Hyperz code. Although galaxies with z ~ 1 have near-infrared colours similar to those of AGNs, these galaxies are unlikely to be detected because they are very faint. In other words, few galaxies should contaminate the locus of AGNs in the near-infrared CCD. Consequently, we can extract reliable AGN candidates on the basis of the near-infrared CCD.Comment: 7 pages, 6 figures, Accepted for publication in A&

Near infrared flares of Sagittarius A*: Importance of near infrared polarimetry

We report on the results of new simulations of near-infrared (NIR) observations of the Sagittarius A* (Sgr A*) counterpart associated with the super-massive black hole at the Galactic Center. The observations have been carried out using the NACO adaptive optics (AO) instrument at the European Southern Observatory's Very Large Telescope and CIAO NIR camera on the Subaru telescope (13 June 2004, 30 July 2005, 1 June 2006, 15 May 2007, 17 May 2007 and 28 May 2008). We used a model of synchrotron emission from relativistic electrons in the inner parts of an accretion disk. The relativistic simulations have been carried out using the Karas-Yaqoob (KY) ray-tracing code. We probe the existence of a correlation between the modulations of the observed flux density light curves and changes in polarimetric data. Furthermore, we confirm that the same correlation is also predicted by the hot spot model. Correlations between intensity and polarimetric parameters of the observed light curves as well as a comparison of predicted and observed light curve features through a pattern recognition algorithm result in the detection of a signature of orbiting matter under the influence of strong gravity. This pattern is detected statistically significant against randomly polarized red noise. Expected results from future observations of VLT interferometry like GRAVITY experiment are also discussed.Comment: 26 pages, 38 figures, accepted for publication by A&

Near-infrared spectroscopy procedure for online determination of sodium and potassium content in low-salt cured hams

Producción CientíficaThis paper reports the development of a near-infrared spectroscopy (NIRS) calibration procedure for the determination of sodium and potassium content in cured ham samples. Sliced samples of hams treated with different salts in different percentages were included in the study. Calibration models developed using partial least squares regression were cross-validated and predictive models were tested using the samples of cured ham with low sodium content. The results showed that the developed NIRS procedure is capable of directly measuring the potassium content of packaged dry-cured ham slices with low sodium content with a fitting accuracy of 91.44%, and that it can indirectly determine the sodium content by applying a correction factor to the values obtained for potassium. The prediction error between the calculated and actual sodium values determined using inductively coupled plasma atomic emission spectrophotometry (ICP-AES) was 0.004%, and this confirms that the NIRS procedure is a viable option for the determination of sodium and potassium content in this type of sample.Apoyo proporcionado por el Departamento de I+D+i y Calidad de GRUPO ALIMENTARIO CAMPOFRÍO S.A

Near-Infrared Imaging of Early-Type Galaxies III. The Near-Infrared Fundamental Plane

Near-infrared imaging data on 251 early-type galaxies in clusters and groups are used to construct the near-infrared Fundamental Plane (FP) r_eff ~ sigma_0^1.53 _eff^-0.79. The slope of the FP therefore departs from the virial expectation of r_eff ~ sigma_0^2 _eff^-1 at all optical and near-infrared wavelengths, which could be a result of the variation of M/L along the elliptical galaxy sequence, or a systematic breakdown of homology among the family of elliptical galaxies. The slope of the near-infrared FP excludes metallicity variations as the sole cause of the slope of the FP. Age effects, dynamical deviations from a homology, or any combination of these (with or without metallicity), however, are not excluded. The scatter of both the near-infrared and optical FP are nearly identical and substantially larger than the observational uncertainties, demonstrating small but significant intrinsic cosmological scatter for the FP at all wavelengths. The lack of a correlation of the residuals of the near-infrared FP and the residuals from the Mg_2-sigma relation indicates that the thickness of these relations cannot be ascribed only to age or metallicity effects. Due to this metallicity independence, the small scatter of the near-infrared FP excludes a model in which age and metallicity effects ``conspire'' to keep the optical FP thin. All of these results suggest that the possible physical origins of the FP relations are complicated due to combined effects of variations of stellar populations and structural parameters among elliptical galaxies.Comment: to appear in The Astronomical Journal; 35 pages, including 13 Postscript figures and 1 table; uses AAS LaTeX style file

Akuisisi Spektrum Near Infrared Reflectance Pada Biji Kakao

Akuisisi spektrum Near Infrared Reflectance Spectroscopy (NIRS) untuk produk olahan kakao telah banyak dilakukan dalam berbagai penelitian namun untuk biji kakao utuh masih belum dilakukan. Tujuan yang ingin dicapai dalam penelitian ini adalah mengembangkan teknik akuisisi spektrum NIRS untuk mendeteksi tingkat fermentasi biji kakao dan menentukan selang panjang gelombang yang mengandung informasi kualitas biji kakao secara nondestruktif. Penelitian ini dilakukan di Pusat Penelitian Kopi dan Kakao Indonesia, Jember-Indonesia dan Georg August University of Göttingen di Göttingen-Jerman pada Juli 2012 sampai Februari 2013. Penelitian menggunakan Multiplicative Scatter Correction (MSC) dan Standard Normal Variate (SNV), Savitzky-Golay smoothing (SGs) dan derivative pertama (D1), derivative kedua (D2) sebagai metode koreksi spektrum dan Principal Component Analysis (PCA) sebagai metode pengolah data spektrum. Hasil penelitian menunjukkan bahwa akuisisi spektrum NIRS pada biji kakao tumpukan mampu menggantikan akuisisi NIRS pada biji kakao individu. NIRS juga diketahui mampu membedakan tingkat fermentasi pada biji dan bubuk kakao. Melalui studi ini ditemukan juga selang panjang gelombang yang dapat mengidentifikasikan kualitas kakao sehingga dapat digunakan untuk penelitian selanjutnya dalam pengembangan model identifikasi kualitas kakao.Kata Kunci: Biji kakao, NIRS, metode nondestruktifNear Infrared Reflectance Spectroscopy (NIRS) spectra acquisition for processed cocoa products has been widely applied in various studies. The application of this method for whole intact cocoa beans is however scarce. The objectives of this research were to develop a spectral acquisition technique of NIRS to detect fermentation level of cocoa beans and determine the wavelength range interval containing cocoa bean quality information nondestructively. This research was performed in Indonesian Coffee and Cocoa Research Institute, Jember-Indonesia for fermentation treatment and Georg-August University of Göttingen, Germany for spectra acquisition. These were conducted from July 2012 to February 2013. Multiplicative Scatter Correction (MSC), Standard Normal variate (SNV), Savitzky-Golay Smoothing (SGS) and spectra transformation into its first and second derivative (D1 and D2 respectively) were used as spectral pre-processing method whilst principal component analysis (PCA) was applied as a method of data processing. The results showed that NIRS spectrum acquisition on bulk of cocoa beans could replace NIRS acquisition on the individual beans. NIRS is able to distinguish the fermentation stages both in cocoa beans and cocoa powder. The study also found several NIR wavelength range interval associated with cocoa quality so that it can be used for further studies to develop cocoa quality attributes prediction models

Near-infrared spectroscopy after high-risk congenital heart surgery in the paediatric intensive care unit

Objective: To establish whether the use of near-infrared spectroscopy is potentially beneficial in high-risk cardiac infants in United Kingdom paediatric intensive care units. Design: A prospective observational pilot study. Setting: An intensive care unit in North West England. Patients: A total of 10 infants after congenital heart surgery, five with biventricular repairs and five with single-ventricle physiology undergoing palliation. Interventions: Cerebral and somatic near-infrared spectroscopy monitoring for 24 hours post-operatively in the intensive care unit. Measurement and main results: Overall, there was no strong correlation between cerebral near-infrared spectroscopy and mixed venous oxygen saturation (r=0.48). At individual time points, the correlation was only strong (r=0.74) 1 hour after admission. The correlation was stronger for the biventricular patients (r=0.68) than single-ventricle infants (r=0.31). A strong inverse correlation was demonstrated between cerebral near-infrared spectroscopy and serum lactate at 3 of the 5 post-operative time points (1, 4, and 12 hours: r=-0.76, -0.72, and -0.69). The correlation was stronger when the cerebral near-infrared spectroscopy was 60%, which was r=-0.50. No correlations could be demonstrated between (average) somatic near-infrared spectroscopy and serum lactate (r=-0.13, n=110) or mixed venous oxygen saturation and serum lactate. There was one infant who suffered a cardiopulmonary arrest, and the cerebral near-infrared spectroscopy showed a consistent 43 minute decline before the event. Conclusions: We found that cerebral near-infrared spectroscopy is potentially beneficial as a non-invasive, continuously displayed value and is feasible to use on cost-constrained (National Health Service) cardiac intensive care units in children following heart surgery

Application of Near Infrared Spectroscopy for the Rapid Assessment of Nutritional Quality of Different Strawberry Cultivars

Strawberry is the most cultivated berry fruit globally and it is really appreciated by consumers because of its characteristics, mainly bioactive compounds with antioxidant properties. During the breeding process, it is important to assess the quality characteristics of the fruits for a better selection of the material, but the conventional approaches involve long and destructive lab techniques. Near infrared spectroscopy (NIR) could be considered a valid alternative for speeding up the breeding process and is not destructive. In this study, a total of 216 strawberry fruits belonging to four different cultivars have been collected and analyzed with conventional lab analysis and NIR spectroscopy. In detail, soluble solid content, acidity, vitamin C, anthocyanin, and phenolic acid have been determined. Partial least squares discriminant analysis (PLS-DA) models have been developed to classify strawberry fruits belonging to the four genotypes according to their quality and nutritional properties. NIR spectroscopy could be considered a valid non-destructive phenotyping method for monitoring the nutritional parameters of the fruit and ensuring the fruit quality, speeding up the breeding program