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The Mann-Whitney U test (M.W.) analysis shows there is no significant differences between mutated groups and non-mutated groups of mutated genes with high mutation rates in the activity of DNA replication (DR) for 10 cancers.
Abstract
The Mann-Whitney U test (M.W.) analysis shows there is no significant differences between mutated groups and non-mutated groups of mutated genes with high mutation rates in the activity of DNA replication (DR) for 10 cancers.</p- Image
- Figure
- Medicine
- Genetics
- Cancer
- Virology
- Biological Sciences not elsewhere classified
- Mathematical Sciences not elsewhere classified
- vital biological processes
- unobserved latent variables
- unobserved confounding biases
- relevant biological processes
- experimental results indicate
- deep variational autoencoder
- higher mutation frequency
- promoting cancer development
- 10 cancer types
- real induce effect
- confounder bias due
- induce cancer initiation
- cancer initiation
- real causality
- certain mutation
- causal effect
- inducing cancer
- driving cancer
- cancer research
- transcriptomic data
- neutral mutations
- necessarily mean
- method quantifies
- mesenchymal transition
- machine learning
- key mutations
- integrating genomic
- genetic mutations
- fundamental goal
- functional changes
- essential events
- efficient method
- cell proliferation
- causal inference
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Last time updated on 24/09/2022
This paper was published in The Francis Crick Institute.
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