¹H NMR spectra of plasma and urine from control and <i>K. pneumoniae</i> infected rats for 8 hours.

Abstract

<p>Typical 500 MHz ¹H (CPMG) NMR spectra of plasma obtained from a non-infected SD rat (P_A) and a rat infected with <i>K. pneumoniae</i> for 8 hours (P_B). The region of δ 5.0–9.0 in the blood plasma spectra was vertically expanded 16 times compared with the region of δ 0.5–4.5; Representative 600 MHZ ¹H NMR spectra of urine samples obtained from a non-infected SD rat (U_A) and a rat infected with <i>K. pneumoniae</i> for 8 hours (U_B). The spectral region, δ 6.2–9.5, was vertically expanded 4 times compared with the region of δ 0.5–4.4. Key: 1,lipoprotein; 2,valine; 3,leucine; 4,isoleucine; 5,creatine; 6,<i>N</i>-acetyl glycoprotein; 7,<i>O</i>-acetyl glycoprotein; 8,alanine; 9,lactate; 10,acetoacetate; 11,α-glucose; 12,acetate; 13,pyruvate; 14,dihydrothymine; 15,threonine; 16,unsaturated fatty acid; 17,choline; 18,phosphorylcholine; 19,glycerophosphocholine; 20,lysine; 21,citrate; 22,_D-3-hydroxybutyrate; 23,glutamine; 24,glutamate; 25,histidine; 26,phenylalanine; 27,tyrosine; 28,formate; 29,trimethylamine; 30,urea; 31,triglyceride; 32,arginine; 33,ω-3 fatty acid; 34,poly unsaturated fatty acid; 35,glucose and amino acids α-CH resonances; 36,2-oxoglutarate; 37,creatinine; 38,hippurate; 39,1-methylnicotimamide; 40,acetamide; 41,fumarate; 42,phenylacetylglycine; 43,cis-aconitate; 44,pantothenic acid; 45,succinate; 46,<i>N</i>-methylnicotinate; 47,malate; 48,indoxyl sulfate; 49,dimethylamine; 50,glycine; 51,isovalerate; 52,2-(4-hydroxyphenyl)propanoic acid; 53,2,3-dihydroxybutyrate; 54,4-cresol glucuronide; 55,dimethylglycine; 56,taurine; 57,hypotaurine; 58,4-deoxyerythronate; 59,trimethylamine <i>N</i>-oxide.</p