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Residues making up the conserved region in the spike S2 domain.
Abstract
Numbering is based on the SARS-CoV-2 spike protein (PDB ID: 6VXX). (DOCX)</p- Text
- Journal contribution
- Microbiology
- Biotechnology
- Evolutionary Biology
- Immunology
- Infectious Diseases
- Virology
- Biological Sciences not elsewhere classified
- wildtype virus alone
- s2 &# 8217
- predict rbd expression
- deep mutational scanning
- zoonotic coronaviruses point
- represent viable variants
- eliciting antibody responses
- different genera identified
- different combinations
- antibody response
- 2 variants
- 12 coronaviruses
- xlink ">
- variant strains
- significant mutations
- results suggest
- promote evolution
- potential pan
- outbreaks caused
- neural network
- may protect
- may emerge
- higher titers
- generation vaccines
- fusion peptide
- diverse sequences
- coronavirus spikes
- confer protection
- computational model
- combined analyses
- cleavage site
- allowed us
- affinity maturation
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Last time updated on 28/09/2022
This paper was published in The Francis Crick Institute.
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