1,526,824 research outputs found

    Systematic review of birth cohort studies in South East Asia and Eastern Mediterranean regions

    Get PDF
    Few longitudinal studies of children have taken place in the developing world, despite child mortality being concentrated there. This review summarises the methodologies and main outcomes of longitudinal studies of pre-school children (0 to 59 months) in the World Health Organization’s South East Asia (SEA) and Eastern Mediterranean (EM) Regions

    Integrating clinical data from cross-sectional and longitudinal studies

    Get PDF
    Clinical trials are typically conducted over a population in order to illuminate certain characteristics of a health issue or disease process. These cross-sectional studies provide a snapshot of these disease processes over a large population but do not allow us to model the temporal nature of disease. Longitudinal studies on the other hand, are used to explore how these processes develop over time but can be expensive and time-consuming, and only cover a relatively small window within the disease process. This paper explores a technique for integrating cross-sectional and longitudinal studies to build models of disease progression

    COVID-19 and Mental Illnesses in Vaccinated and Unvaccinated People

    Get PDF
    We are very grateful for all the support received from the TPP Technical Operations team throughout this work and for generous assistance from the information governance and database teams at the National Health Service (NHS) England and the NHS England Transformation Directorate. We thank the CONVALESCENCE Study Long COVID PPIE group for their input and for sharing their experiences and expertise throughout the duration of the project.Peer reviewe

    The narrative potential of the British Birth Cohort Studies

    Get PDF
    This paper draws attention to the narrative potential of longitudinal studies such as the British Birth Cohort Studies (BBCS), and explores the possibility of creating narrative case histories and conducting narrative analysis based on information available from the studies. The BBCS have historically adopted a quantitative research design and used structured interviews and questionnaires to collect data from large samples of individuals born in specific years. However, the longitudinal nature of these studies means that they follow the same sample of individuals from birth through childhood into adult life, and this leads to the creation of data that can be understood as a quantitative auto/biography

    Handling Attrition in Longitudinal Studies: The Case for Refreshment Samples

    Get PDF
    Panel studies typically suffer from attrition, which reduces sample size and can result in biased inferences. It is impossible to know whether or not the attrition causes bias from the observed panel data alone. Refreshment samples - new, randomly sampled respondents given the questionnaire at the same time as a subsequent wave of the panel - offer information that can be used to diagnose and adjust for bias due to attrition. We review and bolster the case for the use of refreshment samples in panel studies. We include examples of both a fully Bayesian approach for analyzing the concatenated panel and refreshment data, and a multiple imputation approach for analyzing only the original panel. For the latter, we document a positive bias in the usual multiple imputation variance estimator. We present models appropriate for three waves and two refreshment samples, including nonterminal attrition. We illustrate the three-wave analysis using the 2007-2008 Associated Press-Yahoo! News Election Poll.Comment: Published in at http://dx.doi.org/10.1214/13-STS414 the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http://www.imstat.org

    Simultaneous Detection of Longitudinal and Transverse Bunch Signals at a Storage Ring

    Get PDF
    To understand and control the dynamics in the longitudinal phase space, time-resolved measurements of different bunch parameters are required. For a reconstruction of this phase space, the detector systems have to be synchronized. This reconstruction can be used e.g. for studies of the micro-bunching instability. It occurs if the interaction of the bunch with its own radiation leads to the formation of sub-structures on the longitudinal bunch profile. These sub-structures can grow rapidly -- leading to a sawtooth-like behaviour of the bunch. At KARA, we use a fast-gated intensified camera for energy spread studies, Schottky diodes for coherent synchrotron radiation studies as well as electro-optical spectral decoding for longitudinal bunch profile measurements. For a synchronization, a hardware synchronization scheme is used which compensates for eventual hardware delays. In this paper, the different experimental setups and their synchronization are discussed and first results of synchronous measurements are presented

    Betatron modulation of microwave instability in small isochronous ring

    Full text link
    A novel coupling of the transverse betatron motion to the longitudinal microwave instability is studied. Besides the radial coherent dipole mode space charge field, simulation and theoretical studies in this paper show that the longitudinal coherent dipole mode space charge field due to centroid wiggles also plays an important role in the isochronous regime, it induces betatron oscillation frequencies in temporal evolutions of spectra of longitudinal charge densities, radial centroid offsets and coherent energy deviations of local centroids.Comment: 13 page
    corecore