Reviewing ensemble classification methods in breast cancer

© 2019, Computer Methods and Programs in Biomedicine. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/. This document is the Accepted version of a Published Work that appeared in final form in Computer Methods and Programs in Biomedicine. To access the final edited and published work see https://doi.org/10.1016/j.cmpb.2019.05.019Context: Ensemble methods consist of combining more than one single technique to solve the same task. This approach was designed to overcome the weaknesses of single techniques and consolidate their strengths. Ensemble methods are now widely used to carry out prediction tasks (e.g. classification and regression) in several fields, including that of bioinformatics. Researchers have particularly begun to employ ensemble techniques to improve research into breast cancer, as this is the most frequent type of cancer and accounts for most of the deaths among women. Objective and method: The goal of this study is to analyse the state of the art in ensemble classification methods when applied to breast cancer as regards 9 aspects: publication venues, medical tasks tackled, empirical and research types adopted, types of ensembles proposed, single techniques used to construct the ensembles, validation framework adopted to evaluate the proposed ensembles, tools used to build the ensembles, and optimization methods used for the single techniques. This paper was undertaken as a systematic mapping study. Results: A total of 193 papers that were published from the year 20 0 0 onwards, were selected from four online databases: IEEE Xplore, ACM digital library, Scopus and PubMed. This study found that of the six medical tasks that exist, the diagnosis medical task was that most frequently researched, and that the experiment-based empirical type and evaluation-based research type were the most dominant ap- proaches adopted in the selected studies. The homogeneous type was that most widely used to perform the classification task. With regard to single techniques, this mapping study found that decision trees, support vector machines and artificial neural networks were those most frequently adopted to build en- semble classifiers. In the case of the evaluation framework, the Wisconsin Breast Cancer dataset was the most frequently used by researchers to perform their experiments, while the most noticeable vali- dation method was k-fold cross-validation. Several tools are available to perform experiments related to ensemble classification methods, such as Weka and R Software. Few researchers took into account the optimisation of the single technique of which their proposed ensemble was composed, while the grid search method was that most frequently adopted to tune the parameter settings of a single classifier. Conclusion: This paper reports an in-depth study of the application of ensemble methods as regards breast cancer. Our results show that there are several gaps and issues and we, therefore, provide researchers in the field of breast cancer research with recommendations. Moreover, after analysing the papers found in this systematic mapping study, we discovered that the majority report positive results concerning the ac- curacy of ensemble classifiers when compared to the single classifiers. In order to aggregate the evidence reported in literature, it will, therefore, be necessary to perform a systematic literature review and meta- analysis in which an in-depth analysis could be conducted so as to confirm the superiority of ensemble classifiers over the classical techniques

Neural Networks for the Detection of COVID-19 and Other Diseases: Prospects and Challenges

Artificial neural networks (ANNs) ability to learn, correct errors, and transform a large amount of raw data into beneficial medical decisions for treatment and care has increased in popularity for enhanced patient safety and quality of care. Therefore, this paper reviews the critical role of ANNs in providing valuable insights for patients’ healthcare decisions and efficient disease diagnosis. We study different types of ANNs in the existing literature that advance ANNs’ adaptation for complex applications. Specifically, we investigate ANNs’ advances for predicting viral, cancer, skin, and COVID-19 diseases. Furthermore, we propose a deep convolutional neural network (CNN) model called ConXNet, based on chest radiography images, to improve the detection accuracy of COVID-19 disease. ConXNet is trained and tested using a chest radiography image dataset obtained from Kaggle, achieving more than 97% accuracy and 98% precision, which is better than other existing state-of-the-art models, such as DeTraC, U-Net, COVID MTNet, and COVID-Net, having 93.1%, 94.10%, 84.76%, and 90% accuracy and 94%, 95%, 85%, and 92% precision, respectively. The results show that the ConXNet model performed significantly well for a relatively large dataset compared with the aforementioned models. Moreover, the ConXNet model reduces the time complexity by using dropout layers and batch normalization techniques. Finally, we highlight future research directions and challenges, such as the complexity of the algorithms, insufficient available data, privacy and security, and integration of biosensing with ANNs. These research directions require considerable attention for improving the scope of ANNs for medical diagnostic and treatment applications

Texture and Colour in Image Analysis

Research in colour and texture has experienced major changes in the last few years. This book presents some recent advances in the field, specifically in the theory and applications of colour texture analysis. This volume also features benchmarks, comparative evaluations and reviews

Technology 2002: the Third National Technology Transfer Conference and Exposition, Volume 1

The proceedings from the conference are presented. The topics covered include the following: computer technology, advanced manufacturing, materials science, biotechnology, and electronics

The HBP1 tumor suppressor is a negative epigenetic regulator of MYCN driven neuroblastoma through interaction with the PRC2 complex

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2020, UMaine News Press Releases

This is a catalog of press releases put out by the University of Maine Division of Marketing and Communications between January 2, 2020 and December 15, 2020