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Detection of MSI and distribution of number of MSIs in 138 EC patients.
Abstract
<p>(A) Example of MSI and non-MSI cases analyzed by four mononucleotide repeat markers (BAT26, NR21, NR27, and CAT25). (B) Association between MSI, <i>POLE</i> mutation, <i>MLH-1</i> promoter methylation and MMR protein expression. The number of mononucleotide repeat markers showing MSI are shown by color.</p- Image
- Figure
- Biophysics
- Biochemistry
- Cell Biology
- Genetics
- Molecular Biology
- Biotechnology
- Cancer
- bisulfite polymerase chain reaction
- MSI status
- EC patients
- KRAS
- endometrial cancer-specific survival
- IHC
- PCR
- POLE mutations
- endometrial cancer
- MLH 1 deficiency
- MMR proficiency
- 138 EC patients
- microsatellite instability Background
- MSI analysis
- MLH 1 promoter