Malaria drives unique regulatory responses across multiple immune cells during human infection

Boyle, Michelle; Dooley, Nick; Chabikwa, Tinashe; Loughland, Jesicca R; Pava, Zuleima; Hamelink, J; Berry, K; Andrew, Dean; Soon, Megan; Sheela, Nair A; Piera, Kim; Williams, T; Barber, Bridget; Grig, Matt; engwerda, chris; Lopez, A; Anstey, Nick

Malaria drives unique regulatory responses across multiple immune cells during human infection

Authors: Michelle Boyle
Nick Dooley
Tinashe Chabikwa
Jesicca R Loughland
Zuleima Pava
J Hamelink
K Berry
Dean Andrew
Megan Soon
Nair A Sheela
Kim Piera
T Williams
Bridget Barber
Matt Grig
chris engwerda
A Lopez
Nick Anstey
Publication date: 30 November 2024
Publisher
Doi

Abstract

Peripheral blood mononuclear cells (PBMCs) from 6 individuals (age 6-24) with P. falciparum infection and 2 healthy adult endemic controls (ages 20 and 27) were collected before drug treatment (day 0) and at 7 and 28 days after treatment. PBMCs were isolated by Fluorescence-activated cell sorting (FACS) according to the presence or absence of XX signal, and analysed using droplet-based scRNAseq

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ZENODO

oai:zenodo.org:6973241

Last time updated on 08/08/2023

This paper was published in ZENODO.

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