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oaioai:figshare.com:article/217884

The schematic diagram of crosstalk between RhoC and IQGAP1 in gastric cancer.

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Publication date
2013
Publisher
Doi

    Abstract

    <p>When RhoC is stimulated by extracelluar or intracelluar signals, it binds with the scaffold protein IQGAP1, influences the expression of cell cycle-related proteins such as cyclin D1 and cyclin B, affects G1-S transitions in the cell cycle, and then causes the change in cell proliferation. The signal transduction event through which IQGAP1 affects the expression of cyclin still needs to be elucidated.</p

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    The Francis Crick Institute

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    Last time updated on 16/03/2018

    This paper was published in The Francis Crick Institute.

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