Impact of type I IFN-α treatment on the immune response to SARS-CoV-2. in the lung.
Abstract
Lung transcripts levels of IL-1β, IL-12, IFN-α7, OAS3, Mx2, CCL5 relative to the housekeeping genes RPL18 and RPS6KB1 determined by RT-qPCR. D2: day 2 post infection; D5: day 5 post infection; D15: day 15 post infection. Results are expressed as means ± SEM. Statistical analysis: one-way ANOVA with Tukey’s multiple comparisons test. (TIF)</p- Image
- Figure
- Medicine
- Microbiology
- Molecular Biology
- Biotechnology
- Immunology
- Cancer
- Mental Health
- Infectious Diseases
- Virology
- signs onset
- weight loss
- IFN treatment
- administration
- days post-infection
- lung titers
- day post-infection
- COVID
- interferon treatment
- Syrian hamster model
- SARS-CoV -2 hamster model Impaired type
- day pre-infection
- SARS-CoV -2 infection
- Intranasal type