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Druggability analysis of shortlisted non-human homologous pathogenic essential proteins.
Abstract
Druggability analysis of shortlisted non-human homologous pathogenic essential proteins.</p- Text
- Journal contribution
- Biophysics
- Biochemistry
- Microbiology
- Pharmacology
- Biotechnology
- Immunology
- Infectious Diseases
- Space Science
- Biological Sciences not elsewhere classified
- Chemical Sciences not elsewhere classified
- Information Systems not elsewhere classified
- predict potent inhibitors
- increasing antimicrobial resistance
- immune simulation analyses
- identify new strategies
- druggable molecule databases
- div >< p
- challenging worldwide owing
- 965 druggable molecule
- identify promising vaccine
- therapeutic targets prioritized
- core proteome data
- based virtual screening
- alternative drug targets
- clostridium difficile </
- difficile </
- designed vaccine
- c </
- vaccinomics approaches
- urgent threat
- subtractive proteomics
- mortality rates
- immunological analysis
- high rates
- high morbidity
- experimental validation
- drug candidates
- dependent nitroreductase
- current study
- conserved residues
- cell epitopes