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Pre-plaque PW-Doppler parameters correlate with plaque length at 9 weeks.
Abstract
<p>(a) Representative PW-Doppler tracing of a proximal RCCA before and after surgery. Note the dramatic decrease in velocity. Measurements of v<sub>max</sub>, time in systole (t<sub>s</sub>) and t<sub>T</sub> (total time) are indicated. (b) v<sub>max</sub> and t<sub>s</sub>/t<sub>T</sub> were calculated from pre-surgery tracings and 2 and 9 weeks after device placement. Data (mean±SEM, n = 7 cuffs, 10 casts), were analyzed by 2 way ANOVA. There was a highly significant effect of device on v<sub>max</sub> and t<sub>s</sub>/t<sub>T</sub> ratio (p<0.005), but no significant difference between cast and cuffs on either parameter. “*” p<0.05 compared to pre-surgery. (c) Using 39 animals fitted with casts, 2 week t<sub>s</sub>/t<sub>T</sub> and v<sub>max</sub> values were calculated and plotted against plaque length at 9 weeks and the correlation determined by linear regression. t<sub>s</sub>/t<sub>T</sub> positively correlated with plaque length (p<0.0005, r = 0.66) between, v<sub>max</sub> and plaque length were negatively correlated (p<0.0005, r = 0.59). Dotted lines indicate 95% confidence interval.</pSimilar works
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Last time updated on 16/03/2018
This paper was published in The Francis Crick Institute.
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