The Efficacy of Common Prosthetic Joint Infection Prevention Strategies: A Systematic Review

Abstract

Thousands of total hip and knee arthroplasty patients suffer from prosthetic joint infections every year, making them a leading cause of arthroplasty failure. As the number of these procedures continues to grow, so will the healthcare and socio-economic burden of prosthetic joint infections. A comprehensive search for up-to-date literature was completed via the PubMed database, identifying eighteen retrospective and prospective cohort studies that focused on the four prosthetic joint infection prevention methods of interest. Tobacco use cessation of all forms is an efficacious prosthetic joint infection prevention strategy. The common practices of withholding intra-articular injections prior to surgery, using prophylactic single dose cephalosporins, and using the glycemic marker of HbA1c were found to be partially efficacious but require further considerations. Surgeons should be aware of the various considerations involved in validating or discrediting their preferred prevention strategies in order to prevent prosthetic joint infection