Infants ( 1 Month-1 year)

No Abstract

A Month-by-Month Examination of Long-Term Stock Returns

This study provides a month-by-month examination of stock returns. The results reconfirm the January Effect as well as indicate a powerful anomaly in September. Investing in the CRSP equal-weighted index in only January turns $1 in 1926 to$87.40 by 2006. The second closest month is July, during which $1 grows to$3.11. September is a poor month to invest. The $1 invested in only September decreases to a mere$0.49. The Halloween Effect vanishes once the monthly anomalies are controlled for. The September Effect is also established in four out of the five international markets tested

Brazilian Real Crisis Revisited: A Linear Probability Model to Identify Leading Indicators

This article aims at identifying the indicators of the Brazilian real crisis through building a probit model incorporating 20 monthly macroeconomic, political, and financial sector indicators from 1980:1 – 1999:1. Results indicate that the significant variables are inflation (1-month lag), real exchange rate (1-month lag), import growth (1-month lag), US interest rates (2-month lag), public debt/GDP (2-month lag), and current account/GDP (3-month lag). Evidence further indicates that the signs of the variables are in line with our expectations, with the exception of US interest rates.Mexican peso crisis, financial crises, probit model, Brazil

Evaluation of Hepatocellular Carcinoma Transarterial Chemoembolization using Quantitative Analysis of 2D and 3D Real-time Contrast Enhanced Ultrasound.

Quantitative 2D and 3D contrast-enhanced ultrasound (CEUS) was assessed to evaluate early transarterial chemoembolization (TACE) treatment response. Seventeen patients scheduled for TACE for the treatment of hepatocellular carcinoma participated in the study. 2D and 3D CEUS were performed for each patient at three time points: Prior to TACE, 1-2 weeks post TACE, and 1 month post TACE. Peak-intensities of the tumor and surrounding liver tissue were calculated from 2D and 3D data before and after TACE and used to evaluate tumor treatment response. Residual tumor percentages were calculated from 2D and 3D CEUS acquired 1-2 weeks and 1 month post TACE and compared with results from MRI 1 month post TACE. Nine subjects had complete response while 8 had incomplete response. Peak-intensities of the tumor from 3D CEUS prior to TACE were similar between the complete and incomplete treatment groups (p = 0.70), while 1-2 weeks (p \u3c 0.01) and 1 month post treatment (p \u3c 0.01) were significantly lower in the complete treatment group than in the incomplete treatment group. For 2D CEUS, only the peak-intensity values of the tumor from 1 month post TACE were significantly different (p \u3c 0.01). The correlation coefficients between 2D and 3D residual tumor estimates 1-2 weeks post TACE and the estimates from MRI were 0.73 and 0.94, respectively, while those from 2D and 3D CEUS 1 month post TACE were 0.66 and 0.91, respectively. Quantitative analysis on 2D and 3D CEUS shows potential to differentiate patients with complete versus incomplete response to TACE as early as 1-2 weeks post treatment

Early sensitivity to interpersonal timing

Sensitivity to timing in interaction was assessed in mother-infant interaction. In Study 1, three-month-old infants were presented with an image of their mother interacting with them on television, which was either live or temporally delayed by 1 second. Infants detected the temporal delay and were more attentive when the mother was presented live compared to delayed by 1 second. In Study 2, mothers interacted with an image of their three-month-old infant, which was either live or temporally delayed by 1 second. Mothers did not respond to a 1-second delay in their infants' behavior. In Study 3 and 4, the results were replicated with six-month-old infants

Neonates(BIRTH – 1 MONTH)

No Abstract

The Influence of Pain on the Development of PTSD Across the Acute Post Trauma Period

Exposure to potentially traumatic events is fairly common among US adults, yet only a small fraction develops post-traumatic stress disorder (PTSD). It is unclear, however, why some individuals develop PTSD and others do not. Higher pain after a traumatic injury has been associated with higher PTSD symptomology and may be a risk factor for developing PTSD. However, few studies have examined symptoms during the period immediately after a trauma to determine how they relate to PTSD outcome. The goal of this study was to identify trajectories of pain throughout the first month after a traumatic injury and examine their relation to PTSD symptoms at 1 month. A sample of (n = 88) individuals who had experienced a traumatic injury assessed their pain through daily mobile assessments for the first month after injury. Daily mobile assessments consisted of self-report surveys sent to the participants’ mobile device. A follow-up interview was conducted at 1 month after injury to assess PTSD symptomology. Using growth mixture modeling, three trajectories of pain were identified: low pain, decreasing pain, and persistent high pain. Membership to the low pain group was associated with lower PTSD, depression and disability symptoms at 1 month after injury. Membership to the high pain group was associated with higher levels of PTSD, depression and disability symptoms at 1 month. These results demonstrate that there are distinct trajectories of pain after a traumatic injury and these trajectories may relate to later symptoms of psychopathology

Survival and quality of life benefit after endoscopic management of malignant central airway obstruction

Although interventional management of malignant central airway obstruction (mCAO) is well established, its impact on survival and quality of life (QoL) has not been extensively studied.We prospectively assessed survival, QoL and dyspnea (using validated EORTC questionnaire) in patients with mCAO 1 day before interventional bronchoscopy, 1 week after and every following month, in comparison to patients who declined this approach. Material/Patients/Methods: 36 patients underwent extensive interventional bronchoscopic management as indicated, whereas 12 declined. All patients received full chemotherapy and radiotherapy as indicated. Patients of the 2 groups were matched for age, comorbidities, type of malignancy and level of obstruction. Follow up time was 8.0±8.7 (range 1-38) months.Mean survival for intervention and control group was 10±9 and 4±3 months respectively (p=0.04). QoL improved significantly in intervention group patients up to the 6(th) month (p<0.05) not deteriorating for those surviving up to 12 months. Dyspnea decreased in patients of the intervention group 1 month post procedure remaining reduced for survivors over the 12th month. Patients of the control group had worse QoL and dyspnea in all time points.Interventional management of patients with mCAO, may achieve prolonged survival with sustained significant improvement of QoL and dyspnea

Durability of Benefits From Supervised Treadmill Exercise in People With Peripheral Artery Disease.

Background It is currently unknown whether 6 months of supervised treadmill exercise has a durable benefit on 6-minute walk performance, even after exercise is completed, in people with peripheral artery disease. Methods and Results A total of 156 participants with peripheral artery disease were randomized to 1 of 3 groups: supervised treadmill exercise, supervised resistance training, or attention control. Participants received supervised sessions during months 1 to 6 and telephone contact during months 6 to 12. Primary outcomes were change in 6-minute walk distance and short physical performance battery at 6-month follow-up and have been reported previously. Secondary outcomes were change in 6-minute walk and short physical performance battery at 12-month follow-up and are reported here. A group of 134 participants (86%) completed the 12-month follow-up. At 6-month follow-up, compared with control, 6-minute walk distance improved in the treadmill exercise group (+36.1 m, 95% CI =13.9-58.3, P=0.001). Between 6- and 12-month follow-up, 6-minute walk distance significantly declined (-28.6 m, 95% CI=-52.6 to -4.5, P=0.020) and physical activity declined -272 activity units (95% CI =-546 to +2, P=0.052) in the treadmill exercise group compared with controls. At 12-month follow-up, 6 months after completing supervised treadmill exercise, change in 6-minute walk distance was not different between the treadmill exercise and control groups (+7.5, 95% CI =-17.5 to +32.6, P=0.56). There were no differences in short physical performance battery change between either exercise group and control at 6-month or 12-month follow-up. Conclusions A 6-month supervised treadmill exercise intervention that improved 6-minute walk distance at 6-month follow-up did not have persistent benefit at 12-month follow-up. These results do not support a durable benefit of supervised treadmill exercise in peripheral artery disease. Clinical Trial Registration URL : https://www.clinicaltrials.gov . Identifier: NCT 00106327