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Systemic IgA response to TMV-DOST intranasal vaccination.
Abstract
<p>Systemic serum IgA titers against each specific antigen in the pooled sera of mice immunized twice intranasally with the TMV-conjugated tetravalent vaccine as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0194614#pone.0194614.g005" target="_blank">Fig 5</a>.</p- Image
- Figure
- Medicine
- Microbiology
- Biotechnology
- Immunology
- Cancer
- Infectious Diseases
- Biological Sciences not elsewhere classified
- Chemical Sciences not elsewhere classified
- TMV-DOST mixture
- isotype profile
- vaccine potency
- two-dose survival
- multi-antigen subunit vaccine
- tetravalent vaccine
- IgG 2 response
- Tobacco Mosaic virus
- subunit vaccines
- tularensis LVS challenge model
- Tul 4
- protection
- vaccine strain
- tularensis SchuS 4 proteins DnaK
- pathogen challenge
- mucosal immunity
- biothreat agent
- Francisella tularensis
- TMV-DOT
- antigen combination
- Gram-negative encapsulated coccobacillus bacterium
- Francisella tularensis LVS challenge Tularemia
- CDC lists F
- Previous vaccine studies
- two-dose adjuvanted multi-antigen TMV-subunit conjugate vaccine
- Intranasal administration
- antigen carrier
- Immune responses